Typical Testing Data/Standard Curve (for reference only)
Mouse Protein Wnt-7a ELISA Kit | Wnt7a elisa kit
Mouse Protein Wnt-7a ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.
NCBI and Uniprot Product Information
Uniprot Description
WNT7A: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts. Defects in WNT7A are the cause of limb pelvis hypoplasia aplasia syndrome (LPHAS). A syndrome of severe deficiency of the extremities due to hypo- or aplasia of one or more long bones of one or more limbs. Pelvic manifestations include hip dislocation, hypoplastic iliac bone and aplastic pubic bones. Thoracic deformity, unusual facies and genitourinary anomalies can be present. Defects in WNT7A are a cause of Fuhrmann syndrome (FUHRS); also known as fibular aplasia or hypoplasia femoral bowing and poly- syn- and oligodactyly. Fuhrmann syndrome is a distinct limb-malformation disorder characterized also by various degrees of limb aplasia/hypoplasia and joint dysplasia. Belongs to the Wnt family.
Protein type: Secreted, signal peptide; Secreted
Cellular Component: cell surface; extracellular region; extracellular space; proteinaceous extracellular matrix
Molecular Function: cytokine activity; frizzled binding; protein binding; receptor agonist activity; receptor binding
Biological Process: angiogenesis; asymmetric protein localization; cartilage condensation; cartilage development; cell fate commitment; cell proliferation in forebrain; cell-cell signaling; central nervous system vasculogenesis; cerebellar granule cell differentiation; chondrocyte differentiation; dorsal/ventral pattern formation; embryonic axis specification; embryonic digit morphogenesis; embryonic forelimb morphogenesis; embryonic hindlimb morphogenesis; embryonic limb morphogenesis; establishment of cell polarity; fallopian tube development; forelimb morphogenesis; hindlimb morphogenesis; limb development; multicellular organismal development; negative regulation of apoptosis; negative regulation of neurogenesis; neurotransmitter secretion; organ morphogenesis; palate development; positive regulation of cell proliferation; positive regulation of epithelial cell proliferation involved in wound healing; positive regulation of JNK cascade; positive regulation of synaptogenesis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of axon diameter; regulation of axonogenesis; regulation of cell proliferation; reproductive structure development; response to estrogen stimulus; satellite cell activation; satellite cell compartment self-renewal involved in skeletal muscle regeneration; signal transduction; skeletal morphogenesis; skin morphogenesis; somatic stem cell division; somatic stem cell maintenance; stem cell development; synapse organization and biogenesis; uterus development; Wnt receptor signaling pathway; Wnt receptor signaling pathway through beta-catenin
Research Articles on Wnt7a
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Product Notes
The Mouse Wnt7a wnt7a (Catalog #AAA2884712) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2884712 ELISA Kit recognizes Mouse Wnt7a. It is sometimes possible for the material contained within the vial of "Protein Wnt-7a, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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