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Structure

ZLN-024 Biochemical

ZLN-024

Purity
>98% (HPLC)
Synonyms
ZLN-024; ZLN024; ZLN-024 biochemical
Ordering
Purity/Purification
>98% (HPLC)
Suitability
10mM in DMSO
Target
AMPK
Receptor
AMPK
Chemical Name
Pyrimidine, 2-[[2-(2-bromo-4-methylphenoxy)ethyl]thio]
SMILES
CC1=CC(=C(C=C1)OCCSC2=NC=CC=N2)Br
Molecular Formula
C13H13BrN2OS
CAS Number
723249-01-2
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Structure

Related Product Information for ZLN-024 biochemical
A novel AMPK allosteric activator that has no effect on mitochondrial function or the ADP/ATP ratio; directly activate recombinant AMPK alpha1beta1gamma1 and its homologue alpha2beta1gamma1 with EC50 of 0.42uM and 0.95uM, respectively; also directly activate recombinant AMPK alpha1beta2gamma1 (EC50=1.1 uuM) and AMPK alpha2beta2gamma1 (EC50=0.13uM); activates AMPK in L6 myotubes and stimulates glucose uptake and fatty acid oxidation; improves glucose tolerance, liver tissue weight, triacylglycerol and decreases the total cholesterol content in db/db mice (15mg/kg/day). Diabetes Preclinical
Product Categories/Family for ZLN-024 biochemical
References
1. Zhang LN, et al. PLoS One. 2013 Aug 20; 8 (8):e72092.

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Product Notes

The ZLN-024 (Catalog #AAA3605766) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ZLN-024, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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