IP-10 Active Protein | Cxcl10 active protein
IP-10, Human, Recombinant
Gene Names
Cxcl10; C7; IP10; CRG-2; INP10; IP-10; Ifi10; mob-1; Scyb10; gIP-10
Purity
Molecular Biology Grade98% by SDS-PAGE and HPLC. Endotoxin: 0.1ng/ug
Synonyms
IP-10; Human; Recombinant; Cxcl10 active protein
Host
Reombinant Human (E Coli)
Purity/Purification
Molecular Biology Grade
98% by SDS-PAGE and HPLC. Endotoxin: 0.1ng/ug
98% by SDS-PAGE and HPLC. Endotoxin: 0.1ng/ug
Form/Format
Supplied as a lyophilized powder. Reconstitute with sterile, ddH2O to a concentration of 0.1-1mg/ml. This solution can be diluted into water or other buffered solutions.
Biological Activity
Determined by its ability to chemoattract human T lymphocytes using a concentration range of 10-50ng/ml
Preparation and Storage
Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile ddH2O and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for Cxcl10 active protein
IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally it is angiostatic and mitogenic for vascular smooth muscle cells. Recombinant human IP-10 is an 8.5kD protein consisting of 77 amino acids including four conserved cysteine residues present in CXC chemokine.
Product Categories/Family for Cxcl10 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
8.6kD
NCBI Official Full Name
IP-10
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 10
NCBI Official Symbol
Cxcl10
NCBI Official Synonym Symbols
C7; IP10; CRG-2; INP10; IP-10; Ifi10; mob-1; Scyb10; gIP-10
NCBI Protein Information
C-X-C motif chemokine 10; gamma-IP10; OTTMUSP00000036425; interferon activated gene 10; small-inducible cytokine B10; interferon-gamma induced protein CRG-2; interferon-gamma-induced protein CRG-2; 10 kDa interferon gamma-induced protein; small inducible cytokine B subfamily (Cys-X-Cys), member 10
UniProt Protein Name
C-X-C motif chemokine 10
Protein Family
UniProt Gene Name
Cxcl10
UniProt Synonym Gene Names
Crg2; Ifi10; Inp10; Scyb10
UniProt Entry Name
CXL10_MOUSE
Uniprot Description
Function: In addition to its role as a proinflammatory cytokine, may participate in T-cell effector function and perhaps T-cell development.
Subcellular location: Secreted.
Tissue specificity: Expressed in the spleen, thymus, lymph nodes and liver. Ref.5
Induction: By interferon gamma.
Sequence similarities: Belongs to the intercrine alpha (chemokine CxC) family.
Research Articles on Cxcl10
Similar Products
Product Notes
The Cxcl10 cxcl10 (Catalog #AAA651038) is an Active Protein produced from Reombinant Human (E Coli) and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "IP-10, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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