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Type
Reactivity
Gene Name
Isotype
Host
Application
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47 results for "MEK1 2 inhibitor" - showing 1-47
Western Blot (WB)
(Western Blot analysis of purified MAPK phospho-proteins or extracts from NIH/3T3 cells treated with UV light and PDGF, using MBS600367 (upper), M2352-05E (middle), and MBS600367.)
MAP Kinase p44/42, Monoclonal Antibody (Cat# AAA600367)
Full Name
MAP Kinase p44/42, phosphorylated (Thr202/Tyr204) (MAPK3/MAPK1, Mitogen-activated Protein Kinase 1, MAP Kinase 1, MAPK 1, ERT1, Extracellular Signal-regulated Kinase 2, ERK-2, MAP Kinase Isoform p42, p42-MAPK, Mitogen-activated Protein Kinase 2, MAP Kinas
Reactivity
Drosophila, Human, Monkey, Mouse, Porcine, Rat0
Applications
WB, FC/FACS, IF
Purity
Supernatant
Supernatant
Supernatant
Pricing
$650/0.2 mL | $2,905/5x0.2 mL
Western Blot (WB)
(Western blot analysis of extracts from various cells, using MBS608615)
MAP Kinase p44/42, Monoclonal Antibody (Cat# AAA608615)
Full Name
MAP Kinase p44/42 (MAPK3/MAPK1, Mitogen-activated Protein Kinase 1, MAP Kinase 1, MAPK 1, ERT1, Extracellular Signal-regulated Kinase 2, ERK-2, MAP Kinase Isoform p42, p42-MAPK, Mitogen-activated Protein Kinase 2, MAP Kinase 2, MAPK 2, ERK2, PRKM1, PRKM2
Reactivity
Hamster, Human, Monkey, Mouse, Porcine, Rat
Applications
EL/EIA, WB, IHC
Purity
Purified
Purified
Purified
Pricing
$610/0.1 mL | $2,730/5x0.1 mL
Testing Data
(Specificity and sensitivity of MBS615382. The antibody reacts specifically with as little as 0.25ng of phosphorylated p42 MAP kinase and does not cross-react with up to 4ug of nonphosphorylated p42 MAP kinase.)
MAP Kinase p44, p42, Polyclonal Antibody (Cat# AAA615382)
Full Name
MAP Kinase p44, p42, phosphorylated (Thr202, Tyr204) (MAPK3/MAPK1, Mitogen-activated Protein Kinase 1, MAP Kinase 1, MAPK 1, ERT1, Extracellular Signal-regulated Kinase 2, ERK-2, MAP Kinase Isoform p42, p42-MAPK, Mitogen-activated Protein Kinase 2, MAP Ki
Gene Names
MAPK3; ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK
Reactivity
Bovine, Chicken, Hamster, Human, Monkey, Mouse, Rat
Applications
EL/EIA, WB, IP, ICC, FC/FACS, IF
Purity
Affinity Purified
Purified by Protein A and peptide affinity chromatography.
Purified by Protein A and peptide affinity chromatography.
Pricing
$645/0.2 mL | $2,885/5x0.2 mL
Structure
Baricitinib, Inhibitor (Cat# AAA576687)
Full Name
Baricitinib (LY3009104, INCB028050)
Purity
98.9%
Pricing
$185/2 mg | $195/5 mg | $205/10 mg | $230/25 mg | $245/50 mg | $270/100 mg | $195/1 mL (in DMSO) | $950/5x100 mg
U0126, Inhibitor (Cat# AAA515067)
Full Name
U0126
Purity
>98% (TLC); NMR (Conforms)
Pricing
$190/10 mg | $320/50 mg | $1,225/5x50 mg
Structure
Trametinib, Inhibitor (Cat# AAA576333)
Full Name
Trametinib (GSK1120212)
Purity
99.88%
Pricing
$185/5 mg | $195/10 mg | $210/50 mg | $240/100 mg | $275/200 mg | $195/1 mL (in DMSO) | $970/5x200 mg
Structure
(Structure of P3120-58.)
PD-325901, Free Base, Biochemical (Cat# AAA6061791)
Full Name
PD-325901, Free Base (PD 0325901, MEK1/2 Inhibitor III)
Purity
Highly Purified
HPLC: ~95% TLC: ~95%
HPLC: ~95% TLC: ~95%
Pricing
$240/10 mg | $435/25 mg | $1,960/5x25 mg
Testing Data
(Data show effective inhibition of ERK1/2 phosphorylation in insulin + LIF treated 3T3-L1 adipocytes, using M2865-17B.)
MEK1 Inhibitor, Inhibitor (Cat# AAA655336)
Full Name
MEK1 Inhibitor (PD98059, 2'-amino-3'- methoxyflavone)
Gene Names
MAP2K1; CFC3; MEK1; MKK1; MAPKK1; PRKMK1
Purity
Highly Purified
~95% (HPLC)
~95% (HPLC)
Pricing
$560/5 mg | $2,515/5x5 mg
SDS-Page
(SDS-PAGE: 10ug of Raf-1, active.)
Raf1, Truncated, active, Active Protein (Cat# AAA637844)
Full Name
Raf1, Truncated, active, Recombinant, Human
Purity
Highly Purified
~70%
~70%
Pricing
$995/0.01 mg | $4,470/5x0.01 mg
Structure
(Structure of M2865-50A)
MEK1, 2 Inhibitor, Inhibitor (Cat# AAA655356)
Full Name
MEK1, 2 Inhibitor (U0126, Bis[amino[(2-aminophenyl)thio]methylene] Butanedinitrile)
Purity
Highly Purified
~99% (HPLC, TLC)
~99% (HPLC, TLC)
Pricing
$265/25 mg | $325/50 mg | $405/100 mg | $1,805/5x100 mg
Structure
(Structure of PD 98059)
MEK1 Inhibitor, Inhibitor (Cat# AAA655442)
Full Name
MEK1 Inhibitor (PD98059, 2'-amino-3'-methoxyflavone)
Gene Names
MAP2K1; CFC3; MEK1; MKK1; MAPKK1; PRKMK1
Purity
Highly Purified
~99%
~99%
Pricing
$275/5 mg | $1,225/5x5 mg
Structure
PD318088, Inhibitor (Cat# AAA578717)
Full Name
PD318088
Purity
99.7%
Pricing
$200/1 mg | $230/2 mg | $270/5 mg | $370/10 mg | $630/25 mg | $925/50 mg | $1,110/100 mg | $305/1 mL (in DMSO) | $4,720/5x100 mg
Structure
BIX 02188, Inhibitor (Cat# AAA578876)
Full Name
BIX 02188
Purity
99.0%
Pricing
$210/2 mg | $265/5 mg | $360/10 mg | $475/25 mg | $340/1 mL (in DMSO) | $1,880/5x25 mg
Structure
SL327, Inhibitor (Cat# AAA578127)
Full Name
SL327
Purity
98.0%
Pricing
$210/5 mg | $230/10 mg | $240/25 mg | $295/50 mg | $395/100 mg | $910/500 mg | $580/200 mg | $210/1 mL (in DMSO) | $3,820/5x500 mg
Structure
SCH772984, Inhibitor (Cat# AAA578640)
Full Name
SCH772984
Purity
99.75%
Pricing
$225/2 mg | $240/5 mg | $285/10 mg | $420/25 mg | $570/50 mg | $270/1 mL (in DMSO) | $2,295/5x50 mg
Structure
Pimasertib, Inhibitor (Cat# AAA578699)
Full Name
Pimasertib (AS-703026)
Purity
98.2%
Pricing
$175/2 mg | $195/5 mg | $205/10 mg | $235/25 mg | $285/50 mg | $355/100 mg | $415/200 mg | $200/1 mL (in DMSO) | $1,600/5x200 mg
Cobimetinib, Inhibitor (Cat# AAA578490)
Full Name
Cobimetinib
Purity
99.0%
Pricing
$195/1 mg | $205/2 mg | $225/5 mg | $245/10 mg | $315/25 mg | $400/50 mg | $620/100 mg | $245/1 mL (in DMSO) | $2,525/5x100 mg
Immunohistochemistry (IHC)
(At 1/100 staining Human kidney cancer and adjacent normal tissues by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4 degree C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody.)
C-RAF, Polyclonal Antibody (Cat# AAA9613037)
Full Name
Phospho-C-RAF (Thr269) Antibody
Gene Names
RAF1; NS5; CRAF; Raf-1; c-Raf
Reactivity
Human, Mouse, Rat
Applications
IHC, EIA
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Pricing
$305/0.1 mL | $365/0.2 mL | $1,495/5x0.2 mL
Western Blot (WB)
(Western blot analysis of C-RAF (Phospho-Tyr340) using Jurkat whole cell lysates.-/+ means absence or presence of N peptide（non-phospho peptide) and P peptide(phospho peptide).)
C-RAF, Polyclonal Antibody (Cat# AAA9614221)
Full Name
Phospho-C-RAF (Tyr340) Antibody
Gene Names
RAF1; NS5; CRAF; Raf-1; c-Raf
Reactivity
Human, Mouse, Rat
Predicted Reactivity: Pig (100%), Bovine (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (100%)
Predicted Reactivity: Pig (100%), Bovine (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (100%)
Applications
WB, IF, ICC, EIA
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Pricing
$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL
C-RAF, Polyclonal Antibody (Cat# AAA9613945)
Full Name
C-RAF Antibody
Gene Names
RAF1; NS5; CRAF; Raf-1; c-Raf
Reactivity
Human
Applications
EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
C-RAF, Polyclonal Antibody (Cat# AAA9612992)
Full Name
Phospho-C-RAF (Ser642) Antibody
Gene Names
RAF1; NS5; CRAF; Raf-1; c-Raf
Reactivity
Human, Mouse, Rat
Applications
EIA
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Pricing
$305/0.1 mL | $365/0.2 mL | $1,495/5x0.2 mL
Immunofluorescence (IF)/Immunocytochemistry (ICC)
(Staining Hela cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25 degree C. Samples were then incubated with primary Ab(AF6969) and mouse anti-beta tubulin Ab(T0023) for 1 hour at 37 degree C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) Ab(Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) Ab(Green) were used as the secondary antibody.The nuclear counter stain is DAPI(blue).)
C-RAF, Polyclonal Antibody (Cat# AAA9613990)
Full Name
C-RAF Antibody
Gene Names
RAF1; NS5; CRAF; Raf-1; c-Raf
Reactivity
Human
Applications
IF, ICC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Structure
AZD8330, Inhibitor (Cat# AAA3606309)
Full Name
AZD8330
Purity
>98% (HPLC)
Pricing
$210/2 mg | $235/5 mg | $295/10 mg | $395/25 mg | $1,495/5x25 mg
Structure
5Z-7-Oxozeaenol, Inhibitor (Cat# AAA5754443)
Full Name
5Z-7-Oxozeaenol
Purity
98.00%
Pricing
$265/1 mg | $600/5 mg | $2,415/5x5 mg
Structure
BIX02188, Inhibitor (Cat# AAA3600367)
Full Name
BIX02188
Purity
>98% (HPLC)
Pricing
$205/2 mg | $250/5 mg | $340/10 mg | $440/25 mg | $1,700/5x25 mg
Structure
SL-327, Inhibitor (Cat# AAA3608391)
Full Name
SL-327
Purity
>98% (HPLC)
Pricing
$190/5 mg | $205/10 mg | $240/25 mg | $295/50 mg | $380/100 mg | $495/200 mg | $1,940/5x200 mg
Structure
AS703026, Inhibitor (Cat# AAA3600953)
Full Name
AS703026
Purity
>98% (HPLC)
Pricing
$200/5 mg | $210/10 mg | $280/25 mg | $305/50 mg | $375/100 mg | $500/200 mg | $1,975/5x200 mg
Antisauvagine-30 TFA, Inhibitor (Cat# AAA5752700)
Full Name
Antisauvagine-30 TFA
Purity
98.00%
Pricing
$640/1 mg | $1,655/5 mg | $7,150/5x5 mg
Structure
TAK-285, Inhibitor (Cat# AAA3607627)
Full Name
TAK-285
Purity
>98% (HPLC)
Pricing
$565/25 mg | $2,250/5x25 mg
Structure
RO4987655, Inhibitor (Cat# AAA3606352)
Full Name
RO4987655
Purity
>98% (HPLC)
Pricing
$280/2 mg | $335/5 mg | $475/10 mg | $715/25 mg | $2,930/5x25 mg
Epiberberine, Inhibitor (Cat# AAA5750948)
Full Name
Epiberberine
Purity
98.00%
Pricing
$200/1 mg | $265/1 mL (in DMSO) | $930/5x1 mL (in DMSO)
Structure
TAK-733, Inhibitor (Cat# AAA3600176)
Full Name
TAK-733
Purity
>98% (HPLC)
Pricing
$210/2 mg | $245/5 mg | $315/10 mg | $455/25 mg | $670/50 mg | $2,715/5x50 mg
Structure
Refametinib, Inhibitor (Cat# AAA3606603)
Full Name
Refametinib
Purity
>98% (HPLC)
Pricing
$190/2 mg | $210/5 mg | $240/10 mg | $310/25 mg | $1,105/5x25 mg
Chemical Structure
RO4927350, Inhibitor (Cat# AAA386670)
Full Name
RO4927350
Purity
>98%
Pricing
$340/5 mg | $570/10 mg | $1,085/25 mg | $1,780/50 mg | $7,965/5x50 mg
Structure
Trametinib DMSO solvate, Inhibitor (Cat# AAA5752199)
Full Name
Trametinib DMSO solvate
Purity
98.00%
Pricing
$195/10 mg | $205/25 mg | $215/50 mg | $240/100 mg | $295/200 mg | $200/1 mL (in DMSO) | $1,050/5x200 mg
Structure
PD98059, Inhibitor (Cat# AAA3602564)
Full Name
PD98059
Purity
>98% (HPLC)
Pricing
$190/5 mg | $200/10 mg | $230/25 mg | $240/50 mg | $310/100 mg | $390/200 mg | $1,470/5x200 mg
Structure
PD318088, Inhibitor (Cat# AAA3604343)
Full Name
PD318088
Purity
>98% (HPLC)
Pricing
$225/2 mg | $260/5 mg | $355/10 mg | $580/25 mg | $845/50 mg | $3,510/5x50 mg
Structure
U0126, Inhibitor (Cat# AAA3600579)
Full Name
U0126
Purity
>98% (HPLC)
Pricing
$190/5 mg | $200/10 mg | $210/25 mg | $235/50 mg | $250/100 mg | $295/200 mg | $1,015/5x200 mg
Structure
Selumetinib, Inhibitor (Cat# AAA3605266)
Full Name
Selumetinib
Purity
>98% (HPLC)
Pricing
$190/25 mg | $205/50 mg | $215/100 mg | $250/200 mg | $845/5x200 mg
Structure
Cobimetinib, Inhibitor (Cat# AAA3606676)
Full Name
Cobimetinib
Purity
>98% (HPLC)
Pricing
$215/5 mg | $240/10 mg | $305/25 mg | $575/100 mg | $2,285/5x100 mg
Structure
Trametinib, Inhibitor (Cat# AAA3606330)
Full Name
Trametinib
Purity
>98% (HPLC)
Pricing
$190/10 mg | $205/50 mg | $235/100 mg | $265/200 mg | $910/5x200 mg
Structure
SCH-772984, Inhibitor (Cat# AAA3606735)
Full Name
SCH-772984
Purity
>98% (HPLC)
Pricing
$215/2 mg | $235/5 mg | $275/10 mg | $395/25 mg | $530/50 mg | $2,095/5x50 mg
Chemical Structure
Refametinib, Inhibitor (Cat# AAA387468)
Full Name
Refametinib (RDEA-119, BAY 86-9766)
Purity
>98%
Pricing
$295/10 mg | $385/25 mg | $740/50 mg | $1,230/100 mg | $5,490/5x100 mg
Structure
PD-184352, Inhibitor (Cat# AAA3603381)
Full Name
PD-184352
Purity
>98% (HPLC)
Pricing
$200/5 mg | $215/10 mg | $285/25 mg | $365/50 mg | $535/100 mg | $715/200 mg | $2,925/5x200 mg
Structure
GDC-0623, Inhibitor (Cat# AAA3607157)
Full Name
GDC-0623
Purity
>98% (HPLC)
Pricing
$210/2 mg | $330/10 mg | $420/25 mg | $540/50 mg | $710/100 mg | $2,920/5x100 mg
Structure
BI-847325, Inhibitor (Cat# AAA3600762)
Full Name
BI-847325
Purity
>98% (HPLC)
Pricing
$200/2 mg | $235/5 mg | $300/10 mg | $455/25 mg | $690/50 mg | $870/100 mg | $3,620/5x100 mg
Structure
RO-5126766, Inhibitor (Cat# AAA3606775)
Full Name
RO-5126766
Purity
>98% (HPLC)
Pricing
$660/50 mg | $2,680/5x50 mg
