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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human testis using MBS7604457 (SRGAP1 antibody) at dilution of 1:50)

Rabbit SRGAP1 Polyclonal Antibody | anti-SRGAP1 antibody

SRGAP1 Rabbit Polyclonal

Gene Names
SRGAP1; NMTC2; ARHGAP13
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry, Immunoprecipitation
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
SRGAP1; Polyclonal Antibody; SRGAP1 Rabbit Polyclonal; anti-SRGAP1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
1085
Applicable Applications for anti-SRGAP1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Immunogen
SLIT-ROBO Rho GTPase activating protein 1
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis using MBS7604457 (SRGAP1 antibody) at dilution of 1:50)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human testis using MBS7604457 (SRGAP1 antibody) at dilution of 1:50)

Western Blot (WB)

(mouse brain tissue were subjected to SDS PAGE followed by western blot with MBS7604457 (SRGAP1 antibody) at dilution of 1:800)

Western Blot (WB) (mouse brain tissue were subjected to SDS PAGE followed by western blot with MBS7604457 (SRGAP1 antibody) at dilution of 1:800)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
121,594 Da
NCBI Official Full Name
SLIT-ROBO Rho GTPase-activating protein 1
NCBI Official Synonym Full Names
SLIT-ROBO Rho GTPase activating protein 1
NCBI Official Symbol
SRGAP1
NCBI Official Synonym Symbols
NMTC2; ARHGAP13
NCBI Protein Information
SLIT-ROBO Rho GTPase-activating protein 1
UniProt Protein Name
SLIT-ROBO Rho GTPase-activating protein 1
UniProt Gene Name
SRGAP1
UniProt Synonym Gene Names
ARHGAP13; KIAA1304; srGAP1
UniProt Entry Name
SRGP1_HUMAN

Uniprot Description

ARHGAP13: GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs, Rac/Rho; GAPs

Chromosomal Location of Human Ortholog: 12q14.2

Cellular Component: cytoplasm; cytosol

Molecular Function: GTPase activator activity; protein binding; Rac GTPase binding

Biological Process: negative regulation of cell migration; positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction; signal transduction

Disease: Thyroid Carcinoma, Follicular

Research Articles on SRGAP1

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Product Notes

The SRGAP1 srgap1 (Catalog #AAA7604457) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SRGAP1 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SRGAP1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the SRGAP1 srgap1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SRGAP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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