Vitronectin, Native Protein | VTN protein
Vitronectin, Human, Native
98% pure (SDS-PAGE).
98% pure (SDS-PAGE).
NCBI and Uniprot Product Information
Uniprot Description
Function: Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway
By similarity.
Subunit structure: Monomer. Interacts with SERPINE1/PAI1 and C1QBP
By similarity.
Subcellular location: Secreted › extracellular space.
Tissue specificity: Plasma.
Domain: The SMB domain mediates interaction with SERPINE1/PAI1
By similarity.
Post-translational modification: Sulfated on 2 tyrosine residues
By similarity.N- and O-glycosylated
By similarity.It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both.
Sequence similarities: Contains 4 hemopexin repeats.Contains 1 SMB (somatomedin-B) domain.
Research Articles on VTN
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Product Notes
The VTN vtn (Catalog #AAA634818) is a Protein produced from Vitronectin, from human plasma and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Vitronectin, Native, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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