Thyrotropin receptor (TSHR) Recombinant Protein | TSHR recombinant protein
Recombinant Dog Thyrotropin receptor (TSHR)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Thyrotropin receptor (TSHR); Recombinant Dog Thyrotropin receptor (TSHR); Recombinant Thyrotropin receptor (TSHR); Thyrotropin receptor; Thyroid-stimulating hormone receptor; TSH-R; TSHR recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
21-764
Sequence
GKGCPSPPCECHQEDDFRVTCKDIHRIPTLPPSTQTLKFIETQLKTIPSRAFSNLPNISRIYLSIDATLQRLESHSFYNLSKMTHIEIRNTRSLTSIDPDALKELPLLKFLGIFNTGLGVFPDVTKVYSTDVFFILEITDNPYMASIPANAFQGLCNETLTLKLYNNGFTSIQGHAFNGTKLDAVYLNKNKYLSAIDKDAFGGVYSGPTLLDVSYTSVTALPSKGLEHLKELIARNTWTLKKLPLSLSFLHLTRADLSYPSHCCAFKNQKKIRGILESLMCNESSIRSLRQRKSVNTLNGPFDQEYEEYLGDSHAGYKDNSQFQDTDSNSHYYVFFEEQEDEILGFGQELKNPQEETLQAFDSHYDYTVCGGNEDMVCTPKSDEFNPCEDIMGYKFLRIVVWFVSLLALLGNVFVLIVLLTSHYKLTVPRFLMCNLAFADFCMGMYLLLIASVDLYTHSEYYNHAIDWQTGPGCNTAGFFTVFASELSVYTLTVITLERWYAITFAMRLDRKIRLRHAYAIMVGGWVCCFLLALLPLVGISSYAKVSICLPMDTETPLALAYIILVLLLNIVAFIIVCSCYVKIYITVRNPQYNPGDKDTKIAKRMAVLIFTDFMCMAPISFYALSALMNKPLITVTNSKILLVLFYPLNSCANPFLYAIFTKAFQRDVFILLSKFGICKRQAQAYRGQRVSPKNSAGIQIQKVTRDMRQSLPNMQDEYELLENSHLTPNKQGQISKEYNQTVL
Sequence Length
764
Species
Canis familiaris (Dog) (Canis lupus familiaris)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
86,483 Da
NCBI Official Full Name
thyrotropin receptor
NCBI Official Symbol
TSHR
NCBI Protein Information
thyrotropin receptor; TSH-R; thyroid-stimulating hormone receptor
UniProt Protein Name
Thyrotropin receptor
Protein Family
UniProt Gene Name
TSHR
UniProt Synonym Gene Names
TSH-R
UniProt Entry Name
TSHR_CANFA
Uniprot Description
Function: Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5).
Subunit structure: Interacts (via the PDZ-binding motif) with SCRIB; regulates TSHR trafficking and function
By similarity.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Sequence similarities: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.Contains 6 LRR (leucine-rich) repeats.
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Product Notes
The TSHR tshr (Catalog #AAA950338) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 21-764. The amino acid sequence is listed below: GKGCPSPPCE CHQEDDFRVT CKDIHRIPTL PPSTQTLKFI ETQLKTIPSR AFSNLPNISR IYLSIDATLQ RLESHSFYNL SKMTHIEIRN TRSLTSIDPD ALKELPLLKF LGIFNTGLGV FPDVTKVYST DVFFILEITD NPYMASIPAN AFQGLCNETL TLKLYNNGFT SIQGHAFNGT KLDAVYLNKN KYLSAIDKDA FGGVYSGPTL LDVSYTSVTA LPSKGLEHLK ELIARNTWTL KKLPLSLSFL HLTRADLSYP SHCCAFKNQK KIRGILESLM CNESSIRSLR QRKSVNTLNG PFDQEYEEYL GDSHAGYKDN SQFQDTDSNS HYYVFFEEQE DEILGFGQEL KNPQEETLQA FDSHYDYTVC GGNEDMVCTP KSDEFNPCED IMGYKFLRIV VWFVSLLALL GNVFVLIVLL TSHYKLTVPR FLMCNLAFAD FCMGMYLLLI ASVDLYTHSE YYNHAIDWQT GPGCNTAGFF TVFASELSVY TLTVITLERW YAITFAMRLD RKIRLRHAYA IMVGGWVCCF LLALLPLVGI SSYAKVSICL PMDTETPLAL AYIILVLLLN IVAFIIVCSC YVKIYITVRN PQYNPGDKDT KIAKRMAVLI FTDFMCMAPI SFYALSALMN KPLITVTNSK ILLVLFYPLN SCANPFLYAI FTKAFQRDVF ILLSKFGICK RQAQAYRGQR VSPKNSAGIQ IQKVTRDMRQ SLPNMQDEYE LLENSHLTPN KQGQISKEYN QTVL. It is sometimes possible for the material contained within the vial of "Thyrotropin receptor (TSHR), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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