Rabbit RAB39 Polyclonal Antibody | anti-RAB39 antibody

RAB39 Polyclonal Antibody

Cat. Num. AAA3006469

• Gene Names: RAB39A; RAB39
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: RAB39; Polyclonal Antibody; RAB39 Polyclonal Antibody; Ras-related protein Rab-39A; Rab-39; RAB39A; anti-RAB39 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: RAB39 polyclonal antibody detects endogenous levels of RAB39 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 217

• Applicable Applications for anti-RAB39 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: A synthetic peptide corresponding to residues in Human RAB39.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of RAB39 polyclonal antibody at 1:500 dilutionLane1:Hela whole cell lysateLane2:Rat lung tissue lysateLane3:H9C2 whole cell lysate)

Related Product Information for anti-RAB39 antibody

The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies, all of which are thought to play an important role in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum (ER) to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 39, also known as Rab 39A, is a 217 amino acid protein that belongs to the small GTPase superfamily. Rab 39 may be involved in vesicular trafficking.

NCBI and Uniprot Product Information

• NCBI GI #: 39930371
• NCBI GeneID: 54734
• NCBI Accession #: NP_059986.1
• NCBI GenBank Nucleotide #: NP_059986.1
• UniProt Accession #: Q14964
• Molecular Weight: ~ 25kDa
• NCBI Official Full Name: ras-related protein Rab-39A
• NCBI Official Synonym Full Names: RAB39A, member RAS oncogene family
• NCBI Official Symbol: RAB39A
• NCBI Official Synonym Symbols: RAB39
• NCBI Protein Information: ras-related protein Rab-39A
• UniProt Protein Name: Ras-related protein Rab-39A
• UniProt Gene Name: RAB39A
• UniProt Synonym Gene Names: RAB39; Rab-39
• UniProt Entry Name: RB39A_HUMAN

Uniprot Description

Function: Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in vesicular trafficking. Plays a role in the fusion of phagosomes with lysosomes. Ref.5

Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side

Potential. Cytoplasmic vesicle › phagosome. Cytoplasmic vesicle › phagosome membrane; Lipid-anchor; Cytoplasmic side

By similarity. Note: Recruited to phagosomes containing S.aureus or M.tuberculosis. Ref.5

Sequence similarities: Belongs to the small GTPase superfamily. Rab family.