Rat roundabout, axon guidance receptor, homolog 1 (Drosophila) ELISA Kit | ROBO1 elisa kit
Rat Roundabout homolog 1, ROBO1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
putative axon guidance receptor [RGD, Feb 2006]
Uniprot Description
ROBO1: Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development. Belongs to the immunoglobulin superfamily. ROBO family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Cell adhesion; Motility/polarity/chemotaxis
Cellular Component: cell surface; cell soma; axon; cytoplasm; plasma membrane; integral to membrane; axolemma
Molecular Function: identical protein binding; protein binding; axon guidance receptor activity; LRR domain binding
Biological Process: caspase activation; axon guidance; central nervous system development; olfactory bulb interneuron development; regulation of dendrite morphogenesis; chemorepulsion involved in postnatal olfactory bulb interneuron migration; axon midline choice point recognition; negative regulation of mammary gland epithelial cell proliferation; negative regulation of cell proliferation; negative regulation of negative chemotaxis; cell migration during sprouting angiogenesis; spinal cord development; positive regulation of axonogenesis; homophilic cell adhesion
Research Articles on ROBO1
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Product Notes
The Rat ROBO1 robo1 (Catalog #AAA9320056) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9320056 ELISA Kit recognizes Rat ROBO1. It is sometimes possible for the material contained within the vial of "roundabout, axon guidance receptor, homolog 1 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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