Testing Data
LIGHT recombinant protein
Murine LIGHT
Cross Reactivity: Human
Cross Reactivity: Human
Testing Data
Testing Data
NCBI and Uniprot Product Information
Uniprot Description
TNFSF14: Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus. Belongs to the tumor necrosis factor family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cytokine; Membrane protein, integral; Inhibitor
Cellular Component: extracellular space; membrane; plasma membrane; extracellular region; integral to membrane
Molecular Function: caspase inhibitor activity; cytokine activity; tumor necrosis factor receptor binding; receptor binding
Biological Process: release of cytoplasmic sequestered NF-kappaB; T cell costimulation; immune response; negative regulation of caspase activity; positive regulation of myoblast differentiation
Research Articles on LIGHT
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Product Notes
The LIGHT tnfsf14 (Catalog #AAA695758) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Murine LIGHT reacts with Species Reactivity: Mouse Cross Reactivity: Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MRLHQRLGD IVAHLPDGG KGSWEKLIQ DQRSHQANP AAHLTGANA SLIGIGGPL LWETRLGLA FLRGLTYHD GALVTMEPG YYYVYSKVQ LSGVGCPQG LANGLPITH GLYKRTSRY PKELELLVS RRSPCGRAN SSRVWWDSS FLGGVVHLE AGEEVVVRV PGNRLVRPR DGTRSYFGA FMV. It is sometimes possible for the material contained within the vial of "LIGHT, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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