Western Blot (WB)
(Western Blot analysis of RBPJL expression in transfected 293T cell line by RBPJL polyclonal antibody. Lane 1: RBPJL transfected lysate (56.8kD). Lane 2: Non-transfected lysate. )
Rabbit anti-Human RBPJ Polyclonal Antibody | anti-RBPJ antibody
RBPJ (IGKJRB, IGKJRB1, RBPJK, RBPSUH, Recombining Binding Protein Suppressor of Hairless, CBF-1, J kappa-recombination Signal-binding Protein, RBP-J kappa, Renal Carcinoma Antigen NY-REN-30, MGC61669) (FITC)
Gene Names
RBPJL; RBPL; SUHL; RBPSUHL
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
RBPJ; Polyclonal Antibody; RBPJ (IGKJRB; IGKJRB1; RBPJK; RBPSUH; Recombining Binding Protein Suppressor of Hairless; CBF-1; J kappa-recombination Signal-binding Protein; RBP-J kappa; Renal Carcinoma Antigen NY-REN-30; MGC61669) (FITC); anti-RBPJ antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human RBPJL.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Sequence Length
2630
Applicable Applications for anti-RBPJ antibody
Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length human RBPJL, aa1-517 (NP_055091.2).
Immunogen Sequence
MDPAGAADPSVPPNPLTHLSLQDRSEMQLQSEADRRSLPGTWTRSSPEHTTILRGGVRRCLQQQCEQTVRILHAKVAQKSYGNEKRFFCPPPCVYLSGPGWRVKPGQDQAHQAGETGPTVCGYMGLDSASGSATETQKLNFEQQPDSREFGCAKTLYISDADKRKHFRLVLRLVLRGGRELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGAFVASARQWAAFTLHLADGHSAQGDFPPREGYVRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPGSPPGGGGTYLCLATEKVVQFQASPCPKEANRALLNDSSCWTIIGTESVEFSFSTSLACTLEPVTPVPLISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMYRSPRSLVCVVPDVAAFCSDWRWLRAPITIPMSLVRADGLFYPSAFSFTYTPEYSVRPGHPGVPEPATDADALLESIHQEFTRTNFHLFIQT
Conjugate
FITC
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot analysis of RBPJL expression in transfected 293T cell line by RBPJL polyclonal antibody. Lane 1: RBPJL transfected lysate (56.8kD). Lane 2: Non-transfected lysate. )
Western Blot (WB)
(Western Blot analysis of RBPJL expression in transfected 293T cell line by RBPJL polyclonal antibody. Lane 1: RBPJL transfected lysate (56.8kD). Lane 2: Non-transfected lysate. )
Related Product Information for anti-RBPJ antibody
Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.
Product Categories/Family for anti-RBPJ antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
Homo sapiens recombination signal binding protein for immunoglobulin kappa J region-like (RBPJL), mRNA
NCBI Official Synonym Full Names
recombination signal binding protein for immunoglobulin kappa J region like
NCBI Official Symbol
RBPJL
NCBI Official Synonym Symbols
RBPL; SUHL; RBPSUHL
NCBI Protein Information
recombining binding protein suppressor of hairless-like protein
Protein Family
NCBI Description
This gene encodes a member of the suppressor of hairless protein family. A similar protein in mouse is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signaling pathway transcription factor recombining binding protein J. The mouse protein has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Research Articles on RBPJ
Similar Products
Product Notes
The RBPJ (Catalog #AAA6392213) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RBPJ (IGKJRB, IGKJRB1, RBPJK, RBPSUH, Recombining Binding Protein Suppressor of Hairless, CBF-1, J kappa-recombination Signal-binding Protein, RBP-J kappa, Renal Carcinoma Antigen NY-REN-30, MGC61669) (FITC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RBPJ can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the RBPJ for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RBPJ, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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