Rabbit anti-Human MAPK4 Polyclonal Antibody | anti-MAPK4 antibody

MAPK4 Rabbit pAb

Cat. Num. AAA4754674

• Gene Names: MAPK4; ERK4; ERK-4; PRKM4; p63MAPK; p63-MAPK
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity purified
• Synonyms: MAPK4; Polyclonal Antibody; MAPK4 Rabbit pAb; ERK4; ERK-4; PRKM4; p63MAPK; p63-MAPK; anti-MAPK4 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Purity/Purification: Affinity purified
• Form/Format: -20 degree C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

• Applicable Applications for anti-MAPK4 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
• Application Notes: WB: 1:500-1:2000
• Immunogen: Synthetic peptide of human MAPK4
• Conjugation: Unconjugated
• Molecular Function: Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus and phosphorylate nuclear targets. Alternative splicing results in multiple transcript variants.
• Modification: Unmodified
• Cell Position: Cytoplasm, Nucleus
• Preparation and Storage: Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-4: 293T cell, Human heart tissue, Raji and LNCAP cell lysates, Primary antibody: 160319(MAPK4 Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds)

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 160319(MAPK4 Antibody) at dilution 1/35. (Original magnification: ×200))

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 160319(MAPK4 Antibody) at dilution 1/35. (Original magnification: ×200))

Product Categories/Family for anti-MAPK4 antibody

Primary antibody

NCBI and Uniprot Product Information

• NCBI GI #: 89276769
• NCBI GeneID: 5596
• NCBI Accession #: NP_002738
• NCBI GenBank Nucleotide #: NM_002747
• UniProt Accession #: P31152; Q0VG04; A1A4C4
• Molecular Weight: 65,922 Da
• NCBI Official Full Name: mitogen-activated protein kinase 4 isoform 1
• NCBI Official Synonym Full Names: mitogen-activated protein kinase 4
• NCBI Official Symbol: MAPK4
• NCBI Official Synonym Symbols: ERK4; ERK-4; PRKM4; p63MAPK; p63-MAPK
• NCBI Protein Information: mitogen-activated protein kinase 4; Erk3-related; MAP kinase isoform p63; MAPK 4; extracellular signal-regulated kinase 4
• UniProt Protein Name: Mitogen-activated protein kinase 4
• UniProt Gene Name: MAPK4
• UniProt Synonym Gene Names: ERK4; PRKM4; MAP kinase 4; MAPK 4; ERK-4; p63-MAPK
• UniProt Entry Name: MK04_HUMAN

Uniprot Description

ERK4: a protein kinase of the MAPK family. Phosphorylation and activations leads to translocation into the nucleus where it phosphorylates nuclear targets.

Protein type: Protein kinase, Ser/Thr (non-receptor); Protein kinase, CMGC; Kinase, protein; EC 2.7.11.24; CMGC group; MAPK family; MAPK/ERK subfamily; ERK subfamily

Chromosomal Location of Human Ortholog: 18q21.1

Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus

Molecular Function: ATP binding; MAP kinase activity; protein binding; protein heterodimerization activity; protein homodimerization activity; protein kinase binding; protein serine/threonine kinase activity

Biological Process: cell cycle; MAPKKK cascade; protein amino acid phosphorylation