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60 results for "caspase-activity-and-apoptosis-inhibitor" - showing 1-50
Structure
Z-VAD-FMK, Inhibitor (Cat# AAA578589)
Full Name
Z-VAD-FMK
Purity
99.41%
Pricing
$200/1 mg | $230/2 mg | $265/5 mg | $315/10 mg | $465/25 mg | $265/1 mL (in DMSO) | $1,815/5x25 mg
Testing Data
(Staining of human peripheral blood lymphocytes with Mouse anti Human CD299: Azide Free (MBS210211))
CD229, Monoclonal Antibody (Cat# AAA212512)
Full Name
MOUSE ANTI HUMAN CD229
Gene Names
LY9; hly9; mLY9; CD229; SLAMF3
Applications
FC/FACS, IP
Pricing
$525/0.2 mg | $2,210/5x0.2 mg
Western Blot (WB)
(Western blot analysis of lysates from A549 cell line and human plasma tissue lysate(from left to right), using CLU Antibody (N-term). MBS9215265 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
CLU, Polyclonal Antibody (Cat# AAA9215265)
Full Name
CLU Antibody (N-term)
Gene Names
CLU; CLI; AAG4; APOJ; CLU1; CLU2; KUB1; SGP2; APO-J; SGP-2; SP-40; TRPM2; TRPM-2; NA1/NA2
Reactivity
Human, mouse, rat
Applications
FC, WB, IHC-P, EIA
Purity
This antibody is purified through a protein A column, followed by peptide affinity purification.
Pricing
$415/0.4 mL | $185/0.08 mL | $1,625/5x0.4 mL
Western Blot (WB)
(Western blot analysis of APP (arrow) using rabbit polyclonal APP Antibody (N-term) (RB05012). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the APP gene (Lane 2) (Origene Technologies).)
APP, Polyclonal Antibody (Cat# AAA9212747)
Full Name
APP Antibody (N-term)
Gene Names
APP; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma
Reactivity
Mouse (Predicted Reactivity: Monkey)
Applications
WB, EIA, IHC-p, FC
Purity
This antibody is purified through a protein A column, followed by peptide affinity purification.
Pricing
$405/0.4 mL | $185/0.08 mL | $1,585/5x0.4 mL
Testing Data
(Normal (left) and keratoconus (right) corneal fibroblasts were treated with 200uM H2O2 for 1hr, washed, and allowed to recover for 1-3hrs. The culture media was removed and replaced with 1x FAM-FLICA Caspases 3&7 solution (in culture media) at 300ul/well for 1hr. The cell layer was washed 3 times with 1x wash buffer; 300ul wash buffer was added to keep the cells from drying. Keratoconus corneal fibroblasts treated with H2O2 (right) show a significant increase in caspases 3&7 activity compared to normal cells (left). Non-apoptotic cells are dark in background. Data courtesy of Dr. Cristina Kenney, M.D., Ph.D. Dept. of Ophthalmology, UC Irvine.)
FAM-FLICA Caspase 3 & 7, Assay Kit (Cat# AAA258028)
Full Name
FAM-FLICA Caspase 3 & 7 Assay Kit
Pricing
$665/100 Tests | $300/25 Tests | $3,010/5x100 Tests
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
c ABL (ABL1), Polyclonal Antibody (Cat# AAA9213319)
Full Name
c ABL (ABL1) Antibody (C-term)
Gene Names
ABL1; ABL; JTK7; p150; c-ABL; v-abl; c-ABL1; bcr/abl
Reactivity
Human
Applications
EIA, IHC-P, WB
Purity
This antibody is purified through a protein A column, followed by peptide affinity purification.
Pricing
$405/0.4 mL | $185/0.08 mL | $1,585/5x0.4 mL
TL1A, Polyclonal Antibody (Cat# AAA535934)
Full Name
TL1A antibody
Gene Names
TNFSF15; TL1; TL1A; VEGI; VEGI192A
Reactivity
Human TL1A
Applications
EIA, WB
Pricing
$425/0.05 mg | $1,905/5x0.05 mg
Aven, Blocking Peptide (Cat# AAA152194)
Full Name
Aven Peptide
Gene Names
AVEN; PDCD12
Applications
BL
Pricing
$170/0.05 mg | $765/5x0.05 mg
Testing Data
(Jurkat cells were treatedwith staurosporine, anapoptosis-inducingagent (bottom), orDMSO, a negativecontrol (top), for 4hours, then incubatedwith ICT's green caspase6 inhibitor probe,FAM-VEID-FMK, for 1hour. Cells were washedtwice and read on a flowcytometer. Treatment with staurosporine induced caspase 6 activity in 95.2% ofthe experimental cells (P3, bottom right), whereas the negative controltreatment exhibited caspase 6 activity in only 5.9% of the cell population (P3,top right). This is a ratio of 16:1. (Dr. Brian W. Lee, ICT).)
FAM-FLICA Caspase 6, Assay Kit (Cat# AAA258019)
Full Name
FAM-FLICA Caspase 6 Assay Kit
Pricing
$665/100 Tests | $300/25 Tests | $3,010/5x100 Tests
Western Blot (WB)
(Western blot analysis of Aven in Raji cell lysate with Aven antibody at 1 μg/mL in (A) the presence and (B) the absence of blocking peptide (2413P).)
Aven, Blocking Peptide (Cat# AAA153094)
Full Name
Aven Peptide
Gene Names
AVEN; PDCD12
Applications
BL
Pricing
$170/0.05 mg | $765/5x0.05 mg
Testing Data
(FLUORESCENCE PROPERTIES OF FLICA 660POLY CASPASE REAGENT:Excitation max:660 nm Emission max: 690nm)
FLICA 660 Poly Caspase, Assay Kit (Cat# AAA258017)
Full Name
FLICA 660 Poly Caspase Assay Kit
Pricing
$335/25-50 Tests
SMAC/DIABLO, Monoclonal Antibody (Cat# AAA670144)
Full Name
Mouse Anti-Human SMAC/DIABLO-UNLB
Gene Names
DIABLO; SMAC; SMAC3; DIABLO-S; FLJ10537; FLJ25049
Reactivity
Human
Applications
ELISA; Western Blot
Pricing
$400/0.1 mg | $1,645/5x0.1 mg
FLIP, Blocking Peptide (Cat# AAA151900)
Full Name
FLIP Peptide
Gene Names
CFLAR; CASH; FLIP; MRIT; CLARP; FLAME; Casper; FLAME1; c-FLIP; FLAME-1; I-FLICE; c-FLIPL; c-FLIPR; c-FLIPS; CASP8AP1
Applications
BL
Pricing
$170/0.05 mg | $765/5x0.05 mg
RFI, Polyclonal Antibody (Cat# AAA222824)
Full Name
RABBIT ANTI HUMAN RFI
Gene Names
RNF34; RFI; RIF; RIFF; hRFI; CARP1; CARP-1
Reactivity
Bovine (Expected from Sequence), Dog (Expected from Sequence), Mouse (Expected from Sequence), New World primate (Expected from Sequence), Rat (Expected from Sequence)
Applications
EIA, WB
Pricing
$420/0.1 mg | $1,735/5x0.1 mg
Western Blot (WB)
(Mouse Cdkn2a Antibody (Center) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the Cdkn2a antibody detected the Cdkn2a protein (arrow).)
Cdkn2a, Polyclonal Antibody (Cat# AAA9204567)
Full Name
Mouse Cdkn2a Antibody (Center)
Gene Names
Cdkn2a; Arf; p16; MTS1; Pctr1; p19ARF; p16INK4a; p19<ARF>; ARF-INK4a; INK4a-ARF; Ink4a/Arf; p16(INK4a)
Reactivity
Mouse
Applications
WB, EIA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Pricing
$405/0.4 mL | $185/0.08 mL | $1,585/5x0.4 mL
chromosome 9 open reading frame 82, ELISA Kit (Cat# AAA9316497)
Full Name
Human Uncharacterized protein C9orf82, C9orf82 ELISA Kit
Gene Names
CAAP1; CAAP; C9orf82
Reactivity
Human
Pricing
$540/48-Strip-Wells | $755/96-Strip-Wells | $3,410/5x96-Strip-Wells | $6,715/10x96-Strip-Wells
Caspase 1, Inhibitor (Cat# AAA655446)
Full Name
Caspase 1 (ICE-Family) Inhibitor, Cell Culture, 2mM, (YVAD-FMK)
Gene Names
Casp1; Ice; Il1bc
Purity
Highly Purified
98% (HPLC)
98% (HPLC)
Pricing
$425/0.1 mL | $1,900/5x0.1 mL
Testing Data
(Jurkat cells were treated withstaurosporine, an apoptosis-inducingagent (bottom), or DMSO, a negativecontrol (top), for 4 hours, thenincubated with ICT's green caspase 10inhibitor probe, FAM-AEVD-FMK, for 1hour. Cells were washed twice and readon a flow cytometer. Treatment withstaurosporine induced caspase 10activity in 93.6% of the experimentalcells (M2, bottom right), whereas thenegative control treatment exhibitedcaspase 10 activity in only 4.7% of thecell population (M2, top right). This is a ratio of 20:1. (Dr. Brian W. Lee, ICT).)
FAM-FLICA Caspase 10, Assay Kit (Cat# AAA258025)
Full Name
FAM-FLICA Caspase 10 Assay Kit
Pricing
$665/100 Tests | $300/25 Tests | $3,010/5x100 Tests
Western Blot (WB)
(Western blot analysis of APP-pY756 in T47D cell line lysates (35ug/lane). APP (arrow) was detected using the purified Pab.)
APP-Y756, Polyclonal Antibody (Cat# AAA9209531)
Full Name
APP-Y756 Antibody
Gene Names
APP; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma
Reactivity
Human (Predicted Reactivity: Monkey, Mouse, Pig, Rat)
Applications
WB, EIA
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Pricing
$405/0.4 mL | $185/0.08 mL | $1,585/5x0.4 mL
Testing Data
(Jurkat cells were treated with 1uM staurosporine to induce caspaseactivity (top), or a negative control (bottom) for 3 hours, incubatedwith ICT's red poly caspases inhibitor probe, SR-VAD-FMK, for 1 hour,washed twice, and examined under a fluorescence microscope (DICimages were also taken). The color image of induced cells (upper left)reveals experimental cells which fluoresce red, therefore they all havesome degree of caspase activity. The non-induced DIC image (lowerright) reveals many control cells, however the correspondingfluorescence image (lower left) is dark; none of these cells have activecaspases (Dr. Brian W. Lee, ICT).)
SR-FLICA Poly Caspase, Assay Kit (Cat# AAA258012)
Full Name
SR-FLICA Poly Caspase Assay Kit
Pricing
$665/100 Tests | $300/25 Tests | $3,010/5x100 Tests
Testing Data
(Jurkat cells were treatedwith staurosporine, anapoptosis-inducing agent(bottom), or DMSO,a negative control (top), for4 hours, then incubatedwith ICT's green caspase 2 inhibitor probe, FAM-VDVAD-FMK, for 1 hour. Cells were washed twice and read on a flow cytometer. Treatment with staurosporine induced caspase2 activity in 63.2% of the experimental cells (M2, bottom right), whereas thenegative control treatment exhibited caspase 2 activity in only 7.2% of the cellpopulation (M2, top right). This is a ratio of 9:1. (Dr. Brian W. Lee, ICT).)
FAM-FLICA Caspase 2, Assay Kit (Cat# AAA258004)
Full Name
FAM-FLICA Caspase 2 Assay Kit
Pricing
$665/100 Tests | $300/25 Tests | $3,010/5x100 Tests
FLIP, Blocking Peptide (Cat# AAA153114)
Full Name
FLIP Peptide
Gene Names
CFLAR; CASH; FLIP; MRIT; CLARP; FLAME; Casper; FLAME1; c-FLIP; FLAME-1; I-FLICE; c-FLIPL; c-FLIPR; c-FLIPS; CASP8AP1
Applications
BL
Pricing
$170/0.05 mg | $765/5x0.05 mg
FLIP, Blocking Peptide (Cat# AAA152309)
Full Name
FLIP Peptide
Gene Names
CFLAR; CASH; FLIP; MRIT; CLARP; FLAME; Casper; FLAME1; c-FLIP; FLAME-1; I-FLICE; c-FLIPL; c-FLIPR; c-FLIPS; CASP8AP1
Applications
BL
Pricing
$170/0.05 mg | $765/5x0.05 mg
FLIP, Blocking Peptide (Cat# AAA152489)
Full Name
FLIP Peptide
Gene Names
CFLAR; CASH; FLIP; MRIT; CLARP; FLAME; Casper; FLAME1; c-FLIP; FLAME-1; I-FLICE; c-FLIPL; c-FLIPR; c-FLIPS; CASP8AP1
Applications
BL
Pricing
$170/0.05 mg | $765/5x0.05 mg
Western Blot (WB)
(Western Blot: Cell extracts from Jurkat cells treated with 0.25mg/ml cytochrome c, using Caspase 3, Cleaved (Asp175) Pab Rb xHu|C2087-16A without preincubation (left) and preincubated with Caspase 3, Cleaved (Asp175)|C2087-16A1 as Blocking Peptide (right).)
Caspase 3, Cleaved, Inhibitor (Cat# AAA655367)
Full Name
Caspase 3, Cleaved (Asp175) (CPP-32, Apoptain, Yama, SCA-1) Blocking Peptide
Gene Names
CASP3; CPP32; SCA-1; CPP32B
Applications
EL/EIA
Purity
Purified
Purified
Purified
Pricing
$375/0.1 mg | $1,670/5x0.1 mg
Testing Data
(Mouse EL4 thymoma cellswere cultured in the absence(A) or presence (B) of 100 ugmitomycin for 18 hours. Thecells were harvested andstained with ICT'sSR-DEVD-FMK inhibitor probe(red histograms) to detect active caspases 3&7. The data illustrate a low level ofcaspase-3 activity in untreated cells (A) compared to unstained control (bluehistogram); caspase-3 activity is greatly enhanced in the mitomycin treatedcultures (B). Cells were analyzed with a BD LSRII flow cytometer to detectsulforhodamine using the green laser (532nm) and detector D set up with filter610/620 600LP (Dr. Catherine Martone, Yale University).)
SR FLICA Caspase 3 and 7, Assay Kit (Cat# AAA258021)
Full Name
SR FLICA Caspase 3 and 7 Assay Kit
Pricing
$665/100 Tests | $300/25 Tests | $3,010/5x100 Tests
Testing Data
(Jurkat cells were treated with 1 uM staurosporine toinduce caspase 9 activity (left), or a negative control(right) for 3 hours, washed twice, then incubated withICT's red caspase 9 inhibitor probe, SR-LEHD-FMK, for 1hour and examined under a fluorescence microscope.DIC images were also taken of all cells. Both inducedimages reveal several experimental cells which fluorescered, therefore they have some degree of caspase 9activity. The non-induced DIC image reveals many controlcells, however the corresponding fluorescence image isdark; none of these cells have active caspase 9 (Dr. BrianW. Lee, ICT).)
SR-FLICA Caspase 9, Assay Kit (Cat# AAA258030)
Full Name
SR-FLICA Caspase 9 Assay Kit
Pricing
$665/100 Tests | $300/25 Tests | $3,010/5x100 Tests
Testing Data
(Jurkat cells lymphocytes) weretreated with 1 muM staurosporinefor 4 hours to induce apoptosis viacaspase activity. Cells were thenstained with either FAM-VAD-OPHI or FLICA FAM-VAD-FMKgreen fluorescent polycaspase inhibitor probes at 10 muM for 1 hour. Cells were washed twiceand read on a BD FACSCantoflowcytometer. Histograms weremade of cell fluorescence intensity output. Staining results with the OPH-based caspase inhibitor (grey solid) are consistent with those achieved using the FMK-based caspase inhibitor (greenoutline). FAM-VAD-OPH caspase inhibitor reagents mirror FAM-VAD-FMKanalogs for in vitro apoptosis detection, and they may be less toxic and more stable.)
FAM-DEVD-OPH in vitro Apoptosis, Detection Reagent (Cat# AAA258040)
Full Name
FAM-DEVD-OPH in vitro Apoptosis Detection Reagent, Pack of 4 Vials
Pricing
$610/4 Vials | $2,685/5x4 Vials
Conserved anti-apoptotic protein (CAAP), Recombinant Protein (Cat# AAA1380374)
Full Name
Recombinant Human Conserved anti-apoptotic protein (CAAP)
Gene Names
CAAP1; CAAP; C9orf82
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
$1,915/1 mg (E-Coli) | $2,305/1 mg (Yeast) | $3,455/1 mg (Baculovirus) | $1,765/0.1 mg (Baculovirus) | $2,355/0.1 mg (Mammalian-Cell) | $1,070/0.1 mg (E-Coli) | $1,160/0.1 mg (Yeast) | $6,040/0.5 mg (Mammalian-Cell) | $1,225/0.02 mg (Baculovirus) | $1,490/0.02 mg (Mammalian-Cell) | $890/0.02 mg (E-Coli) | $1,015/0.02 mg (Yeast)
Conserved anti-apoptotic protein (CAAP), Recombinant Protein (Cat# AAA1403979)
Full Name
Recombinant Bovine Conserved anti-apoptotic protein (CAAP)
Gene Names
CAAP1; CAAP; C9orf82; C8H9orf82
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
$1,920/1 mg (E-Coli) | $2,310/1 mg (Yeast) | $3,455/1 mg (Baculovirus) | $1,765/0.1 mg (Baculovirus) | $2,355/0.1 mg (Mammalian-Cell) | $1,070/0.1 mg (E-Coli) | $1,160/0.1 mg (Yeast) | $6,040/0.5 mg (Mammalian-Cell) | $1,225/0.02 mg (Baculovirus) | $1,490/0.02 mg (Mammalian-Cell) | $890/0.02 mg (E-Coli) | $1,020/0.02 mg (Yeast)
Testing Data
(Jurkat cells were treated with 1 uM staurosporine for 3 hours to induce caspase 9 activity (top), or were treated with a control (bottom). Both populations were incubated with ICT's green FAM-LEHD-FMK FLICA caspase 9 reagent. DIC images were taken of both samples. Almost all cells in the induced sample (top) fluoresce green therefore they have activated caspase 9. None of the control cells (bottom) fluoresce green, therefore they do not have activated caspase 9 (Dr. Brian Lee, ICT).)
FAM-FLICA Caspase 9, Assay Kit (Cat# AAA258024)
Full Name
FAM-FLICA Caspase 9 Assay Kit
Pricing
$665/100 Tests | $300/25 Tests | $3,010/5x100 Tests
AZD5153, Inhibitor (Cat# AAA579634)
Full Name
AZD5153
Purity
98.2%
Pricing
$215/2 mg | $255/5 mg | $335/10 mg | $545/25 mg | $890/50 mg | $1,335/100 mg | $335/1 mL (in DMSO) | $5,745/5x100 mg
Caspase, Inhibitor (Cat# AAA655455)
Full Name
Caspase (ICE-Family) Inhibitor, Cell Culture, 2mM, (Z-VAD-FMK)
Purity
Highly Purified
One spot by TLC analysis.
One spot by TLC analysis.
Pricing
$425/0.1 mL | $1,900/5x0.1 mL
Conserved anti-apoptotic protein (Caap), Recombinant Protein (Cat# AAA1467733)
Full Name
Recombinant Mouse Conserved anti-apoptotic protein (Caap)
Gene Names
Caap1; CAAP; AI536248; 5830433M19Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
$1,905/1 mg (E-Coli) | $2,295/1 mg (Yeast) | $3,440/1 mg (Baculovirus) | $1,755/0.1 mg (Baculovirus) | $2,345/0.1 mg (Mammalian-Cell) | $1,060/0.1 mg (E-Coli) | $1,150/0.1 mg (Yeast) | $6,030/0.5 mg (Mammalian-Cell) | $1,220/0.02 mg (Baculovirus) | $1,485/0.02 mg (Mammalian-Cell) | $880/0.02 mg (E-Coli) | $1,010/0.02 mg (Yeast)
Testing Data
(Jurkat cells were grown in suspension to 4 x 10^5 cells/mL, then divided into two separate TC-flasks. One population, "Non-Induced", received a DMSO vehicle control (A). The other population, "Induced", was spiked with 1 muM staurosporine (B). Cells were incubated for 4 hours at 37 degree C, then stained with red SR-FLICA caspase-8 inhibitor, SR-LETD-FMK (kit catalog #9150) for 1 hour at 37 degree C. After labeling, samples were washed three times and slides were prepared. Fluorescence images were acquired using a Nikon Eclipse 90i microscope equipped with a Hamamatsu Flash 4.0 camera. In the treated sample, cells appear bright red, indicating a high level of caspase-8 activity (B, Induced, right). In the non-induced sample, few red positive cells are visible, indicating minimal caspase-8 activity (A, Non-Induced, left). Data courtesy of Mrs. Tracy Murphy (220:68, 121815).)
SR FLICA Caspase 8, Assay Kit (Cat# AAA258048)
Full Name
SR FLICA Caspase 8 Assay Kit
Pricing
$665/100 Tests | $300/25 Tests | $3,010/5x100 Tests
CAAP1, siRNA (Cat# AAA8237675)
Full Name
CAAP1 siRNA (Mouse)
Gene Names
Caap1; CAAP; AI536248; 5830433M19Rik
Reactivity
Mouse
Applications
RNAi
Purity
> 97%
Pricing
$395/15 nmol | $555/30 nmol | $2,440/5x30 nmol
CAAP1, siRNA (Cat# AAA8230115)
Full Name
CAAP1 siRNA (Human)
Gene Names
CAAP1; CAAP; C9orf82
Reactivity
Human
Applications
RNAi
Purity
> 97%
Pricing
$395/15 nmol | $555/30 nmol | $2,440/5x30 nmol
POLYPHYLLIN D, Inhibitor (Cat# AAA579836)
Full Name
POLYPHYLLIN D
Purity
99.0%
Pricing
$200/5 mg | $230/10 mg | $770/5x10 mg
Senegenin, Inhibitor (Cat# AAA579844)
Full Name
Senegenin
Purity
98.9%
Pricing
$170/1 mg | $200/5 mg | $230/10 mg | $230/1 mL (in DMSO) | $770/5x10 mg
Polyphyllin B, Inhibitor (Cat# AAA579647)
Full Name
Polyphyllin B
Purity
100.0%
Pricing
$325/5 mg | $445/10 mg | $1,730/5x10 mg
Western Blot (WB)
(Host: RabbitTarget Name: C9ORF82Sample Tissue: Human DLD1 Whole Cell lysatesAntibody Dilution: 1ug/ml)
CAAP1, Polyclonal Antibody (Cat# AAA3221078)
Full Name
CAAP1 Antibody - middle region
Gene Names
CAAP1; CAAP; C9orf82
Reactivity
Human
Applications
WB
Purity
Affinity purified
Pricing
$445/0.1 mL | $1,985/5x0.1 mL
Ginsenoside Rh2, Inhibitor (Cat# AAA579789)
Full Name
Ginsenoside Rh2
Purity
98.0%
Pricing
$200/1 mg | $290/5 mg | $360/10 mg | $585/25 mg | $2,365/5x25 mg
HTRA2 / Serine Protease HTRA2, Recombinant Protein (Cat# AAA2902749)
Full Name
Human HTRA2 / Serine Protease HTRA2, Mitochondrial Recombinant Protein
Gene Names
HTRA2; OMI; MGCA8; PARK13; PRSS25
Applications
EIA, WB, AP
Purity
>95% by SDS-PAGE
beta Amyloid 1-42, Polyclonal Antibody (Cat# AAA9629019)
Full Name
beta Amyloid 1-42 Antibody
Gene Names
APP; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma
Reactivity
Human
Applications
EIA, peptide
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
CAAP1, Polyclonal Antibody (Cat# AAA8564031)
Full Name
CAAP1
Reactivity
Human
Predicted: Rat, Mouse
Predicted: Rat, Mouse
Applications
EIA, WB, IHC
Purity
Purified By Antigen Affinity Column
Pricing
$350/0.2 mL | $570/0.1 mL (Biotin) | $1,515/5x0.2 mL | $570/0.1 mL (FITC) | $570/0.1 mL (AF350) | $570/0.1 mL (AF405) | $570/0.1 mL (AF488) | $570/0.1 mL (AF555) | $570/0.1 mL (AF568)
 were able to identify hepatocytes in which caspases were activated. Segmental normothermic ischemia of the liver was induced for 120 minutes. Six hours post-reperfusion, FAM-FLIVO was injected into the portal veins of the rats and left to circulate for 10 minutes. Images were taken from 5 um cryosections of liver with the nuclei visualized in blue using DAPI (400X). A bright green signal is clearly seen in hepatocytes containing active caspases distributed around the vessel in the ischemic condition (right) compared to the control non-ischemic tissue (left).MBS258407_TD2.jpg){kind=spacer}
Testing Data
(CASPASE ACTIVITY IN RAT BRAIN. Using FAM-FLIVO to monitor cell death, there is a clear distinction between healthy and apoptotic neurons. In this live animal brain study of diabetes, Dr. Thomas Morrow at the University of Michigan VAMC Ann Arbor was able to assess neurodegeneration via caspase activity in control (left) and 8-week STZ diabetic rats (right). 30 minutes prior to sacrifice, FAM-FLIVO was injected intravenously to directly label caspase-positive apoptotic neurons. After sacrifice, 20 µm frozen sections of the periaqueductal gray (PAG) were prepared and counter-stained with red fluorescent Nissl to identify all neurons. Dying apoptotic neurons exhibit dual staining with FAM-FLIVO (yellow/green) and Nissl (red). In this model, diabetic animals show greater levels of caspase activity in the PAG than control animals.)
FAM-FLIVO Poly Caspase, Assay Kit (Cat# AAA258407)
Full Name
FAM-FLIVO In vivo Poly Caspase Assay
Pricing
$610/24 Tests | $2,740/5x24 Tests | $290/6 Tests
CFLAR / CASP8 And FADD-Like Apoptosis Regulator, Recombinant Protein (Cat# AAA2902708)
Full Name
Human CFLAR / CASP8 And FADD-Like Apoptosis Regulator Recombinant Protein
Gene Names
CFLAR; CASH; FLIP; MRIT; CLARP; FLAME; cFLIP; Casper; FLAME1; c-FLIP; FLAME-1; I-FLICE; c-FLIPL; c-FLIPR; c-FLIPS; CASP8AP1
Applications
EIA, WB, AP
Purity
>95% by SDS-PAGE
CAAP1, Blocking Peptide (Cat# AAA3245867)
Full Name
CAAP1 Peptide - middle region
Gene Names
CAAP1; CAAP; C9orf82
Reactivity
Human
Applications
WB
Pricing
$170/0.1 mg | $720/5x0.1 mg
Neocurdione, Inhibitor (Cat# AAA5760699)
Full Name
Neocurdione
Purity
98.00%
Pricing
$360/1 mg | $800/5 mg | $3,310/5x5 mg
Lupiwighteone, Inhibitor (Cat# AAA5760610)
Full Name
Lupiwighteone
Purity
98.00%
Pricing
$550/5 mg | $2,170/5x5 mg
