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Chemical Structure (Chemical structure of DMPQ Dihydrochloride (SIH-441), a PDGFRbeta kinase inhibitor. CAS #: 137206-97-4. Molecular Formula: C16H16ClN2O2. Molecular Weight: 339.2 g/mol.)

DMPQ small molecule

DMPQ Dihydrochloride

Purity
>=98% (HPLC)
Synonyms
DMPQ; DMPQ Dihydrochloride; PDGFRbeta kinase inhibitor; 5; 7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride; DMPQ small molecule
Ordering
For Research Use Only!
Host
Synthetic
Purity/Purification
>=98% (HPLC)
Form/Format
White to beige solid
Sequence Length
112
Solubility
Soluble to 100 mM in water
CAS Number
137206-97-4
Molecular Formula
C16H16ClN2O2
SMILES
C1=CC(=CC=N1)C2=CC3=C(N=C2)C=C(C=C3OC)OC
InChI
1S/C16H14N2O2.2ClH/c1-19-13-8-15-14(16(9-13)20-2)7-12(10-18-15)11-3-5-17-6-4-11;;/h3-10H,1-2H3;2*1H
InChI Key
YBBAOKYVJCNJIV-UHFFFAOYSA-N
PubChem CID
45073427
Preparation and Storage
Store at -20 degree C.

Chemical Structure

(Chemical structure of DMPQ Dihydrochloride (SIH-441), a PDGFRbeta kinase inhibitor. CAS #: 137206-97-4. Molecular Formula: C16H16ClN2O2. Molecular Weight: 339.2 g/mol.)

Chemical Structure (Chemical structure of DMPQ Dihydrochloride (SIH-441), a PDGFRbeta kinase inhibitor. CAS #: 137206-97-4. Molecular Formula: C16H16ClN2O2. Molecular Weight: 339.2 g/mol.)
Related Product Information for DMPQ small molecule
DMPQ dihydrochloride is a potent and selective inhibitor of human vascular beta-type platelet derived growth factor receptor tyrosine kinase (PDGFRbeta). It displays > 100-fold selectivity over EGFR tyrosine kinase, erbB2, p56, protein kinase A and protein kinase C.
References
1. Dolle R.E., et al. (1994) J. Med. Chem. 37(17): 2627-2629.

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
339.2
NCBI Official Full Name
dmpQ
UniProt Protein Name
DmpQ
UniProt Gene Name
dmpQ

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Product Notes

The DMPQ dmpq (Catalog #AAA808141) is a Small Molecule produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "DMPQ, Small Molecule" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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