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Immunohistochemistry (IHC) (Anti-LAMP1 / CD107a antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit anti-Human, Mouse LAMP1 / CD107a Polyclonal Antibody | anti-LAMP1 antibody

Rabbit Polyclonal to Human LAMP1 / CD107a

Gene Names
LAMP1; LAMPA; CD107a; LGP120
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Immunofluorescence, Western Blot
Purity
Immunoaffinity Purified
Synonyms
LAMP1 / CD107a; Polyclonal Antibody; Rabbit Polyclonal to Human LAMP1 / CD107a; Anti-LAMP1 / CD107a Antibody (aa131-161) IHC-plus; LAMP1; CD107a; CD107a antigen; LAMP-1; LGP120; LAMPA; Human LAMP1; anti-LAMP1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
Human CD107a / LAMP1
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.09% sodium azide
Sequence Length
417
Applicable Applications for anti-LAMP1 antibody
Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB)
Application Notes
IF (1:200), IHC-P (1:10 - 1:100), WB (1:1000)
Target Species
Human
Immunogen Description
KLH-conjugated synthetic peptide from N-terminal region of human LAMP1.
Immunogen Type
Synthetic peptide
Immunogen
LAMP1 / CD107a antibody was raised against kLH-conjugated synthetic peptide from N-terminal region of human LAMP1.
Antigen Modification
aa131-161
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Immunohistochemistry (IHC)

(Anti-LAMP1 / CD107a antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-LAMP1 / CD107a antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with *LAMP1 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.)

Immunohistochemistry (IHC) (Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with *LAMP1 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.)

Western Blot (WB)

(Western blot of LAMP1 Antibody (N-term) in mouse lung tissue lysates (35 ug/lane).LAMP1 (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot of LAMP1 Antibody (N-term) in mouse lung tissue lysates (35 ug/lane).LAMP1 (arrow) was detected using the purified Pab.)

Western Blot (WB)

(Western blot of LAMP1 Antibody (N-term) in Y79 cell line lysates (35 ug/lane). LAMP1 (arrow) was detected using the purified Pab (1:60 dilution).)

Western Blot (WB) (Western blot of LAMP1 Antibody (N-term) in Y79 cell line lysates (35 ug/lane). LAMP1 (arrow) was detected using the purified Pab (1:60 dilution).)
Related Product Information for anti-LAMP1 antibody
LAMP1, also known as CD107a, is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. LAMP1 may also play a role in tumor cell metastasis. It has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,986 Da
NCBI Official Full Name
lysosome-associated membrane glycoprotein 1
NCBI Official Synonym Full Names
lysosomal-associated membrane protein 1
NCBI Official Symbol
LAMP1
NCBI Official Synonym Symbols
LAMPA; CD107a; LGP120
NCBI Protein Information
lysosome-associated membrane glycoprotein 1; LAMP-1; CD107 antigen-like family member A; lysosome-associated membrane protein 1
UniProt Protein Name
Lysosome-associated membrane glycoprotein 1
UniProt Gene Name
LAMP1
UniProt Synonym Gene Names
LAMP-1; Lysosome-associated membrane protein 1
UniProt Entry Name
LAMP1_HUMAN

NCBI Description

The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008]

Uniprot Description

LAMP1: Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. Belongs to the LAMP family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 13q34

Cellular Component: multivesicular body; cell soma; membrane; lysosome; integral to plasma membrane; cytoplasm; dendrite; late endosome; plasma membrane; melanosome; endosome membrane; sarcolemma; external side of plasma membrane

Molecular Function: protein domain specific binding; protein binding; enzyme binding

Biological Process: positive regulation of natural killer cell degranulation; induction of apoptosis by granzyme; protein stabilization; viral reproduction; autophagic cell death; autophagy; positive regulation of natural killer cell mediated cytotoxicity

Research Articles on LAMP1

Similar Products

Product Notes

The LAMP1 lamp1 (Catalog #AAA248512) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human LAMP1 / CD107a reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's LAMP1 / CD107a can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB). IF (1:200), IHC-P (1:10 - 1:100), WB (1:1000). Researchers should empirically determine the suitability of the LAMP1 lamp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LAMP1 / CD107a, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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