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Testing Data

TROP-2/TACSTD2 Recombinant Protein | TROP-2 recombinant protein

Human CellExp TROP-2/TACSTD2; Human recombinant

Gene Names
TACSTD2; EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1
Applications
SDS-Page
Purity
> 95%
Synonyms
TROP-2/TACSTD2; Human CellExp TROP-2/TACSTD2; Human recombinant; TACSTD2; GA733-1; M1S1; TROP2; TROP-2 recombinant protein
Ordering
For Research Use Only!
Host
HEK 293 cells
Source: Human
Purity/Purification
> 95%
Form/Format
Lyophilized from 0.22 mum filtered solution in PBS; pH 7.4. Normally Trehalose is added as protectant before lyophilization.
Sequence Length
323
Applicable Applications for TROP-2 recombinant protein
SDS-PAGE
Endotoxin Level
< 1.0 EU per/mug
Reconstitution
Reconstitute in sterile deionized water to the desired protein concentration.
Preparation and Storage
Store at -20 degree C for 12 months.
Centrifuge the vial prior to opening.

Testing Data

Testing Data
Related Product Information for TROP-2 recombinant protein
Tumor-associated calcium signal transducer 2 (TACSTD2) is also known as Cell surface glycoprotein Trop-2; Membrane component chromosome 1 surface marker 1 (M1S1); Pancreatic carcinoma marker protein GA733-1; which belongs to the EPCAM family. TACSTD2 contains one thyroglobulin type-1 domain. TACSTD2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. TACSTD2 transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of TACSTD2 result in gelatinous drop-like corneal dystrophy; an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28.7 kDa
NCBI Official Full Name
tumor-associated calcium signal transducer 2
NCBI Official Synonym Full Names
tumor associated calcium signal transducer 2
NCBI Official Symbol
TACSTD2
NCBI Official Synonym Symbols
EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1
NCBI Protein Information
tumor-associated calcium signal transducer 2
UniProt Protein Name
Tumor-associated calcium signal transducer 2
UniProt Gene Name
TACSTD2
UniProt Synonym Gene Names
GA733-1; M1S1; TROP2

NCBI Description

This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009]

Uniprot Description

TACSTD2: May function as a growth factor receptor. Defects in TACSTD2 are the cause of gelatinous drop-like corneal dystrophy (GDLD); also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment. Belongs to the EPCAM family.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 1p32.1

Cellular Component: basal plasma membrane; cytosol; extracellular space; integral to plasma membrane; lateral plasma membrane; membrane; nucleus

Molecular Function: protein binding; receptor activity

Biological Process: cell proliferation; cell surface receptor linked signal transduction; negative regulation of stress fiber formation

Disease: Corneal Dystrophy, Gelatinous Drop-like

Research Articles on TROP-2

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Product Notes

The TROP-2 tacstd2 (Catalog #AAA847060) is a Recombinant Protein produced from HEK 293 cells Source: Human and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TROP-2/TACSTD2 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the TROP-2 tacstd2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TROP-2/TACSTD2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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