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Gene Name
Isotype
Host
Application
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2980 results for " Bone Growth" - showing 100-150
Activity Data
(Platelet Derived Growth Factor Subunit A (PDGFA) is a member of Platelet-derived growth factor (PDGF) family which plays a significant role in blood vessel formation, the growth of blood vessels from already-existing blood vessel tissue, mitogenesis, i.e. proliferation, of mesenchymal cells such as fibroblasts, osteoblasts, tenocytes, vascular smooth muscle cells and mesenchymal stem cells as well as chemotaxis, the directed migration, of mesenchymal cells. Besides, Platelet Derived Growth Factor Receptor Alpha (PDGFRa) has been identified as an interactor of PDGFA, thus a binding ELISA assay was conducted to detect the interaction of recombinant human PDGFA and recombinant human PDGFRa. Briefly, PDGFA were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100mul were then transferred to PDGFRa-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-PDGFA pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of PDGFA and PDGFRa was shown in Figure 1, and this effect was in a dose dependent manner.Figure. The binding activity of PDGFA with PDGFRa.)
Platelet Derived Growth Factor Subunit A (PDGFA), Active Protein (Cat# AAA2105097)
Full Name
Active Platelet Derived Growth Factor Subunit A (PDGFA)
Gene Names
PDGFA; PDGF1; PDGF-A
Applications
Cell Culture, Activity Assays
Purity
> 90%
Pricing
$225/0.01 mg | $475/0.05 mg | $735/0.1 mg | $910/0.2 mg | $1,775/0.5 mg | $2,625/1 mg | $6,415/5 mg
Western Blot (WB)
(Western Blot of recombinant fragment of CD117 using CD117 Monoclonal Antibody (KIT/983).)
CD117 / c-Kit, Monoclonal Antibody (Cat# AAA439563)
Full Name
CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) Mouse Monoclonal Antibody
Gene Names
KIT; PBT; SCFR; C-Kit; CD117
Reactivity
Human
Applications
FC/FACS, IF, IHC
Pricing
$390/0.1 mg (With BSA & Azide at 0.2mg/mL) | $390/0.1 mg (Without BSA & Azide at 1mg/mL) | $215/0.02 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (Without BSA & Azide at 1mg/mL)
Testing Data
(Immunofluorescence staining of mouse lymph node cryosection with Rat anti Mouse CD11b, clone 5C6 (MBS216530), green in A and Rat anti Mouse CD8, clone YTS105.18 , red in B. C is the merged image with nuclei counterstained blue using DAPI. Low power)
CD11b, Monoclonal Antibody (Cat# AAA216532)
Full Name
RAT ANTI MOUSE CD11b:FITC
Gene Names
Itgam; CR3; CR3A; MAC1; Cd11b; Ly-40; Mac-1; Mac-1a; CD11b/CD18; F730045J24Rik
Applications
FC/FACS
Pricing
$210/0.025 mg | $800/5x0.025 mg
Western Blot (WB)
(GDF15 Antibody (N-term) (MBS9213643) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the GDF15 antibody detected the GDF15 protein (arrow).)
GDF15, Polyclonal Antibody (Cat# AAA9213643)
Full Name
GDF15 Antibody (N-term)
Gene Names
GDF15; PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15
Reactivity
Human
Applications
WB, IHC, FC, EIA
Pricing
$405/0.4 mL | $185/0.08 mL | $1,585/5x0.4 mL
Western Blot (WB)
(Western Blot: Sample: Mouse Testis Tissue.)
Bone Morphogenetic Protein 15, Polyclonal Antibody (Cat# AAA2026132)
Full Name
Polyclonal Antibody to Bone Morphogenetic Protein 15 (BMP15)
Gene Names
Bmp15; Bmp-15; C86824; C87336; GDF-9B; AU015375; AU018861; AU021453
Reactivity
Mouse
Applications
WB, ICC, IHC, EIA
Purity
Affinity Chromatography
Pricing
$165/0.1 mL | $210/0.2 mL | $355/0.5 mL | $435/1 mL | $1,240/5x1 mL
Testing Data
(Immunofluorescence staining of mouse lymph node cryosection with Rat anti Mouse CD11b, clone 5C6 (MBS216530), green in A and Rat anti Mouse CD8, clone YTS105.18 , red in B. C is the merged image with nuclei counterstained blue using DAPI. Low power)
CD11b, Monoclonal Antibody (Cat# AAA216531)
Full Name
RAT ANTI MOUSE CD11b:FITC
Gene Names
Itgam; CR3; CR3A; MAC1; Cd11b; Ly-40; Mac-1; Mac-1a; CD11b/CD18; F730045J24Rik
Applications
FC/FACS
Pricing
$460/0.1 mg | $1,910/5x0.1 mg
Immunofluorescence (IF)
(MBS9600902 staining NIH-3T3 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37 degree C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.)
Met, Polyclonal Antibody (Cat# AAA9600902)
Full Name
Phospho-Met (Tyr1349) Antibody
Gene Names
MET; HGFR; AUTS9; RCCP2; c-Met; DFNB97
Reactivity
Human, Mouse, Rat
Applications
WB, IF, ICC, EIA
Purity
From purified rabbit serum by affinity purification via sequential chromatography on phospho-and non-phospho-peptide affinity columns.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Activity Data
(GDF9 (Growth/differentiation factor 9) is an oocyte derived growth factora which belongs to the transforming growth factor-beta (TGFbeta) superfamily. GDF9 is required for ovarian folliculogenesis and promotes primordial follicle development. S100A8 has been identified as an interactor of GDF9 through two-hybrid assay, thus a binding ELISA assay was conducted to detect the interaction of recombinant human GDF9 and recombinant human S100A8. Briefly, GDF9 were diluted serially in PBS, with 0.01%BSA (pH 7.4). Duplicate samples of 100uL were then transferred to S100A8-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-GDF9 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of of GDF9 and S100A8 was shown in Figure 1, and this effect was in a dose dependent manner.)
Growth Differentiation Factor 9 (GDF9), Active Protein (Cat# AAA2097272)
Full Name
Active Growth Differentiation Factor 9 (GDF9)
Reactivity
Human
Applications
Cell culture, Activity Assays
Purity
> 90%
Pricing
$240/0.01 mg | $520/0.05 mg | $800/0.1 mg | $995/0.2 mg | $1,940/0.5 mg | $2,875/1 mg | $7,030/5 mg
Flow Cytometry (FC/FACS)
( Flow-cytometry using the anti-Fas antibody R-125224 (Ab00802) Jurkat cells were fixed using 2% PFA, permeabilised using 0.5% Triton and stained with unimmunized rabbit IgG antibody (MOPC-21; isotype control, black line) or the rabbit IgG-chimeric version of R-125224 (Ab00802-23.0, blue line) at a dilution of 1:100 for 1h at RT. After washing, bound antibody was detected using a goat anti-rabbit IgG AlexaFluor® 488 antibody at a dilution of 1:1000 and cells analyzed using a FACSCanto flow-cytometer.)
Fas, Monoclonal Recombinant Antibody (Cat# AAA488362)
Full Name
Anti-Fas [R-125224]
Gene Names
FAS; APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6
Reactivity
Human
Applications
EIA, FC/FACS
Purity
Protein A Affinity Purified
Pricing
$495/0.2 mg | $2,025/5x0.2 mg
Testing Data
(Published customer image:IL-4 DC and IL-10 DC exhibit no obvious differences in their phenotype. IL-4 DC and IL-10 DC and mature splenic DC (sDC) coexpressed Ox62 and CD68, whereas macrophages generated in the presence of M-CSF (5 ug/ml) were only positive for CD68. Broken lines indicate background staining obtained using an irrelevant isotype control. The first number represents the percentage of cells staining positive for the indicated marker and the second number represents the mean fluorescence intensity. The results shown are representative for 4 independent flow cytometric analyses.From:BMC Res Notes. 2009 Jan 23;2:12.)
OX-62, Monoclonal Antibody (Cat# AAA212002)
Full Name
MOUSE ANTI RAT OX-62
Applications
FC/FACS, IP, WB
Pricing
$490/0.25 mg | $2,050/5x0.25 mg
Activity Data
(Figure. The binding activity of COL6a1 with PDGFA.Collagen alpha-1(VI) chain (COL6a1) is a protein that in humans, the collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Besides, Platelet-derived growth factor subunit A (PDGFA) has been identified as an interactor of COL6A1, thus a binding ELISA assay was conducted to detect the interaction of recombinant human COL6a1 and recombinant human PDGFA. Briefly, COL6a1 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to PDGFA-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-COL6a1 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of COL6a1 and PDGFA was shown in Figure 1, and this effect was in a dose dependent manner.)
Collagen Type VI Alpha 1 (COL6a1), Active Protein (Cat# AAA2105169)
Full Name
Active Collagen Type VI Alpha 1 (COL6a1)
Gene Names
Col6a1; Col6a-1; AI747156
Applications
Cell Culture, Activity Assays
Purity
> 95%
Pricing
$225/0.01 mg | $490/0.05 mg | $755/0.1 mg | $940/0.2 mg | $1,830/0.5 mg | $2,710/1 mg | $6,620/5 mg
BMP-3, Active Protein (Cat# AAA691619)
Full Name
Human BMP-3
Gene Names
BMP3; BMP-3A
Reactivity
Human
Purity
>95% by SDS-PAGE & HPLC analyses
Pricing
$250/0.01 mg | $395/0.05 mg | $1,565/5x0.05 mg
Immunohistochemistry (IHC)
(Formalin-fixed, paraffin-embedded human Prostate stained with Decorin Mouse Monoclonal Antibody (DCN/3523).)
Decorin, Monoclonal Antibody (Cat# AAA4380832)
Full Name
Decorin
Gene Names
DCN; CSCD; PG40; PGII; PGS2; DSPG2; SLRR1B
Reactivity
Human
Applications
IHC
Purity
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Pricing
$390/0.1 mg (With BSA & Azide at 0.2mg/mL) | $390/0.1 mg (Without BSA & Azide at 1mg/mL) | $215/0.02 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (Without BSA & Azide at 1mg/mL)
Immunofluorescence (IF)
(MBS9605551 staining 293 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37 degree C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.)
GDF15, Polyclonal Antibody (Cat# AAA9605551)
Full Name
GDF15 Antibody
Gene Names
GDF15; PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15
Reactivity
Human
Applications
WB, IF, ICC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Western Blot (WB)
(Western blot analysis of FLT3 in lysates of COS7 , using FLT3 Antibody.)
FLT3, Polyclonal Antibody (Cat# AAA9611086)
Full Name
FLT3 Antibody
Gene Names
FLT3; FLK2; STK1; CD135; FLK-2
Reactivity
Human, Mouse
Predicted: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
Predicted: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
Applications
WB, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Pricing
$245/0.05 mL | $305/0.1 mL | $365/0.2 mL | $1,495/5x0.2 mL
Western Blot (WB)
(Western Blot: Sample: Lane1: Human hela Cells; Lane2: Human HepG2 Cells; Lane3: Mouse Heart Tissue.)
Growth Differentiation Factor 2, Polyclonal Antibody (Cat# AAA2026717)
Full Name
Polyclonal Antibody to Growth Differentiation Factor 2 (GDF2)
Gene Names
GDF2; BMP9; HHT5; BMP-9
Reactivity
Human
Applications
WB, ICC, IHC, EIA
Purity
Affinity Chromatography
Pricing
$160/0.1 mL | $195/0.2 mL | $320/0.5 mL | $405/1 mL | $1,160/5x1 mL
Typical Testing Data/Standard Curve (for reference only)
GDF11, ELISA Kit (Cat# AAA2502734)
Full Name
Human GDF11 (Growth Differentiation Factor 11) ELISA Kit
Gene Names
GDF11; BMP11; BMP-11
Reactivity
Human
Pricing
$440/48-Strip-Wells | $525/96-Strip-Wells | $2,215/5x96-Strip-Wells | $3,965/10x96-Strip-Wells | $250/24-Strip-Wells
Western Blot (WB)
(Western blot analysis GDF6 using HeLa whole cell lysates)
GDF6, Polyclonal Antibody (Cat# AAA9609861)
Full Name
GDF6 Antibody
Gene Names
GDF6; KFM; KFS; KFS1; KFSL; SGM1; BMP13; CDMP2; SYNS4; BMP-13
Reactivity
Human, Mouse, Rat
Applications
WB, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Immunohistochemistry (IHC)
(MBS9607664 at 1/100 staining Mouse colon tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)
VEGFC, Polyclonal Antibody (Cat# AAA9607664)
Full Name
VEGFC Antibody
Gene Names
VEGFC; VRP; Flt4-L; LMPH1D
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Western Blot (WB)
(Western blot analysis of BMP9 using HeLa whole lysates.)
BMP9, Polyclonal Antibody (Cat# AAA9608335)
Full Name
BMP9 Antibody
Gene Names
GDF2; BMP9; HHT5; BMP-9
Reactivity
Human, Mouse, Rat
Applications
WB, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Western Blot (WB)
(Western Blot: Sample: Lane1: Mouse Brain Tissue; Lane2: Mouse Kidney Tissue.)
Growth Differentiation Factor 6, Polyclonal Antibody (Cat# AAA2027804)
Full Name
Polyclonal Antibody to Growth Differentiation Factor 6 (GDF6)
Gene Names
GDF6; KFM; KFS; KFS1; KFSL; SGM1; BMP13; CDMP2; BMP-13
Reactivity
Human
Applications
WB, ICC, IHC, EIA
Purity
Affinity Chromatography
Pricing
$165/0.1 mL | $205/0.2 mL | $345/0.5 mL | $425/1 mL | $1,220/5x1 mL
Activity Data
(Interleukin-6 (IL-6), a pro-inflammatory cytokine and an anti-inflammatory myokine, plays important roles in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. It has been reported that IL-6 significantly increased the MMP-10 protein lever in the human lung cancer A549 cells through the JAK/STAT signaling pathway. Briefly, A549 cells were seeded into 6-well cell culture clusters and allowed to grow to 50-70% confluence, then different concentrations of IL-6 was added. After incubated for 24h, the protein levels of MMP-10 in the cell supernatant were determined by Western blot.Result: MMP-10 protein lever significantly increased in A549 cells due to the stimulation of IL-6, the data was shown in Figure 1.)
Interleukin 6 (IL6), Active Protein (Cat# AAA2097342)
Full Name
Active Interleukin 6 (IL6)
Gene Names
Il6; ILg6; Ifnb2
Reactivity
Rat
Applications
Cell culture, Activity Assays
Purity
> 95%
Pricing
$215/0.01 mg | $450/0.05 mg | $690/0.1 mg | $850/0.2 mg | $1,660/0.5 mg | $2,470/1 mg | $6,035/5 mg
Western Blot (WB)
(Western blot analysis GFI1B using 293 whole cell lysates)
GFI1B, Polyclonal Antibody (Cat# AAA9602908)
Full Name
GFI1B Antibody
Gene Names
GFI1B; BDPLT17; ZNF163B
Reactivity
Human
Applications
WB, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Activity Data
(Figure. The binding activity of NOG with CDF5.Noggin, also known as NOG, is a protein that is involved in the development of many body tissues, including nerve tissue, muscles, and bones. Noggin is a signaling molecule that plays an important role in promoting somite patterning in the developing embryo. It is released from the notochord and regulates bone morphogenic protein (BMP4) during development. It also causes formation of the head and other dorsal structures. Besides, Growth Differentiation Factor 5 (GDF5) has been identified as an interactor of NOG, thus a binding ELISA assay was conducted to detect the interaction of recombinant human NOG and recombinant human CDF5. Briefly, NOG were diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to CDF5-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-NOG pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of NOG and CDF5 was shown in Figure 1, and this effect was in a dose dependent manner.)
Noggin (NOG), Active Protein (Cat# AAA2105168)
Full Name
Active Noggin (NOG)
Gene Names
NOG; SYM1; SYNS1; SYNS1A
Applications
Cell Culture, Activity Assays
Purity
> 95%
Pricing
$185/0.01 mg | $360/0.05 mg | $555/0.1 mg | $680/0.2 mg | $1,320/0.5 mg | $1,960/1 mg | $4,820/5 mg
Immunohistochemistry (IHC)
(Human kidney )
BMP7, Polyclonal Antibody (Cat# AAA3200866)
Full Name
BMP7 antibody - N-terminal region
Gene Names
BMP7; OP-1
Reactivity
Tested Reactivity: Human
Predicted Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
Predicted Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
Applications
IHC, WB
Purity
Protein A purified
Pricing
$390/0.1 mL | $1,750/5x0.1 mL
Western Blot (WB)
(Western blot analysis GDF11 using MCF7 whole cell lysates)
GDF11, Polyclonal Antibody (Cat# AAA9608741)
Full Name
GDF11 Antibody
Gene Names
GDF11; BMP11; BMP-11
Reactivity
Human
Applications
WB, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Western Blot (WB)
(Western blot analysis FLT3 using Jurkat whole cell lysates)
FLT3, Polyclonal Antibody (Cat# AAA9608863)
Full Name
FLT3 Antibody
Gene Names
FLT3; FLK2; STK1; CD135; FLK-2
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ICC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Soluble RANK Receptor, Active Protein (Cat# AAA146466)
Full Name
Recombinant Human Soluble RANK Receptor
Gene Names
TNFRSF11A; FEO; OFE; ODFR; OSTS; PDB2; RANK; CD265; OPTB7; TRANCER; LOH18CR1
Purity
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
$180/0.02 mg | $250/0.1 mg | $1,105/1 mg | $4,750/5x1 mg
Typical Testing Data/Standard Curve (for reference only)
GDF15, ELISA Kit (Cat# AAA2504512)
Full Name
Human GDF15 (Growth Differentiation Factor 15) ELISA Kit
Gene Names
GDF15; PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15
Reactivity
Human
Pricing
$440/48-Strip-Wells | $525/96-Strip-Wells | $2,215/5x96-Strip-Wells | $3,965/10x96-Strip-Wells | $250/24-Strip-Wells
Immunohistochemistry (IHC)
(Anti-GDF15 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
GDF15, Polyclonal Antibody (Cat# AAA248524)
Full Name
Rabbit Polyclonal to Human GDF15
Gene Names
GDF15; PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15
Reactivity
Human
Applications
IHC - Paraffin, WB, FC/FACS
Purity
Immunoaffinity Purified
Pricing
$610/0.2 mL | $2,685/5x0.2 mL
Immunohistochemistry (IHC)
(At 1/100 staining human kidney tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary)
CTGF, Polyclonal Antibody (Cat# AAA9610399)
Full Name
Phospho-CTGF (Ser118) Antibody
Gene Names
CCN2; CTGF; NOV2; HCS24; IGFBP8
Reactivity
Human, Mouse, Rat
Predicted: Pig, Bovine, Sheep, Rabbit, Chicken
Predicted: Pig, Bovine, Sheep, Rabbit, Chicken
Applications
WB, IHC, EIA
Purity
Purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Pricing
$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL
Western Blot (WB)
(Western Blot: Sample: Recombinant GDF5, Human.)
Growth Differentiation Factor 5, Polyclonal Antibody (Cat# AAA2026389)
Full Name
Polyclonal Antibody to Growth Differentiation Factor 5 (GDF5)
Gene Names
GDF5; OS5; LAP4; BDA1C; BMP14; CDMP1; LAP-4; SYM1B; SYNS2; BMP-14
Reactivity
Human
Applications
WB, ICC, IHC, EIA
Purity
Affinity Chromatography
Pricing
$160/0.1 mL | $205/0.2 mL | $335/0.5 mL | $410/1 mL | $1,200/5x1 mL
Immunohistochemistry (IHC)
(MBS9606895 at 1/100 staining Human Melanoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)
C19orf10, Polyclonal Antibody (Cat# AAA9606895)
Full Name
C19orf10 Antibody
Gene Names
MYDGF; IL25; IL27; SF20; IL27w; C19orf10; R33729_1; EUROIMAGE1875335
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Immunohistochemistry (IHC)
(MBS9601369 at 1/100 staining human brain tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)
BMP6, Polyclonal Antibody (Cat# AAA9601369)
Full Name
BMP6 Antibody
Gene Names
BMP6; VGR; VGR1
Reactivity
Human
Applications
WB, IHC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Immunohistochemistry (IHC)
(MBS9608490 at 1/100 staining Human kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)
GRN, Polyclonal Antibody (Cat# AAA9608490)
Full Name
GRN Antibody
Gene Names
GRN; GEP; GP88; PEPI; PGRN; CLN11; PCDGF
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Immunohistochemistry (IHC)
(Formalin-fixed, paraffin-embedded human GIST stained with CD117 Mouse Monoclonal Antibody (KIT/2674).)
CD117/c-Kit, Monoclonal Antibody (Cat# AAA4380609)
Full Name
CD117/c-Kit (Marker for Gastrointestinal Stromal Tumors)
Gene Names
KIT; PBT; SCFR; C-Kit; CD117; MASTC
Reactivity
Human. Others not known.
Applications
Formalin-Fixed
Purity
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Pricing
$390/0.1 mg (With BSA & Azide at 0.2mg/mL) | $390/0.1 mg (Without BSA & Azide at 1mg/mL) | $215/0.02 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (Without BSA & Azide at 1mg/mL)
Western Blot (WB)
(Western Blot: Sample: Mouse Sp2/0 Cells.)
Growth Differentiation Factor 10, Polyclonal Antibody (Cat# AAA2027436)
Full Name
Polyclonal Antibody to Growth Differentiation Factor 10 (GDF10)
Gene Names
Gdf10; Bmp3b
Reactivity
Mouse
Applications
WB, ICC, IHC, EIA
Purity
Affinity Chromatography
Pricing
$165/0.1 mL | $210/0.2 mL | $355/0.5 mL | $435/1 mL | $1,240/5x1 mL
Western Blot (WB)
(INHBA Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the INHBA antibody detected the INHBA protein (arrow).)
INHBA, Polyclonal Antibody (Cat# AAA9201920)
Full Name
INHBA Antibody (N-term)
Gene Names
INHBA; EDF; FRP
Reactivity
Human (Predicted Reactivity: Bovine, Mouse, Rat)
Applications
IF, EIA, WB, FC/FACS, IHC
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Pricing
$405/0.4 mL | $185/0.08 mL | $1,585/5x0.4 mL
Western Blot (WB)
(Western blot analysis of extracts from HT-29 cells, using GDF7 antibody.)
GDF7, Polyclonal Antibody (Cat# AAA9605552)
Full Name
GDF7 Antibody
Gene Names
GDF7; BMP12
Reactivity
Human
Applications
WB, IF, ICC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
SDS-Page
Connective Tissue Growth Factor (CTGF), Recombinant Protein (Cat# AAA7115194)
Full Name
Recombinant Human Connective Tissue Growth Factor (CTGF), Partial
Gene Names
CCN2; CTGF; NOV2; HCS24; IGFBP8
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
$1,415/1 mg (E-Coli) | $395/0.1 mg (E-Coli) | $245/0.02 mg (E-Coli) | $6,205/5x1 mg (E-Coli)
Western Blot (WB)
(The anti-hGDF2 N-term Pab is used in Western blot to detect hGDF2 in mouse liver tissue lysate.)
BMP9 (GDF2), Polyclonal Antibody (Cat# AAA9208359)
Full Name
BMP9 (GDF2) Antibody (N-term)
Gene Names
GDF2; BMP9; HHT5; BMP-9
Reactivity
Human, mouse
Applications
WB, EIA, IHC
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Pricing
$415/0.4 mL | $185/0.08 mL | $1,625/5x0.4 mL
Western Blot (WB)
(Figure 1: Western blot analysis using CDK5 mouse mAb against Hela (1), K562 (2), PC-12 (3) and Cos7 (4) cell lysate.)
CDK5, Monoclonal Antibody (Cat# AAA9602391)
Full Name
CDK5 Antibody
Gene Names
CDK5; LIS7; PSSALRE
Reactivity
Human, Rat, Monkey
Applications
WB, IHC, IF, ICC, EIA, FC/FACS
Purity
Affinity-Chromatography
Pricing
$260/0.05 mL | $325/0.1 mL | $400/0.2 mL | $1,750/5x0.2 mL
Activity Data
(Interleukin-6 (IL-6), a pro-inflammatory cytokine and an anti-inflammatory myokine, plays important roles in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. It has been reported that IL-6 significantly increased the MMP-10 protein lever in the human lung cancer A549 cells through the JAK/STAT signaling pathway. Briefly, A549 cells were seeded into 6-well cell culture clusters and allowed to grow to 50-70% confluence, then different concentrations of IL-6 was added. After incubated for 24h, the protein levels of MMP-10 in the cell supernatant were determined by Western blot.MMP-10 protein lever significantly increased in A549 cells due to the stimulation of IL-6, the data was shown in Figure 1.)
Interleukin 6 (IL6), Active Protein (Cat# AAA2097327)
Full Name
Active Interleukin 6 (IL6)
Gene Names
IL6; IL-6; CHIL-6; interleukin-6
Reactivity
Human
Applications
Cell culture, Activity Assays
Purity
> 95%
Pricing
$165/0.01 mg | $310/0.05 mg | $480/0.1 mg | $585/0.2 mg | $1,120/0.5 mg | $1,660/1 mg | $4,075/5 mg
Activity Data
(Figure. The binding activity of PAPPA with Plg.Pregnancy-associated plasma protein A (PAPPA), also known as pappalysin-1, is a secreted protease whose main substrate is insulin-like growth factor binding proteins. PAPPA's proteolytic function is activated upon collagen binding. It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses (fetuses with an abnormal number of chromosomes). Besides, Plasminogen (Plg) has been identified as an interactor of PAPPA, thus a binding ELISA assay was conducted to detect the interaction of recombinant human PAPPA and recombinant human Plg. Briefly, PAPPA were diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100muL were then transferred to Plg-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-PAPPA pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of PAPPA and Plg was shown in Figure 1, and this effect was in a dose dependent manner.)
Pregnancy Associated Plasma Protein A (PAPPA), Active Protein (Cat# AAA2105118)
Full Name
Active Pregnancy Associated Plasma Protein A (PAPPA)
Gene Names
PAPPA; PAPA; DIPLA1; PAPP-A; PAPPA1; ASBABP2; IGFBP-4ase
Applications
Cell Culture, Activity Assays
Purity
> 97%
Pricing
$215/0.01 mg | $445/0.05 mg | $685/0.1 mg | $845/0.2 mg | $1,645/0.5 mg | $2,450/1 mg | $5,990/5 mg
Activity Data
(PDGFA (Platelet-derived growth factor subunit A) is a Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. PDGFA has been described as a chemoattractant for monocytes and proven to be able to induce chemotactic migration of THP-1 cells. Therefore, chemotaxis assay used 24-well microchemotaxis system was undertaken to detect the chemotactic effect of PDGFA on the human monocytic cell line THP-1. Briefly, THP-1 cells were seeded into the upper chambers (100uL cell suspension,106cells/mL in RPMI 1640 with 0.5% FBS) and PDGFA (1.5ng/mL, 7.5ng/mL and 15ng/mL diluted separately in serum free RPMI 1640 ) was added in lower chamber with a polycarbonate filter (8um pore size) used to separate the two compartments. After incubation at 37oC with 5%CO2 for 3h, the filter was removed, then cells in low chamber were observed by inverted microscope at low magnification (×40) and the number of migrated cells were counted at high magnification (×400) randomly (five fields for each filter). Result shows PDGFA is able to induce migration of THP-1 cells. The migrated THP-1 cells in low chamber at low magnification (×40) were shown in Figure 1. Five fields of each chamber were randomly chosen, and the migrated cells were counted at high magnification (×400). Statistical results were shown in Figure 2. The optimum chemotaxis of PDGFA occurs at 1.5ng/mL.)
Platelet Derived Growth Factor Subunit A (PDGFA), Active Protein (Cat# AAA2097229)
Full Name
Active Platelet Derived Growth Factor Subunit A (PDGFA)
Reactivity
Mouse
Applications
Cell culture, Activity Assays
Purity
> 95%
Pricing
$230/0.01 mg | $495/0.05 mg | $765/0.1 mg | $945/0.2 mg | $1,845/0.5 mg | $2,730/1 mg | $6,670/5 mg
Immunofluorescence (IF)
(MBS9601751 staining NIH-3T3 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37 degree C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.)
Met, Polyclonal Antibody (Cat# AAA9601751)
Full Name
Met Antibody
Gene Names
MET; HGFR; AUTS9; RCCP2; c-Met; DFNB97
Reactivity
Human, Mouse
Applications
WB, IF, ICC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Western Blot (WB)
(Western blot analysis of BMP3B using LOVO whole cell lysates)
BMP3B, Polyclonal Antibody (Cat# AAA9609599)
Full Name
BMP3B Antibody
Gene Names
GDF10; BIP; BMP3B; BMP-3b
Reactivity
Human
Applications
WB, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
GDF2, Active Protein (Cat# AAA553714)
Full Name
GDF2
Gene Names
GDF2; BMP9; HHT5; BMP-9
Applications
SDS-PAGE
Purity
>95%, as determined by SDS-PAGE and HPLC.
Pricing
$290/0.01 mg | $210/0.02 mg | $5,835/1 mg
Western Blot (WB)
(Western blot analysis of extracts of HeLa, using CTGF antibody. The lane on the left is treated with the antigen-specific peptide.)
CTGF, Polyclonal Antibody (Cat# AAA9607743)
Full Name
CTGF Antibody
Gene Names
CCN2; CTGF; NOV2; HCS24; IGFBP8
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Immunofluorescence (IF)
(MBS9601935 staining COS7 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37 degree C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.)
CDK5, Polyclonal Antibody (Cat# AAA9601935)
Full Name
CDK5 Antibody
Gene Names
CDK5; LIS7; PSSALRE
Reactivity
Human, Mouse, Rat, Monkey
Applications
WB, IHC, IF, ICC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
