Goat CCR10 Polyclonal Antibody | anti-CCR10 antibody

GOAT ANTI MOUSE CCR10

Cat. Num. AAA223513

• Gene Names: Ccr10; Gpr2; Cmkbr9
• Applications: ELISA, Flow Cytometry, Functional Assay, Immunohistochemistry, Western Blot
• Synonyms: CCR10; Polyclonal Antibody; GOAT ANTI MOUSE CCR10; anti-CCR10 antibody

• Host: Goat
• Clonality: Polyclonal
• Isotype: IgG
• Form/Format: Purified; Purified IgG - liquid
• Concentration: IgG concentration 1.0 mg/ml (varies by lot)
• Sequence Length: 362

• Applicable Applications for anti-CCR10 antibody: ELISA (EIA), Flow cytometry (FC/FACS), Immunohistology Paraffin, Western Blot (WB)
• Application Notes: ELISA: This product is suitable for use in indirect ELISA applications.; Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. ; ELISA: Minimum Dilution: 1/100000; Immunohistology - Paraffin: Minimum Dilution: 1/250; Western Blotting: Minimum Dilution: 1/1000
• Perservative Stabilisers: 0.1% Sodium Azide (NaN3); 0.1% Bovine Serum Albumin
• Histology Positive Control Tissue: Mouse small intestine; Buffer Solution
• Antiserum Preparation: Antiserum to mouse CCR10 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
• Target Species: Mouse
• Preparation and Storage: Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.; Shelf Life: 18 months from date of despatch.

Testing Data #1

(Staining of paraffin embedded mouse small intestine with Goat anti mouse CCR10 (MBS223513))

Related Product Information for anti-CCR10 antibody

Goat anti Mouse CCR10 recognizes mouse CCR10 (C-C chemokine receptor type 10), otherwise known as GPR2, (G-protein coupled receptor 2), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, highly expressed in the small intestine, colon, lymph nodes and Peyer patches, which acts as a receptor for the chemokines CCL27 (SCYA27/CTACK) and CCL28 (SCYA28). This product is reported as suitable for use in immunocytochemistry and shows minimal cross-reactivity with human CCR10.

NCBI and Uniprot Product Information

• NCBI GI #: 11024708
• NCBI GeneID: 12777
• NCBI Accession #: NP_031747.2
• NCBI GenBank Nucleotide #: NM_007721.4
• UniProt Accession #: Q9JL21; Q542A4; Q9JIP1; Q9JL20
• Molecular Weight: 38,900 Da
• NCBI Official Full Name: C-C chemokine receptor type 10
• NCBI Official Synonym Full Names: chemokine (C-C motif) receptor 10
• NCBI Official Symbol: Ccr10
• NCBI Official Synonym Symbols: Gpr2; Cmkbr9
• NCBI Protein Information: C-C chemokine receptor type 10; C-C CKR-10; CC-CKR-10; CCR-10; G protein-coupled receptor 2; G-protein coupled receptor 2; chemokine C-C receptor 9
• UniProt Protein Name: C-C chemokine receptor type 10
• Protein Family: C-C chemokine receptor
• UniProt Gene Name: Ccr10
• UniProt Synonym Gene Names: Cmkbr9; Gpr2; C-C CKR-10; CC-CKR-10; CCR-10
• UniProt Entry Name: CCR10_MOUSE

Uniprot Description

CCR10: Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1

Cellular Component: cell surface; membrane; integral to plasma membrane; cell; plasma membrane; integral to membrane; cytosol

Molecular Function: G-protein coupled receptor activity; signal transducer activity; protein binding; C-C chemokine receptor activity; chemokine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; immune response; chemotaxis; signal transduction