Macrophage Inflammatory Protein 1 beta Active Protein | CCL4L1 active protein
Macrophage Inflammatory Protein 1 beta, Recombinant, Human (CCL4, Chemokine (C-C Motif) Ligand 4, ACT2, Act-2, ACT-2, AT744.1, G-26, G-26 T-lymphocyte-secreted Protein, H400, HC21, LAG1, LAG-1, Lymphocyte Activation Gene 1 Protein, MGC104418, MGC126025, M
Gene Names
CCL4L1; CCL4; MIP1B; SCYA4
Purity
Highly PurifiedPurified. 95% pure by SDS gel electrophoresis.
Synonyms
Macrophage Inflammatory Protein 1 beta; Recombinant; Human (CCL4; Chemokine (C-C Motif) Ligand 4; ACT2; Act-2; ACT-2; AT744.1; G-26; G-26 T-lymphocyte-secreted Protein; H400; HC21; LAG1; LAG-1; Lymphocyte Activation Gene 1 Protein; MGC104418; MGC126025; M; CCL4L1 active protein
Host
Yeast
Purity/Purification
Highly Purified
Purified. 95% pure by SDS gel electrophoresis.
Purified. 95% pure by SDS gel electrophoresis.
Form/Format
Supplied as a lyophilized powder in PBS
Biological Activity
The biological activity of recombinant human MIP-1&# alpha is determined by its use as a cofactor for CSF-dependent myelopoiesis.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Reconstitute to with sterile dH2O or buffer, aliquot and store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for CCL4L1 active protein
Macrophage Inflammatory Protein-1((MIP-1& alpha) is part of the CC subfamily of the chemokine superfamily of chemoattractant cytokines. MIP-1& alpha affects the inflammatory response of blood monocytes, tissue macrophages, and T cells. MIP-1& alpha also enhances the formation of granulocyte-macrophage colonies stimulated by GM-CSF or M-CSF. Human MIP-1& alpha is composed of 69 aa residues with one possible N-linked glycosylation sites, and several possible O-linked sites. Human MIP-1& alpha is 60% homologous with human MIP-1& alpha.
Product Categories/Family for CCL4L1 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
8kD
NCBI Official Full Name
macrophage inflammatory protein 1 beta
NCBI Official Symbol
CCL4L1
NCBI Official Synonym Symbols
CCL4; MIP1B; SCYA4
NCBI Protein Information
C-C motif chemokine 4; MIP-1-beta; chemokine CCL4/MIP-1BETA; small-inducible cytokine A4; macrophage inflammatory protein 1 beta; macrophage inflammatory protein 1-beta
UniProt Protein Name
C-C motif chemokine 4
Protein Family
UniProt Gene Name
CCL4
UniProt Synonym Gene Names
MIP1B; SCYA4
UniProt Entry Name
CCL4_MACMU
Uniprot Description
Function: Monokine with inflammatory and chemokinetic properties
Subunit structure: Homodimer. Interacts with CCR5
Subcellular location: Secreted
Tissue specificity: Detected in peripheral blood mononuclear cells and lymph nodes. Ref.2
Induction: Up-regulated in SIV or SHIV infected monkeys with decreased CD4+ T-cell count. Ref.2
Sequence similarities: Belongs to the intercrine beta (chemokine CC) family.
Research Articles on CCL4L1
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Product Notes
The CCL4L1 ccl4 (Catalog #AAA650337) is an Active Protein produced from Yeast and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Macrophage Inflammatory Protein 1 beta, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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