Chemical Structure
(Chemical structure of NVPBEZ235 (SIH-465), a PI 3-kinase inhibitor. CAS #: 915019-65-7. Molecular Formula: C30H23N5O. Molecular Weight: 469.5 g/mol.)
NVPBEZ235 small molecule
NVPBEZ235
Purity
>=97%
Synonyms
NVPBEZ235; PI 3-kinase inhibitor; NVPBEZ235 small molecule
Host
Synthetic
Purity/Purification
>=97%
Form/Format
Crystalline solid
Solubility
Soluble in chloroform (1 mg/ml), 1-methyl-2-pyrrolidnone (2 mg/ml at 75 degree C), DMSO (1.33 mg/ml), and DMF (10 mg/ml at 75 degree C)
CAS Number
915019-65-7
Molecular Formula
C30H23N5O
SMILES
CC(C)(C#N)C1=CC=C(C=C1)N2C3=C4C=C(C=CC4=NC=C3N(C2=O)C)C5=CC6=CC=CC=C6N=C5
InChI
1S/C30H23N5O/c1-30(2,18-31)22-9-11-23(12-10-22)35-28-24-15-19(21-14-20-6-4-5-7-25(20)32-16-21)8-13-26(24)33-17-27(28)34(3)29(35)36/h4-17H,1-3H3
InChI Key
JOGKUKXHTYWRGZ-UHFFFAOYSA-N
PubChem CID
11977753
Preparation and Storage
Store at -20 degree C.
Chemical Structure
(Chemical structure of NVPBEZ235 (SIH-465), a PI 3-kinase inhibitor. CAS #: 915019-65-7. Molecular Formula: C30H23N5O. Molecular Weight: 469.5 g/mol.)
Chemical Structure
(Chemical structure of NVPBEZ235 (SIH-465), a PI 3-kinase inhibitor. CAS #: 915019-65-7. Molecular Formula: C30H23N5O. Molecular Weight: 469.5 g/mol.)
Related Product Information for NVPBEZ235 small molecule
NVPBEZ235 is a specific PI 3-kinase (PI3K) tyrosine kinase inhibitor, which shows dual PI3K/mTOR inhibition. NVPBEZ235 has also been shown to inhibit ATR. It has demonstrated antiproliferative activity against tumor cell lines in animal models of cancer.
Product Categories/Family for NVPBEZ235 small molecule
References
1. Yasumizu Y., et al. (2014) J. Urology. 191(1): 227-234. 2. Shortt J., et al. (2013) Blood. 121(15): 2964-2974.
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Product Notes
The NVPBEZ235 (Catalog #AAA808165) is a Small Molecule produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "NVPBEZ235, Small Molecule" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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