Transmembrane protein 165 (Tmem165) Recombinant Protein | Tmem165 recombinant protein
Recombinant Mouse Transmembrane protein 165 (Tmem165)
NCBI and Uniprot Product Information
Uniprot Description
TMEM165: Defects in TMEM165 are the cause of congenital disorder of glycosylation type 2K (CDG2K). An autosomal recessive disorder with a variable phenotype. Affected individuals show psychomotor retardation and growth retardation, and most have short stature. Other features include dysmorphism, hypotonia, eye abnormalities, acquired microcephaly, hepatomegaly, and skeletal dysplasia. Congenital disorders of glycosylation are caused by a defect in glycoprotein biosynthesis and characterized by under- glycosylated serum glycoproteins and a wide variety of clinical features. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions. Belongs to the GDT1 family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Cellular Component: Golgi apparatus; membrane; intracellular membrane-bound organelle; lysosomal membrane; lysosome; integral to membrane; trans-Golgi network membrane; endosome membrane; endosome
Biological Process: cellular calcium ion homeostasis; protein amino acid N-linked glycosylation; Golgi calcium ion transport
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Product Notes
The Tmem165 tmem165 (Catalog #AAA954595) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-323. The amino acid sequence is listed below: MAAAARGSGR APTRRLLVLL LLQLLWAPAG VRAGPEEDLS HRNQEPPAPA QQLQPQPAAV QGLEPARAEK GLTPVAPVHT NKEDAAAQTN LGFIHAFVAA ISVIIVSELG DKTFFIAAIM AMRYNRLTVL AGAMLALALM TCLSVLFGYA TTVIPRVYTY YVSTALFAIF GIRMLREGLK MSPDEGQEEL EEVQAELKKK DEEFQRTKLL NGPDVETGTS TAIPQKKWLH FISPIFVQAL TLTFLAEWGD RSQLTTIVLA AREDPYGVAV GGTVGHCLCT GLAVIGGRMI AQKISVRTVT IIGGIVFLAF AFSALFISPE SGF. It is sometimes possible for the material contained within the vial of "Transmembrane protein 165 (Tmem165), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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