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Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using (KCNA10 Antibody) at dilution 1/40.)

Rabbit anti-Human, Mouse KCNA10 Polyclonal Antibody | anti-KCNA10 antibody

KCNA10 Antibody

Gene Names
KCNA10; Kcn1; Kv1.8
Reactivity
Human, Mouse
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
KCNA10; Polyclonal Antibody; KCNA10 Antibody; Kcn1; Kv1.8; anti-KCNA10 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Antigen affinity purification
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
0.7mg/mL (varies by lot)
Applicable Applications for anti-KCNA10 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:30-1:150
Immunogen
Synthetic peptide of human KCNA10
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C for 1 year.

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using (KCNA10 Antibody) at dilution 1/40.)

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using (KCNA10 Antibody) at dilution 1/40.)
Related Product Information for anti-KCNA10 antibody
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA2 and KCNA3 on chromosome 1.
Product Categories/Family for anti-KCNA10 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
58kDa
NCBI Official Full Name
potassium voltage-gated channel subfamily A member 10
NCBI Official Synonym Full Names
potassium voltage-gated channel subfamily A member 10
NCBI Official Symbol
KCNA10
NCBI Official Synonym Symbols
Kcn1; Kv1.8
NCBI Protein Information
potassium voltage-gated channel subfamily A member 10
UniProt Protein Name
Keratin-associated protein 1-1
UniProt Gene Name
KRTAP1-1
UniProt Synonym Gene Names
B2A; KAP1.1; KAP1.6; KAP1.7; KRTAP1.1
UniProt Entry Name
KRA11_HUMAN

NCBI Description

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA2 and KCNA3 on chromosome 1. [provided by RefSeq, Jul 2008]

Uniprot Description

KRTAP1-1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. Belongs to the KRTAP type 1 family. Interacts with hair keratins

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: keratin filament

Research Articles on KCNA10

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Product Notes

The KCNA10 krtap1-1 (Catalog #AAA9434789) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KCNA10 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's KCNA10 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:30-1:150. Researchers should empirically determine the suitability of the KCNA10 krtap1-1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KCNA10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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