Flow Cytometry (FC/FACS)
(Staining of mouse platelets with CD61 antibody (FITC) and 0.06 ug of Rat IgG1 K Isotype Control (biotin) (left) or 0.06 ug of CD41 antibody (biotin) (right) followed by Streptavidin (PE).)
Rat CD41 Monoclonal Antibody | anti-CD41 antibody
CD41 antibody (biotin)
Applications
Flow Cytometry, Functional Assay
Synonyms
CD41; Monoclonal Antibody; CD41 antibody (biotin); Monoclonal CD41; Anti-CD41; CD-41; ITGA2b; fibrinogen receptor; gpIIb/IIIa; CD 41; anti-CD41 antibody
Host
Rat
Clonality
Monoclonal
Isotype
IgG1 kappa
Clone Number
MWReg30
Specificity
Mouse
Form/Format
Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer.
Concentration
500 ug/ml (varies by lot)
Sequence Length
185
Applicable Applications for anti-CD41 antibody
Flow Cytometry (FC/FACS)
Application Notes
FC: <=.015 ug/test
A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Biological Significance
The MWReg30 monoclonal antibody reacts with mouse CD41. While initially thought to be expressed exclusively on the surface of platelets and megakaryocytes, it has been demonstrated that CD41 is also expressed on hematopoietic progenitors in the embryo, fetus and adult. CD41 associates with CD61 to form a receptor which plays a major role in platelet function, including binding of several adhesion molecules such as fibrinogen, fibronectin and vitronectin.Recently, the SLAM-family markers, CD48 and CD150 have been used to reliably identify hematopoietic stem cells. Specifically, it was found that CD150+CD48- bone marrow cells were highly efficient in their ability to confer long-term multi-lineage reconstitution in irradiated mice. Furthermore, the efficiency of reconstitution was enhanced when HSCs were further enriched through the exclusion of CD41+ cells. Thus, the use of CD150+CD48-CD41- as an expression profile efficiently identifies hematopoietic stem cells.
Tag/Conjugate
Biotin
Preparation and Storage
Store at 2-8 degree C. Do not freeze. Protect from light.
Flow Cytometry (FC/FACS)
(Staining of mouse platelets with CD61 antibody (FITC) and 0.06 ug of Rat IgG1 K Isotype Control (biotin) (left) or 0.06 ug of CD41 antibody (biotin) (right) followed by Streptavidin (PE).)
Flow Cytometry (FC/FACS)
(Staining of mouse platelets with CD61 antibody (FITC) and 0.06 ug of Rat IgG1 K Isotype Control (biotin) (left) or 0.06 ug of CD41 antibody (biotin) (right) followed by Streptavidin (PE).)
Related Product Information for anti-CD41 antibody
Rat monoclonal CD41 antibody (biotin)
Product Categories/Family for anti-CD41 antibody
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
20,050 Da
NCBI Official Full Name
CD41 antigen, partial
UniProt Protein Name
CD41 antigen
UniProt Gene Name
CD41
UniProt Entry Name
F7J059_TURTR
Similar Products
Product Notes
The CD41 cd41 (Catalog #AAA832383) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD41 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). FC: <=.015 ug/test A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Researchers should empirically determine the suitability of the CD41 cd41 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD41, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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