Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Immunohistochemistry (IHC) (Anti-TNFRSF19 / TROY antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Rabbit anti-Human, Mouse TNFRSF19 / TROY Polyclonal Antibody | anti-TNFRSF19 antibody

Rabbit Polyclonal (IgG) to Human TNFRSF19 / TROY

Gene Names
TNFRSF19; TAJ; TROY; TRADE; TAJ-alpha
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot
Purity
Protein G Purified
Synonyms
TNFRSF19 / TROY; Polyclonal Antibody; Rabbit Polyclonal (IgG) to Human TNFRSF19 / TROY; Anti-TNFRSF19 / TROY Antibody (aa29-44) IHC-plus; TNFRSF19; TAJ-alpha; TRADE; TROY; Toxicity and JNK inducer; TAJ; Human TNFRSF19; anti-TNFRSF19 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
A mixture of synthetic peptides corresponding to amino acids 29-44, 204-219, and 409-421 of human TROY.
Purity/Purification
Protein G Purified
Form/Format
PBS, 0.05% BSA, 0.05% sodium azide.
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
423
Applicable Applications for anti-TNFRSF19 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes
IHC-P (5 ug/ml), WB (0.5 - 2 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
Target Species
Human
Immunogen Description
Synthetic peptide from human TNFRSF19 / TROY.
Immunogen Type
Synthetic peptide
Immunogen
TNFRSF19 / TROY antibody was raised against synthetic peptide from human TNFRSF19 / TROY.
Antigen Modification
aa29-44
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.

Immunohistochemistry (IHC)

(Anti-TNFRSF19 / TROY antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-TNFRSF19 / TROY antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Western Blot (WB)

(Western blot of TAJ/TROY using antibody in T98G, a human glioblastoma cell line lysate. A protein band of approximately 46 kD is detected.)

Western Blot (WB) (Western blot of TAJ/TROY using antibody in T98G, a human glioblastoma cell line lysate. A protein band of approximately 46 kD is detected.)
Related Product Information for anti-TNFRSF19 antibody
TNFRSF19, also known as TROY, TRADE or TAJ, is a member of the tumor necrosis factor receptor superfamily. It has the typical TNFR superfamily extracellular ligand-binding domain but lacks an intracellular death domain. TAJ has been shown to activate the c-Jun N-terminal kinase pathway and mediate Caspase-independent cell death Eby et al. (2000). TAJ has been shown by ISH to be expressed in the epithelium of many embryonic mouse tissues may play a role in embryonic development Kojima et al.
Product Categories/Family for anti-TNFRSF19 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
30,542 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 19 isoform 1
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 19
NCBI Official Symbol
TNFRSF19
NCBI Official Synonym Symbols
TAJ; TROY; TRADE; TAJ-alpha
NCBI Protein Information
tumor necrosis factor receptor superfamily member 19; toxicity and JNK inducer
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 19
UniProt Gene Name
TNFRSF19
UniProt Synonym Gene Names
TAJ; TROY
UniProt Entry Name
TNR19_HUMAN

NCBI Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Uniprot Description

TNFRSF19: Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 13q12.11-q12.3

Cellular Component: integral to membrane

Molecular Function: tumor necrosis factor receptor activity

Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; tumor necrosis factor-mediated signaling pathway; hair follicle development; apoptosis; JNK cascade

Research Articles on TNFRSF19

Similar Products

Product Notes

The TNFRSF19 tnfrsf19 (Catalog #AAA241871) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal (IgG) to Human TNFRSF19 / TROY reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TNFRSF19 / TROY can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB). IHC-P (5 ug/ml), WB (0.5 - 2 ug/ml) Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the TNFRSF19 tnfrsf19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TNFRSF19 / TROY, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.