Western Blot (WB)
(Western Blot (WB) analysis of MLKL Rabbit mAb at 1:1000 dilutionLane1:HT29 whole cell lysateLane2:HUVEC whole cell lysateLane3:Hela whole cell lysate)
Rabbit anti-Human MLKL Monoclonal Antibody | anti-MLKL antibody
MLKL Rabbit Monoclonal Antibody
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Protein A affinity purified
Synonyms
MLKL; Monoclonal Antibody; MLKL Rabbit Monoclonal Antibody; Mixed lineage kinase domain-like protein; anti-MLKL antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Specificity
This antibody detects endogenous levels of MLKL and does not cross-react with related proteins.
Purity/Purification
Protein A affinity purified
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Applicable Applications for anti-MLKL antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:1000-1:5000
IHC: 1:50-1:200
IHC: 1:50-1:200
Immunogen
Recombinant antibody.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of MLKL Rabbit mAb at 1:1000 dilutionLane1:HT29 whole cell lysateLane2:HUVEC whole cell lysateLane3:Hela whole cell lysate)
Western Blot (WB)
(Western Blot (WB) analysis of MLKL Rabbit mAb at 1:1000 dilutionLane1:HT29 whole cell lysateLane2:HUVEC whole cell lysateLane3:Hela whole cell lysate)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-MLKL antibody. Counter stained with hematoxylin)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-MLKL antibody. Counter stained with hematoxylin)
Related Product Information for anti-MLKL antibody
MLKL (mixed lineage kinase domain-like) is a 471 amino acid protein that contains one protein kinase domain which is thought to be catalytically inactive. The gene encoding MLKL maps to chromosome 16 and is expressed as two isoforms which are produced by alternative splicing events. Chromosome 16, which is associated with a variety of genetic disorders, encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
NCBI and Uniprot Product Information
UniProt Accession #
Molecular Weight
~ 54kDa
Protein Family
Similar Products
Product Notes
The MLKL (Catalog #AAA3014047) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MLKL Rabbit Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MLKL can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:1000-1:5000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the MLKL for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MLKL, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
