E3 ubiquitin-protein ligase TRIM33 (Trim33) Recombinant Protein | Trim33 recombinant protein
Recombinant Mouse E3 ubiquitin-protein ligase TRIM33 (Trim33) , partial
Gene Names
Trim33; Ecto; Tif1g; AI413936; 8030451N04Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
E3 ubiquitin-protein ligase TRIM33 (Trim33); Recombinant Mouse E3 ubiquitin-protein ligase TRIM33 (Trim33); partial; Trim33 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Length
1,125
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Trim33 recombinant protein
This protein is thought to be a transcriptional corepressor. However, molecules that interact with this protein have not yet been identified. The protein is a member of the tripartite motif family. This motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Three alternatively spliced transcript variants for this gene have been described, however, the full-length nature of one variant has not been determined.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
121,850 Da
NCBI Official Full Name
E3 ubiquitin-protein ligase TRIM33 isoform 2
NCBI Official Synonym Full Names
tripartite motif-containing 33
NCBI Official Symbol
Trim33
NCBI Official Synonym Symbols
Ecto; Tif1g; AI413936; 8030451N04Rik
NCBI Protein Information
E3 ubiquitin-protein ligase TRIM33
UniProt Protein Name
E3 ubiquitin-protein ligase TRIM33
Protein Family
UniProt Gene Name
Trim33
UniProt Synonym Gene Names
Kiaa1113; TIF1-gamma
Uniprot Description
Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway (). May act as a transcriptional repressor (). Inhibits the transcriptional response to TGF-beta/BMP signaling cascade (). Plays a role in the control of cell proliferation (). Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor. Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade) ().
Research Articles on Trim33
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Product Notes
The Trim33 trim33 (Catalog #AAA1485444) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "E3 ubiquitin-protein ligase TRIM33 (Trim33), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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