Mouse Vascular endothelial growth factor C ELISA Kit | Vegfc elisa kit

Mouse Vascular endothelial growth factor C ELISA Kit

Cat. Num. AAA2884596

• Gene Names: Vegfc; VEGF-C; AW228853
• Reactivity: Mouse
• Synonyms: Vascular endothelial growth factor C; Mouse Vascular endothelial growth factor C ELISA Kit; VEGF-C; Flt4 ligand; Flt4-L; Vascular endothelial growth factor-related protein; VRP; Vegfc; Vegfc elisa kit

• Reactivity: Mouse
• Specificity: Recombinant and natural Mouse CHI3L3
• Sequence Length: 415

• Samples: Serum, Plasma, Tissue Homogenates, Cell Culture Supernates Or Other Biological Fluids
• Detection Range: 78-5000 pg/mL
• Intra-assay Precision: Intra-Assay CV: <=6.1%
• Inter-assay Precision: Inter-Assay CV: <=9.6%
• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for Vegfc elisa kit

Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 6678565
• NCBI GeneID: 22341
• NCBI Accession #: NP_033532.1
• NCBI GenBank Nucleotide #: NM_009506.2
• UniProt Accession #: P97953; Q543R6; C6F5S8; C6F5S9; C6F5T0
• Molecular Weight: 6,405 Da
• NCBI Official Full Name: vascular endothelial growth factor C
• NCBI Official Synonym Full Names: vascular endothelial growth factor C
• NCBI Official Symbol: Vegfc
• NCBI Official Synonym Symbols: VEGF-C; AW228853
• NCBI Protein Information: vascular endothelial growth factor C
• UniProt Protein Name: Vascular endothelial growth factor C
• Protein Family: Vascular endothelial growth factor
• UniProt Gene Name: Vegfc
• UniProt Synonym Gene Names: VEGF-C; Flt4-L; VRP
• UniProt Entry Name: VEGFC_MOUSE

Uniprot Description

VEGFC: Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. Homodimer; non-covalent and antiparallel. Spleen, lymph node, thymus, appendix, bone marrow, heart, placenta, ovary, skeletal muscle, prostate, testis, colon and small intestine and fetal liver, lung and kidney, but not in peripheral blood lymphocyte. Belongs to the PDGF/VEGF growth factor family.

Protein type: Cell cycle regulation; Secreted; Motility/polarity/chemotaxis; Cytokine; Secreted, signal peptide

Cellular Component: extracellular region; extracellular space; membrane

Molecular Function: chemoattractant activity; growth factor activity; protein binding; vascular endothelial growth factor receptor 3 binding

Biological Process: angiogenesis; cell differentiation; induction of positive chemotaxis; morphogenesis of embryonic epithelium; multicellular organismal development; negative regulation of blood pressure; negative regulation of cell proliferation; organ morphogenesis; positive chemotaxis; positive regulation of angiogenesis; positive regulation of blood vessel endothelial cell migration; positive regulation of cell division; positive regulation of cell proliferation; positive regulation of cell-matrix adhesion; positive regulation of epithelial cell proliferation; positive regulation of neuroblast proliferation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of protein amino acid autophosphorylation; positive regulation of protein secretion; regulation of vascular endothelial growth factor receptor signaling pathway; vascular endothelial growth factor receptor signaling pathway