Synaptotagmin-2 Blocking Peptide | SYT2 blocking peptide
Synaptotagmin-2 Immunizing Peptide
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a synaptic vesicle membrane protein. The encoded protein is thought to function as a calcium sensor in vesicular trafficking and exocytosis. Mutations in this gene are associated with myasthenic syndrome, presynaptic, congenital, with or without motor neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Uniprot Description
SYT2: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. Belongs to the synaptotagmin family.
Protein type: Vesicle; Membrane protein, integral; Lipid-binding; Calcium-binding
Chromosomal Location of Human Ortholog: 1q32.1
Cellular Component: cell junction; cytosol; integral to membrane; intracellular membrane-bound organelle; plasma membrane; synaptic vesicle membrane
Molecular Function: calcium ion binding; calcium-dependent phospholipid binding; clathrin binding; inositol 1,3,4,5 tetrakisphosphate binding; protein binding; syntaxin binding
Biological Process: calcium ion-dependent exocytosis of neurotransmitter; regulation of calcium ion-dependent exocytosis; synaptic vesicle endocytosis; vesicle fusion
Disease: Myasthenic Syndrome, Presynaptic, Congenital, With Or Without Motor Neuropathy
Research Articles on SYT2
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Product Notes
The SYT2 syt2 (Catalog #AAA427724) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The Synaptotagmin-2 Immunizing Peptide reacts with Human, Mouse, Rat, Cow and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-KPEEEVDA LLGKNK. It is sometimes possible for the material contained within the vial of "Synaptotagmin-2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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