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32 results for " Leptin Leptin Receptors" - showing 1-32
leptin, Active Protein (Cat# AAA400068)
Full Name
Pufferfish leptin (monomer and dimer)
Gene Names
lep; ob; xlep
Purity
The purity of recombinant fish leptin is greater than 98.0% as determined by:
(a) Gel filtration analysis.
(b) Analysis by reducing and non-reducing SDS-PAGE gel.
(c) RP-chromatography
(a) Gel filtration analysis.
(b) Analysis by reducing and non-reducing SDS-PAGE gel.
(c) RP-chromatography
Pricing
$210/0.1 mg | $540/0.5 mg | $840/1 mg | $2,700/5 mg | $4,755/10 mg | $11,060/100 mg
Immunohistochemistry (IHC)
(Formalin-fixed, paraffin-embedded human Kidney stained with Adiponectin Monoclonal Antibody (ADPN/1370).)
Adiponectin, Monoclonal Antibody (Cat# AAA4380327)
Full Name
Adiponectin (Marker of Obesity)
Gene Names
ADIPOQ; ACDC; ADPN; APM1; APM-1; GBP28; ACRP30; ADIPQTL1
Reactivity
Human. Others not known.
Applications
EIA, FC/FACS, IF, IHC
Pricing
$390/0.1 mg (With BSA & Azide at 0.2mg/mL) | $390/0.1 mg (Without BSA & Azide at 1mg/mL) | $215/0.02 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (Without BSA & Azide at 1mg/mL)
leptin binding domain, Active Protein (Cat# AAA400042)
Full Name
Chicken leptin binding domain
Purity
Greater than 99.0% as determined by:
(a) Gel filtration analysis.
(b) Analysis by reducing and non-reducing SDS-PAGE gel.
(a) Gel filtration analysis.
(b) Analysis by reducing and non-reducing SDS-PAGE gel.
Pricing
$360/0.05 mg | $560/0.1 mg | $1,960/0.5 mg | $3,355/1 mg | $10,145/5 mg
Activity Data
(Suppressor of cytokine signaling 3 (SOCS3) is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family that negatively regulates cytokine signal transduction. SOCS3 is feedback inhibitors of the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) signaling pathway. Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including gp130, LIF, erythropoietin, insulin, IL12, GCSF and leptin receptors. SOCS3 also can bind to JAK2 kinase inhibits its kinase activity and nhibits insulin signaling in adipose tissue and the liver. Besides, Glycoprotein 130 (gp130) has been identified as an interactor of SOCS3, thus a binding ELISA assay was conducted to detect the interaction of recombinant mouse SOCS3 and recombinant mouse gp130. Briefly, SOCS3 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to SOCS3-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-SOCS3 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of of SOCS3 and gp130 was shown in Figure 1, and this effect was in a dose dependent manner.)
Suppressors Of Cytokine Signaling 3 (SOCS3), Active Protein (Cat# AAA2097298)
Full Name
Active Suppressors Of Cytokine Signaling 3 (SOCS3)
Gene Names
Socs3; Cis3; Ef10; Ssi3; Cish3; EF-10; SSI-3
Reactivity
Mouse
Applications
Cell culture, Activity Assays
Purity
> 97%
Pricing
$215/0.01 mg | $450/0.05 mg | $690/0.1 mg | $850/0.2 mg | $1,660/0.5 mg | $2,470/1 mg | $6,035/5 mg
leptin binding domain, Active Protein (Cat# AAA400041)
Full Name
Human leptin binding domain
Purity
Purity:Greater than 99.0% as determined by:
(a) Gel filtration analysis.
(b) Analysis by reducing and non-reducing SDS-PAGE gel.
(a) Gel filtration analysis.
(b) Analysis by reducing and non-reducing SDS-PAGE gel.
Pricing
$360/0.05 mg | $560/0.1 mg | $1,960/0.5 mg | $3,355/1 mg | $10,145/5 mg
Activity Data
(Leptin is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Many of leptin's effects are mediated through neuropeptide- containing neurons and neuropeptide receptors in the hypothalamus. Although regulation of fat stores is deemed to be the primary function of leptin, it also plays a role in other physiological processes, as evidenced by its multiple sites of synthesis other than fat cells, and the multiple cell types beside hypothalamic cells that have leptin receptors. Besides, Hexokinase 3, White Cell (HK3) has been identified as an interactor of LEP, thus a binding ELISA assay was conducted to detect the interaction of recombinant human LEP and recombinant human HK3. Briefly, LEP were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to HK3-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-LEPpAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of of LEP and HK3 was shown in Figure 1, and this effect was in a dose dependent manner.)
Leptin (LEP), Active Protein (Cat# AAA2097261)
Full Name
Active Leptin (LEP)
Gene Names
LEP; OB; OBS; LEPD
Reactivity
Human
Applications
Cell culture, Activity Assays
Purity
> 90%
Pricing
$130/0.01 mg | $225/0.05 mg | $315/0.1 mg | $390/0.2 mg | $735/0.5 mg | $1,080/1 mg | $2,625/5 mg | $11,805/5x5 mg
Pufferfish Leptin, Active Protein (Cat# AAA143749)
Full Name
Recombinant Pufferfish Leptin
Purity
Greater than 99.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Pricing
$180/0.02 mg | $250/0.1 mg | $1,315/1 mg | $5,695/5x1 mg
SDS-Page
(Recombinant Human Leptin Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 13 kDa.)
Leptin, Active Protein (Cat# AAA9139631)
Full Name
Recombinant Human Leptin Protein
Gene Names
LEP; OB; OBS; LEPD
Purity
>92% by SDS-PAGE.
Pricing
$155/0.01 mg | $180/0.02 mg | $130/0.005 mg | $655/5x0.02 mg
Western Blot (WB)
(Western Blot: Lysates from unstimulated (lane 1) and Epo-stimulated (lane 2) HEK293 cells co-transfected with JAK2 and chimeric Epo-Leptin receptorsprobed with JAK2, phosphorylated (Janus Kinase 2) (Y1007, Y1008) Pab Rb xMo Catalog No: MBS620933 (2ug/ml). Arrow indicates phospho JAK 2 (~130kD).)
JAK2, Polyclonal Antibody (Cat# AAA620933)
Full Name
JAK2, phosphorylated (Janus Kinase 2) (Y1007, Y1008)
Gene Names
jak2b; jak2; JAK2bCA
Reactivity
Human, Mouse, Rat
Applications
EL/EIA, WB
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Pricing
$505/0.1 mg | $2,260/5x0.1 mg
Western Blot (WB)
(Western Blot Analysis: Representative lot data. Wild type HEK293 (lanes 1 and 2) cells or HEK293 cells transiently transfected with alpha JAK2 and ELR (chimera of the erythropoeitin and leptin receptors) (lanes 3 and 4) were immunoprecipitated with an anti-JAK2 antibody. Before lysis, cells were either left untreated (lane 1 and 3), or stimulated with Erythropoeitin (lane 2 and 4). Lysates were resolved by electrophoresis, transferred to PVDF membrane and probed with anti-phospho-JAK2 (Tyr317) (a 1ug/ml dilution of this lot). Proteins were visualized using a protein A conjugated to HRP and a chemiluminescence detection system. Arrow indicates phospho-JAK2 (Tyr317) (~130kD).)
JAK2, Polyclonal Antibody (Cat# AAA622484)
Full Name
JAK2, phosphorylated (Tyr317) (Janus Kinase 1, tyrosine-protein kinase JAK2)
Gene Names
jak2b; jak2; JAK2bCA
Reactivity
Human
Applications
WB
Purity
Serum
Serum
Serum
Pricing
$685/0.1 mL | $3,070/5x0.1 mL
Testing Data
(Image: LepRb staining in rat intestine.Detection was done using anti-chicken Cy2 conjugated antibodies (green color). Cell nuclei were counterstained with DAPI (blue color). Working dilution is 1:200-1:600.)
LepRb/OBRb, Antibody (Cat# AAA555405)
Full Name
LepRb/OBRb, Affinity Purified Antibody, Chicken
Reactivity
Rat
Applications
IF, IHC, WB
Pricing
$370/0.1 mL | $1,520/5x0.1 mL
Leptin receptor (LEPR), Recombinant Protein (Cat# AAA553292)
Full Name
Human Leptin receptor Recombinant (LEPR)
Purity
>98%, as determined by SDS-PAGE and HPLC
Pricing
$245/0.01 mg | $640/0.05 mg | $4,410/0.5 mg
Leptin Receptor, Polyclonal Antibody (Cat# AAA621035)
Full Name
Anti - Leptin Receptor (OBR, LEPR, B219, Obese Receptor)
Gene Names
LEPR; OBR; OB-R; CD295; LEP-R; DKFZp686B1731
Reactivity
Mouse
Applications
ELISA
Purity
Serum
Pricing
$755/0.1 mL | $3,395/5x0.1 mL
Leptin receptor Fc tag (LEPR), Recombinant Protein (Cat# AAA553334)
Full Name
Human Leptin receptor Fc tag Recombinant (LEPR)
Purity
>98%, as determined by SDS-PAGE and HPLC
Pricing
$245/0.02 mg | $640/0.1 mg | $4,410/1 mg
SOCS3, Positive Control (Cat# AAA543274)
Full Name
SOCS3 Antibody Western Blot Positive Control
Gene Names
SOCS3; CIS3; SSI3; ATOD4; Cish3; SSI-3; SOCS-3
Applications
WB
Pricing
$335/5 Applications | $1,350/5x5 Applications
SOCS3, Polyclonal Antibody (Cat# AAA544939)
Full Name
SOCS3 Antibody FITC-Conjugated
Gene Names
SOCS3; CIS3; SSI3; ATOD4; Cish3; SSI-3; SOCS-3
Reactivity
Human
Applications
EIA, WB
Pricing
$560/0.1 mg | $2,380/5x0.1 mg
Western Blot (WB)
SOCS3, Polyclonal Antibody (Cat# AAA544937)
Full Name
SOCS3 Antibody Affinity Purified
Gene Names
SOCS3; CIS3; SSI3; ATOD4; Cish3; SSI-3; SOCS-3
Reactivity
Human
Applications
EIA, WB
Pricing
$445/0.1 mg | $1,855/5x0.1 mg
Leptin R, Recombinant Protein (Cat# AAA692484)
Full Name
Human Leptin R
Gene Names
LEPR; OBR; OB-R; CD295; LEP-R; LEPRD
Reactivity
Human
Purity
> 98% by SDS-PAGE & HPLC analyses
Pricing
$250/0.02 mg | $395/0.1 mg | $1,565/5x0.1 mg
SOCS3, Polyclonal Antibody (Cat# AAA544938)
Full Name
SOCS3 Antibody BIOTIN-Conjugated
Gene Names
SOCS3; CIS3; SSI3; ATOD4; Cish3; SSI-3; SOCS-3
Reactivity
Human
Applications
EIA, WB
Pricing
$560/0.1 mg | $2,380/5x0.1 mg
SOCS3, Blocking Peptide (Cat# AAA544498)
Full Name
SOCS3 Antibody Antigenic Blocking Peptide
Gene Names
SOCS3; CIS3; SSI3; ATOD4; Cish3; SSI-3; SOCS-3
Applications
Immunocompetition, Immunodepletion
Pricing
$280/0.25 mg | $1,110/5x0.25 mg
Western Blot (WB)
(Western Blot: Lysates from unstimulated (lane 1) and Epo-stimulated (lane 2) HEK293 cells co-transfected with JAK2 and chimeric Epo-Leptin receptorsprobed with JAK2, phosphorylated (Janus Kinase 2) (Y1007, Y1008) Pab Rb xMo (2ug/ml). Arrow indicates phospho JAK 2 (~130kD).)
JAK2, Polyclonal Antibody (Cat# AAA6483720)
Full Name
JAK2, Phosphorylated (Janus Kinase 2) (Y1007, Y1008) (MaxLight 750)
Gene Names
JAK2; JTK10; THCYT3
Reactivity
Mouse, Human, Rat
Applications
WB
Purity
Purified by Protein A Affinity Chromatography.
Pricing
$910/0.1 mL | $4,090/5x0.1 mL
Western Blot (WB)
(Western Blot: Lysates from unstimulated (lane 1) and Epo-stimulated (lane 2) HEK293 cells co-transfected with JAK2 and chimeric Epo-Leptin receptorsprobed with JAK2, phosphorylated (Janus Kinase 2) (Y1007, Y1008) Pab Rb xMo (2ug/ml). Arrow indicates phospho JAK 2 (~130kD).)
JAK2, Polyclonal Antibody (Cat# AAA6483718)
Full Name
JAK2, Phosphorylated (Janus Kinase 2) (Y1007, Y1008) (MaxLight 550)
Gene Names
JAK2; JTK10; THCYT3
Reactivity
Mouse, Human, Rat
Applications
WB
Purity
Purified by Protein A Affinity Chromatography.
Pricing
$910/0.1 mL | $4,090/5x0.1 mL
Western Blot (WB)
(Western Blot: Lysates from unstimulated (lane 1) and Epo-stimulated (lane 2) HEK293 cells co-transfected with JAK2 and chimeric Epo-Leptin receptorsprobed with JAK2, phosphorylated (Janus Kinase 2) (Y1007, Y1008) Pab Rb xMo (2ug/ml). Arrow indicates phospho JAK 2 (~130kD).)
JAK2, Polyclonal Antibody (Cat# AAA6483721)
Full Name
JAK2, Phosphorylated (Janus Kinase 2) (Y1007, Y1008) (PE)
Gene Names
JAK2; JTK10; THCYT3
Reactivity
Mouse, Human, Rat
Applications
WB
Purity
Purified by Protein A Affinity Chromatography.
Pricing
$910/0.1 mL | $4,090/5x0.1 mL
Western Blot (WB)
(Western Blot: Lysates from unstimulated (lane 1) and Epo-stimulated (lane 2) HEK293 cells co-transfected with JAK2 and chimeric Epo-Leptin receptorsprobed with JAK2, phosphorylated (Janus Kinase 2) (Y1007, Y1008) Pab Rb xMo (2ug/ml). Arrow indicates phospho JAK 2 (~130kD).)
JAK2, Polyclonal Antibody (Cat# AAA6483719)
Full Name
JAK2, Phosphorylated (Janus Kinase 2) (Y1007, Y1008) (MaxLight 650)
Gene Names
JAK2; JTK10; THCYT3
Reactivity
Mouse, Human, Rat
Applications
WB
Purity
Purified by Protein A Affinity Chromatography.
Pricing
$910/0.1 mL | $4,090/5x0.1 mL
Western Blot (WB)
(Western Blot: Lysates from unstimulated (lane 1) and Epo-stimulated (lane 2) HEK293 cells co-transfected with JAK2 and chimeric Epo-Leptin receptorsprobed with JAK2, phosphorylated (Janus Kinase 2) (Y1007, Y1008) Pab Rb xMo (2ug/ml). Arrow indicates phospho JAK 2 (~130kD).)
JAK2, Polyclonal Antibody (Cat# AAA6483714)
Full Name
JAK2, Phosphorylated (Janus Kinase 2) (Y1007, Y1008) (FITC)
Gene Names
JAK2; JTK10; THCYT3
Reactivity
Mouse, Human, Rat
Applications
WB
Purity
Purified by Protein A Affinity Chromatography.
Pricing
$910/0.1 mL | $4,090/5x0.1 mL
Western Blot (WB)
(Western Blot: Lysates from unstimulated (lane 1) and Epo-stimulated (lane 2) HEK293 cells co-transfected with JAK2 and chimeric Epo-Leptin receptorsprobed with JAK2, phosphorylated (Janus Kinase 2) (Y1007, Y1008) Pab Rb xMo (2ug/ml). Arrow indicates phospho JAK 2 (~130kD).)
JAK2, Polyclonal Antibody (Cat# AAA6483712)
Full Name
JAK2, Phosphorylated (Janus Kinase 2) (Y1007, Y1008) (APC)
Gene Names
JAK2; JTK10; THCYT3
Reactivity
Mouse, Human, Rat
Applications
WB
Purity
Purified by Protein A Affinity Chromatography.
Pricing
$910/0.1 mL | $4,090/5x0.1 mL
Western Blot (WB)
(Western Blot: Lysates from unstimulated (lane 1) and Epo-stimulated (lane 2) HEK293 cells co-transfected with JAK2 and chimeric Epo-Leptin receptorsprobed with JAK2, phosphorylated (Janus Kinase 2) (Y1007, Y1008) Pab Rb xMo (2ug/ml). Arrow indicates phospho JAK 2 (~130kD).)
JAK2, Polyclonal Antibody (Cat# AAA6483716)
Full Name
JAK2, Phosphorylated (Janus Kinase 2) (Y1007, Y1008) (MaxLight 405)
Gene Names
JAK2; JTK10; THCYT3
Reactivity
Mouse, Human, Rat
Applications
WB
Purity
Purified by Protein A Affinity Chromatography.
Pricing
$910/0.1 mL | $4,090/5x0.1 mL
Western Blot (WB)
(Western Blot: Lysates from unstimulated (lane 1) and Epo-stimulated (lane 2) HEK293 cells co-transfected with JAK2 and chimeric Epo-Leptin receptorsprobed with JAK2, phosphorylated (Janus Kinase 2) (Y1007, Y1008) Pab Rb xMo (2ug/ml). Arrow indicates phospho JAK 2 (~130kD).)
JAK2, Polyclonal Antibody (Cat# AAA6483713)
Full Name
JAK2, Phosphorylated (Janus Kinase 2) (Y1007, Y1008) (Biotin)
Gene Names
JAK2; JTK10; THCYT3
Reactivity
Mouse, Human, Rat
Applications
WB
Purity
Purified by Protein A Affinity Chromatography.
Pricing
$910/0.1 mL | $4,090/5x0.1 mL
Western Blot (WB)
(Western Blot: Lysates from unstimulated (lane 1) and Epo-stimulated (lane 2) HEK293 cells co-transfected with JAK2 and chimeric Epo-Leptin receptorsprobed with JAK2, phosphorylated (Janus Kinase 2) (Y1007, Y1008) Pab Rb xMo (2ug/ml). Arrow indicates phospho JAK 2 (~130kD).)
JAK2, Polyclonal Antibody (Cat# AAA6483711)
Full Name
JAK2, Phosphorylated (Janus Kinase 2) (Y1007, Y1008) (AP)
Gene Names
JAK2; JTK10; THCYT3
Reactivity
Mouse, Human, Rat
Applications
WB
Purity
Purified by Protein A Affinity Chromatography.
Pricing
$910/0.1 mL | $4,090/5x0.1 mL
Western Blot (WB)
(Western Blot: Lysates from unstimulated (lane 1) and Epo-stimulated (lane 2) HEK293 cells co-transfected with JAK2 and chimeric Epo-Leptin receptorsprobed with JAK2, phosphorylated (Janus Kinase 2) (Y1007, Y1008) Pab Rb xMo (2ug/ml). Arrow indicates phospho JAK 2 (~130kD).)
JAK2, Polyclonal Antibody (Cat# AAA6483715)
Full Name
JAK2, Phosphorylated (Janus Kinase 2) (Y1007, Y1008) (HRP)
Gene Names
JAK2; JTK10; THCYT3
Reactivity
Mouse, Human, Rat
Applications
WB
Purity
Purified by Protein A Affinity Chromatography.
Pricing
$910/0.1 mL | $4,090/5x0.1 mL
Western Blot (WB)
(Western Blot: Lysates from unstimulated (lane 1) and Epo-stimulated (lane 2) HEK293 cells co-transfected with JAK2 and chimeric Epo-Leptin receptorsprobed with JAK2, phosphorylated (Janus Kinase 2) (Y1007, Y1008) Pab Rb xMo (2ug/ml). Arrow indicates phospho JAK 2 (~130kD).)
JAK2, Polyclonal Antibody (Cat# AAA6483717)
Full Name
JAK2, Phosphorylated (Janus Kinase 2) (Y1007, Y1008) (MaxLight 490)
Gene Names
JAK2; JTK10; THCYT3
Reactivity
Mouse, Human, Rat
Applications
WB
Purity
Purified by Protein A Affinity Chromatography.
Pricing
$910/0.1 mL | $4,090/5x0.1 mL
SH2B adapter protein 1 (SH2B1), Recombinant Protein (Cat# AAA9018615)
Full Name
Recombinant Human SH2B adapter protein 1 (SH2B1)(T484A,V541A), partial
Gene Names
SH2B1; PSM; SH2B
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
$1,915/1 mg (E-Coli) | $510/0.1 mg (E-Coli) | $310/0.02 mg (E-Coli) | $8,395/5x1 mg (E-Coli)
