Human Tumor necrosis factor-inducible gene 6 ELISA Kit | TNFAIP6 elisa kit
Human Tumor necrosis factor-inducible gene 6 protein ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.[provided by RefSeq, Dec 2010]
Uniprot Description
TNFAIP6: Possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis.
Chromosomal Location of Human Ortholog: 2q23.3
Cellular Component: extracellular region
Molecular Function: protein binding
Biological Process: cell-cell signaling; inflammatory response; negative regulation of inflammatory response; neutrophil degranulation; signal transduction
Research Articles on TNFAIP6
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Product Notes
The Human TNFAIP6 tnfaip6 (Catalog #AAA9425929) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9425929 ELISA Kit recognizes Human TNFAIP6. It is sometimes possible for the material contained within the vial of "Tumor necrosis factor-inducible gene 6, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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