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Immunohistochemistry (IHC) (Anti-LAMP1 / CD107a antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Mouse LAMP1 / CD107a Monoclonal Antibody | anti-LAMP1 / CD107a antibody

Anti-LAMP1 / CD107a Antibody (clone H4A3) IHC-plus

Gene Names
LAMP1; LAMPA; CD107a; LGP120
Reactivity
Mouse, Human, Primate
Applications
Immunohistochemistry, Immunocytochemistry, Western Blot, Flow Cytometry, Functional Assay
Purity
Protein A purified
Synonyms
LAMP1 / CD107a; Monoclonal Antibody; Anti-LAMP1 / CD107a Antibody (clone H4A3) IHC-plus; Mouse Monoclonal [clone H4A3] (IgG1) to Human LAMP1 / CD107a; Human LAMP1 / CD107a; CD107a antigen; LAMP-1; LGP120; LAMPA; anti-LAMP1 / CD107a antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Mouse, Human, Primate
Clonality
Monoclonal
Isotype
IgG1
Clone Number
H4A3
Specificity
Monoclonal antibody H4A3 recognizes CD107a, an approximately 100-120 kD glycoprotein expressed mainly on lysosomal, but also on the plasma membrane.
Purity/Purification
Protein A purified
Form/Format
PBS, pH 7.4, sterile filtered.
Concentration
1 mg/ml (varies by lot)
Sequence Length
417
Applicable Applications for anti-LAMP1 / CD107a antibody
Immunohistochemistry (IHC) Formalin/Paraffin, Immunocytochemistry (ICC), Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes
ICC (2 - 10 ug/ml)
IHC-P (10 ug/ml)
Immunogen
LAMP1 / CD107a antibody was raised against human PBMC.
Immunogen Description
Human PBMC.
Immunogen Type
Cells
Target Species
Human
Preparation and Storage
Store at 2-8 degree C. Do not freeze.

Immunohistochemistry (IHC)

(Anti-LAMP1 / CD107a antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-LAMP1 / CD107a antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-LAMP1 / CD107a antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-LAMP1 / CD107a antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-LAMP1 / CD107a antibody
LAMP1 Antibody, CD107a Antibody, CD107a antigen Antibody, LAMP-1 Antibody, LGP120 Antibody, LAMPA Antibody Description: LAMP1, also known as CD107a, is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. LAMP1 may also play a role in tumor cell metastasis. It has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,986 Da
NCBI Official Full Name
lysosome-associated membrane glycoprotein 1
NCBI Official Synonym Full Names
lysosomal associated membrane protein 1
NCBI Official Symbol
LAMP1
NCBI Official Synonym Symbols
LAMPA; CD107a; LGP120
NCBI Protein Information
lysosome-associated membrane glycoprotein 1
UniProt Protein Name
Lysosome-associated membrane glycoprotein 1
UniProt Gene Name
LAMP1
UniProt Synonym Gene Names
LAMP-1; Lysosome-associated membrane protein 1
UniProt Entry Name
LAMP1_HUMAN

NCBI Description

The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008]

Uniprot Description

LAMP1: Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. Belongs to the LAMP family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 13q34

Cellular Component: cell soma; cytoplasm; dendrite; endosome membrane; external side of plasma membrane; integral to plasma membrane; late endosome; lysosomal membrane; lysosome; melanosome; membrane; multivesicular body; perinuclear region of cytoplasm; plasma membrane; sarcolemma; synaptic vesicle

Molecular Function: enzyme binding; protein binding; protein domain specific binding; viral receptor activity

Biological Process: autophagic cell death; autophagy; entry of virus into host cell; induction of apoptosis by granzyme; positive regulation of natural killer cell degranulation; positive regulation of natural killer cell mediated cytotoxicity; protein stabilization

Research Articles on LAMP1 / CD107a

Similar Products

Product Notes

The LAMP1 / CD107a lamp1 (Catalog #AAA249345) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-LAMP1 / CD107a Antibody (clone H4A3) IHC-plus reacts with Mouse, Human, Primate and may cross-react with other species as described in the data sheet. AAA Biotech's LAMP1 / CD107a can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Formalin/Paraffin, Immunocytochemistry (ICC), Western Blot (WB), Flow Cytometry (FC/FACS). ICC (2 - 10 ug/ml) IHC-P (10 ug/ml). Researchers should empirically determine the suitability of the LAMP1 / CD107a lamp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LAMP1 / CD107a, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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