Structure
AICAR Biochemical
AICAR
Purity
>98% (HPLC)
Synonyms
AICAR; Acadesine; AICA Riboside; AICAR biochemical
Purity/Purification
>98% (HPLC)
Suitability
DMSO: >=30mg/mL
Target
AMPK
Receptor
AMPK
Chemical Name
1H-Imidazole-4-carboxamide, 5-amino-1-beta-D-ribofuranosyl
SMILES
O=C(C1=C(N)N([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C=N1)N
Molecular Formula
C9H14N4O5
CAS Number
2627-69-2
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for AICAR biochemical
AICAR (Acadesine, AICA Riboside, NSC 105823) is a selective AMPK activator in both hepatocytes and adipocytes; inhibits the synthesis of fatty acids and sterols and inactivates HMG-CoA reductase in rat hepatocytes at 0.5 mM, inhibits insulin-stimulated glucose and reduces GLUT4 translocation in 3T3-L1 adipocytes; down-regulates the insulin receptor expression in HepG2 cells.
Product Categories/Family for AICAR biochemical
References
1. Sullivan JE, et al. FEBS Lett. 1994 Oct 10; 353 (1):33-6.
2. Young ME, et al. FEBS Lett. 1996 Mar 11; 382 (1-2):43-7.
3. Samari HR, et al. J Biol Chem. 1998 Sep 11; 273 (37):23758-63.
4. Ayasolla KR, et al. J Neuroinflammation. 2005 Sep 20; 2:21.
2. Young ME, et al. FEBS Lett. 1996 Mar 11; 382 (1-2):43-7.
3. Samari HR, et al. J Biol Chem. 1998 Sep 11; 273 (37):23758-63.
4. Ayasolla KR, et al. J Neuroinflammation. 2005 Sep 20; 2:21.
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Product Notes
The AICAR (Catalog #AAA3603801) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "AICAR, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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