Mouse SH3 and PX domains 2B ELISA Kit | SH3PXD2B elisa kit
Mouse SH3 and PX domain-containing protein 2B, SH3PXD2B ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
SH3PXD2B: Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation. Defects in SH3PXD2B are the cause of Frank-Ter Haar syndrome (FTHS). It is a syndrome characterized by brachycephaly, wide fontanels, prominent forehead, hypertelorism, prominent eyes, macrocornea with or without glaucoma, full cheeks, small chin, bowing of the long bones and flexion deformity of the fingers. Belongs to the SH3PXD2 family.
Protein type: Lipid-binding
Cellular Component: cell projection; cytoplasm; podosome; cell junction
Molecular Function: phosphatidylinositol-5-phosphate binding; SH2 domain binding; phosphoinositide binding; phosphatidylinositol 3-phosphate binding
Biological Process: extracellular matrix disassembly; eye development; heart development; superoxide metabolic process; positive regulation of fat cell differentiation; cell differentiation; skeletal development
Research Articles on SH3PXD2B
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Product Notes
The Mouse SH3PXD2B sh3pxd2b (Catalog #AAA9333121) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9333121 ELISA Kit recognizes Mouse SH3PXD2B. It is sometimes possible for the material contained within the vial of "SH3 and PX domains 2B, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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