Rabbit RAB7L1 Polyclonal Antibody | anti-RAB7L1 antibody

RAB7L1 Polyclonal Antibody

Cat. Num. AAA3006128

• Gene Names: RAB29; RAB7L; RAB7L1
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: RAB7L1; Polyclonal Antibody; RAB7L1 Polyclonal Antibody; Ras-related protein Rab-7L1; Rab-7-like protein 1; RAB-7L1; anti-RAB7L1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: RAB7L1 polyclonal antibody detects endogenous levels of RAB7L1 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 203

• Applicable Applications for anti-RAB7L1 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: Synthetic peptide, corresponding to amino acids 156-201 of Human RAB7L1.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of RAB7L1 polyclonal antibody at 1:500 dilutionLane1:HEK293T cell lysateLane2:sp2/0 cell lysateLane3:PC12 cell lysate)

Related Product Information for anti-RAB7L1 antibody

The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies. Increasing data suggests an important role for Rab proteins in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum (ER) to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 7L1, also known as RAB7L, is a 203 amino acid, ubiquitously expressed member of the Rab family of proteins that localizes to the cell membrane. Rab 7L1 contains four GTP-binding domains and shares 35% identity with Rab 7 and 94% identity with the rat protein Rab 29. In addition, Rab 7L1 is often used as a marker of T cells.

NCBI and Uniprot Product Information

• NCBI GI #: 208609962
• NCBI GeneID: 8934
• NCBI Accession #: NP_001129134.1
• NCBI GenBank Nucleotide #: NP_001129134.1
• UniProt Accession #: O14966
• Molecular Weight: ~ 23kDa
• NCBI Official Full Name: ras-related protein Rab-7L1 isoform 1
• NCBI Official Synonym Full Names: RAB29, member RAS oncogene family
• NCBI Official Symbol: RAB29
• NCBI Official Synonym Symbols: RAB7L; RAB7L1
• NCBI Protein Information: ras-related protein Rab-7L1
• UniProt Protein Name: Ras-related protein Rab-7L1
• UniProt Gene Name: RAB7L1
• UniProt Entry Name: RAB7L_HUMAN

Uniprot Description

RAB7L1: Belongs to the small GTPase superfamily. Rab family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein, monomeric; G protein, monomeric, Rab; G protein

Chromosomal Location of Human Ortholog: 1q32

Cellular Component: cytoskeleton; mitochondrion; perinuclear region of cytoplasm; cytoplasm; melanosome; plasma membrane; vacuole; trans-Golgi network

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding

Biological Process: protein transport; ER to Golgi vesicle-mediated transport; melanosome organization and biogenesis; metabolic process; cell differentiation; Rab protein signal transduction; Golgi organization and biogenesis