Western Blot (WB)
(Western blot detection of TIF1 gamma / TRIM33 in MCF7 and HelaNE cell lysates using TIF1 gamma / TRIM33 mouse mAb (1:1000 diluted).Predicted band size: 120KDa.Observed band size: 140KDa.)
Mouse anti-Human TIF1gamma/TRIM33 Monoclonal Antibody | anti-TIF1gamma/TRIM33 antibody
Anti-TIF1gamma/TRIM33 Mouse mAb
Western Blot (WB)
(Western blot detection of TIF1 gamma / TRIM33 in MCF7 and HelaNE cell lysates using TIF1 gamma / TRIM33 mouse mAb (1:1000 diluted).Predicted band size: 120KDa.Observed band size: 140KDa.)
Western Blot (WB)
(Western blot detection of TIF1 gamma / TRIM33 in MCF7 and HelaNE cell lysates using TIF1 gamma / TRIM33 mouse mAb (1:1000 diluted).Predicted band size: 120KDa.Observed band size: 140KDa.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is thought to be a transcriptional corepressor. However, molecules that interact with this protein have not yet been identified. The protein is a member of the tripartite motif family. This motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Three alternatively spliced transcript variants for this gene have been described, however, the full-length nature of one variant has not been determined. [provided by RefSeq, Jul 2008]
Uniprot Description
TIF1G: an atypical protein kinase that functions as a transcriptional repressor. Translocation with RET generates the TRIM33/RET (PTC7) oncogene. The protein is a member of the tripartite motif family. This motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Two splice variant isoforms have been described.
Protein type: ATYPICAL group; EC 6.3.2.-; EC 6.3.2.19; Kinase, protein; Ligase; Protein kinase, atypical; TIF1 family; Transcription, coactivator/corepressor; Ubiquitin conjugating system; Ubiquitin ligase
Chromosomal Location of Human Ortholog: 1p13.2
Cellular Component: intracellular membrane-bound organelle; nucleoplasm; nucleus
Molecular Function: protein binding; ubiquitin-protein ligase activity
Biological Process: negative regulation of BMP signaling pathway; negative regulation of transcription from RNA polymerase II promoter; protein ubiquitination; regulation of transforming growth factor beta receptor signaling pathway
Disease: Thyroid Carcinoma, Papillary
Research Articles on TIF1gamma/TRIM33
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Product Notes
The TIF1gamma/TRIM33 trim33 (Catalog #AAA475035) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-TIF1gamma/TRIM33 Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TIF1gamma/TRIM33 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1000. Researchers should empirically determine the suitability of the TIF1gamma/TRIM33 trim33 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TIF1gamma/TRIM33, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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