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Immunofluorescence (IF) (Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using NOD1 antibody at 1:200 dilution.)

Rabbit NOD1 Polyclonal Antibody | anti-NOD1 antibody

NOD1 Antibody

Gene Names
NOD1; CARD4; NLRC1; CLR7.1
Applications
Immunofluorescence, Immunocytochemistry, Western Blot
Purity
Antigen-Affinity Chromatography
Synonyms
NOD1; Polyclonal Antibody; NOD1 Antibody; Affinity Purified Rabbit Polyclonal NOD1 Antibody; Polyclonal NOD1 antibody; Anti-NOD1 antibody; CARD4 antibody; NOD-1; CLR7.1 antibody; NLRC1 antibody; caspase recruitment domain family member 4 antibody; NOD1 antibody; NOD-1 antibody; NOD 1; NOD 1 antibody; caspase recruitment domain-containing protein 4 antibody; NLR family CARD domain containing 1 antibody; nucleotide-binding oligomerization domain-containing protein 1 antibody; anti-NOD1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen-Affinity Chromatography
Form/Format
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration
1 mg/ml (varies by lot)
Sequence Length
953
Applicable Applications for anti-NOD1 antibody
Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB)
Application Notes
IF: 1:100-1:200
WB: 1:500-1:3000
Cross-Reactivity
Human
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Immunofluorescence (IF)

(Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using NOD1 antibody at 1:200 dilution.)

Immunofluorescence (IF) (Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using NOD1 antibody at 1:200 dilution.)

Western Blot (WB)

(Western blot analysis of 30 ug of whole cell lysate (A: H1299) using a 7.5% SDS PAGE gel and NOD1 antibody at a dilution of 1:1000)

Western Blot (WB) (Western blot analysis of 30 ug of whole cell lysate (A: H1299) using a 7.5% SDS PAGE gel and NOD1 antibody at a dilution of 1:1000)
Related Product Information for anti-NOD1 antibody
This gene encodes a member of the NOD family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain, a centrally located nucleotide-binding domain, and 10 tandem leucine-rich repeats in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.
Product Categories/Family for anti-NOD1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
108 kDa
NCBI Official Full Name
nucleotide-binding oligomerization domain-containing protein 1 isoform 1
NCBI Official Synonym Full Names
nucleotide binding oligomerization domain containing 1
NCBI Official Symbol
NOD1
NCBI Official Synonym Symbols
CARD4; NLRC1; CLR7.1
NCBI Protein Information
nucleotide-binding oligomerization domain-containing protein 1
UniProt Protein Name
Nucleotide-binding oligomerization domain-containing protein 1
UniProt Gene Name
NOD1
UniProt Synonym Gene Names
CARD4
UniProt Entry Name
NOD1_HUMAN

NCBI Description

This gene encodes a member of the nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family of proteins. The encoded protein plays a role in innate immunity by acting as a pattern-recognition receptor (PRR) that binds bacterial peptidoglycans and initiates inflammation. This protein has also been implicated in the immune response to viral and parasitic infection. Major structural features of this protein include an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. Mutations in this gene are associated with asthma, inflammatory bowel disease, Behcet disease and sarcoidosis in human patients. [provided by RefSeq, Aug 2017]

Research Articles on NOD1

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Product Notes

The NOD1 nod1 (Catalog #AAA5312227) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's NOD1 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB). IF: 1:100-1:200 WB: 1:500-1:3000. Researchers should empirically determine the suitability of the NOD1 nod1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NOD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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