SDS-Page
Serpine2 recombinant protein
Serpine2, 20-397aa, Mouse, His-tag, Baculovirus
Gene Names
Serpine2; PI7; PI-7; PN-1; Spi4; PAI-1; B230326M24Rik
Applications
SDS-Page
Purity
> 95% by SDS-PAGE
Synonyms
Serpine2; 20-397aa; Mouse; His-tag; Baculovirus; Glia-derived nexin; Serpnie2; B230326M24Rik; PAI-1; PI-7; PI7; PN-1; Spi4; GDN; GDN_HUMAN; GDNPF; Glia derived nexin; Glial derived neurite promoting factor; P17; Peptidase inhibitor 7 Pi-7; Plasminogen activator inhibitor type 1; member 2 PN-1; PN1; PNI; Protease inhibitor 7; Protease nexin 1; Protease nexin I; Serpin E2; Serpin peptidase inhibitor; clade E (nexin; plasminogen activator inhibitor type 1); member 2; SERPINE 2; Serpine2 recombinant protein
Host
Baculovirus
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol
Concentration
0.5 mg/ml (determined by Absorbance at 280nm) (varies by lot)
Sequence
SQFNSLSLEE LGSNTGIQVF NQIIKSRPHE NVVVSPHGIA SILGMLQLGA DGKTKKQLST VMRYNVNGVG KVLKKINKAI VSKKNKDIVT VANAVFLRNG FKMEVPFAVR NKDVFQCEVQ NVNFQDPASA SESINFWVKN ETRGMIDNLL SPNLIDGALT RLVLVNAVYF KGLWKSRFQP ESTKKRTFVA GDGKSYQVPM LAQLSVFRSG STRTPNGLWY NFIELPYHGE SISMLIALPT ESSTPLSAII PHITTKTIDS WMNTMVPKRM QLVLPKFTAV AQTDLKEPLK ALGITEMFEP SKANFTKITR SESLHVSHIL QKAKIEVSED GTKASAATTA ILIARSSPPW FIVDRPFLFS IRHNPTGAIL FLGQVNKPLE HHHHHH
Sequence Length
397
Applicable Applications for Serpine2 recombinant protein
SDS-PAGE
Antigen Species
Mouse
Tag Information
His-tag
Endotoxin Level
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
SDS-Page
SDS-Page
Related Product Information for Serpine2 recombinant protein
Serpine2, as known as glia-derived nexin, is a member of the Serpin superfamily of the serine protease inhibitors. This protein is a potent inhibitor of thrombin, plasmin and plasminogen activators. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuron-like cells. Also, it is over expression in mice leads to progressive neuronal and motor dysfunction in these animals. Recombinant mouse Serpine2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques
Product Categories/Family for Serpine2 recombinant protein
References
Lu CH., et al. (2013) PLoS ONE 8:E74602.; McKee CM., et al. (2012) J. Clin. Invest. 122:4025-4036.;
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42.9kDa (386aa) 40-57kDa (SDS-PAGE under reducing conditions.)
NCBI Official Full Name
glia-derived nexin
NCBI Official Synonym Full Names
serine (or cysteine) peptidase inhibitor, clade E, member 2
NCBI Official Symbol
Serpine2
NCBI Official Synonym Symbols
PI7; PI-7; PN-1; Spi4; PAI-1; B230326M24Rik
NCBI Protein Information
glia-derived nexin
UniProt Protein Name
Glia-derived nexin
Protein Family
UniProt Gene Name
Serpine2
UniProt Synonym Gene Names
Pi7; Pn1; Spi4; GDN; PI-7; PN-1
Uniprot Description
Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin.
Research Articles on Serpine2
Similar Products
Product Notes
The Serpine2 serpine2 (Catalog #AAA206407) is a Recombinant Protein produced from Baculovirus and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's Serpine2 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the Serpine2 serpine2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: SQFNSLSLEE LGSNTGIQVF NQIIKSRPHE NVVVSPHGIA SILGMLQLGA DGKTKKQLST VMRYNVNGVG KVLKKINKAI VSKKNKDIVT VANAVFLRNG FKMEVPFAVR NKDVFQCEVQ NVNFQDPASA SESINFWVKN ETRGMIDNLL SPNLIDGALT RLVLVNAVYF KGLWKSRFQP ESTKKRTFVA GDGKSYQVPM LAQLSVFRSG STRTPNGLWY NFIELPYHGE SISMLIALPT ESSTPLSAII PHITTKTIDS WMNTMVPKRM QLVLPKFTAV AQTDLKEPLK ALGITEMFEP SKANFTKITR SESLHVSHIL QKAKIEVSED GTKASAATTA ILIARSSPPW FIVDRPFLFS IRHNPTGAIL FLGQVNKPLE HHHHHH. It is sometimes possible for the material contained within the vial of "Serpine2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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