Roscovitine Small Molecule

Roscovitine

Cat. Num. AAA808172

• Purity: >=95% (HPLC, TLC)
• Synonyms: Roscovitine; p34/cdc2 inhibitor; 2-(R)-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol; 6-Benzylamino-2-(R)-[(1-ethyl)-2-hydroxyethylamino]-9-isopropylpurine; 2(R)-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine; Roscovitine small molecule

• Host: Synthetic
• Purity/Purification: >=95% (HPLC, TLC)
• Form/Format: White to off-white solid

• Solubility: Soluble in DMSO
• CAS Number: 186692-46-6
• Molecular Formula: C19H26N6O
• SMILES: [C@H](NC2=NC1=C(N=C[N]1C(C)C)C(=N2)NCC3=CC=CC=C3)(CO)CC
• InChI: 1S/C19H26N6O/c1-4-15(11-26)22-19-23-17(20-10-14-8-6-5-7-9-14)16-18(24-19)25(12-21-16)13(2)3/h5-9,12-13,15,26H,4,10-11H2,1-3H3,(H2,20,22,23,24)/t15-/m1/s1
• InChI Key: BTIHMVBBUGXLCJ-OAHLLOKOSA-N
• PubChem CID: 160355
• Preparation and Storage: Store at -20 degree C.

Chemical Structure

(Chemical structure of Roscovitine (SIH-472), a p34/cdc2 inhibitor. CAS #: 186692-46-6. Molecular Formula: C19H26N6O. Molecular Weight: 354.4 g/mol.)

Related Product Information for Roscovitine small molecule

Roscovitine is a potent and selective inhibitor of cyclin-dependent kinases (CDKs). It is specifically selective for CDK1/cyclin B kinase, CDK2 and CDK5/p35. It inhibits M phase promoting factor kinase activity and affects calcium channel gating.

Product Categories/Family for Roscovitine small molecule

Small Molecules; Inhibitor; Cell Signaling

References

1. De Azevedo, et al. (1997) Eur. J. Biochem. 243(1-2): 518-526.