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Testing Data

IP-10 active protein

Murine IP-10 (CXCL10)

Gene Names
Cxcl10; C7; IP10; CRG-2; INP10; IP-10; Ifi10; mob-1; Scyb10; gIP-10
Reactivity
Species Reactivity: Mouse
Cross Reactivity: Bacteria, Human
Purity
Above 98% as determined by SDS-PAGE Analysis.
Synonyms
IP-10; Murine IP-10 (CXCL10); Recombinant Murine IP-10 (CXCL10); IP-10 active protein
Ordering
For Research Use Only!
Host
E Coli
Reactivity
Species Reactivity: Mouse
Cross Reactivity: Bacteria, Human
Purity/Purification
Above 98% as determined by SDS-PAGE Analysis.
Sequence
IPLARTVRC NCIHIDDGP VRMRAIGKL EIIPASLSC PRVEIIATM KKNDEQRCL NPESKTIKN LMKAFSQKR SKRAP
Biological Activity
Assay #1:Determined by its ability to chemoattract IL-2 activated T cells using a concentration range of 0.1-10.0 ng/ml. Assay #2: Determined by its ability to chemoattract CXCR3 transfected/HEK293 cells using a con
Cell Type
Monocytes and Macrophages
Preparation and Storage
At -20 degree C

Testing Data

Testing Data
Related Product Information for IP-10 active protein
Murine IP-10 is produced by several cell types during the delayed type hypersensitivity response. IP-10 acts as a chemoattractant towards monocytes, lymphocytes, and certain T cells. Recombinant Murine IP-10 is a 8.7 kDa protein, containing 77 amino acid residues.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
10,789 Da
NCBI Official Full Name
C-X-C motif chemokine 10
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 10
NCBI Official Symbol
Cxcl10
NCBI Official Synonym Symbols
C7; IP10; CRG-2; INP10; IP-10; Ifi10; mob-1; Scyb10; gIP-10
NCBI Protein Information
C-X-C motif chemokine 10; gamma-IP10; interferon activated gene 10; small-inducible cytokine B10; interferon-gamma induced protein CRG-2; interferon-gamma-induced protein CRG-2; 10 kDa interferon gamma-induced protein; small inducible cytokine B subfamily (Cys-X-Cys), member 10
UniProt Protein Name
C-X-C motif chemokine 10
UniProt Gene Name
Cxcl10
UniProt Synonym Gene Names
Crg2; Ifi10; Inp10; Scyb10; Gamma-IP10; IP-10
UniProt Entry Name
CXL10_MOUSE

Uniprot Description

CXCL10: Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide; Chemokine

Cellular Component: extracellular space; cell; extracellular region; external side of plasma membrane

Molecular Function: heparin binding; CXCR3 chemokine receptor binding; chemokine activity; cytokine activity

Biological Process: response to lipopolysaccharide; positive regulation of leukocyte chemotaxis; positive regulation of cAMP metabolic process; chemotaxis; regulation of cell proliferation; G-protein coupled receptor protein signaling pathway; negative regulation of angiogenesis; positive regulation of cell proliferation; immune response; positive regulation of release of sequestered calcium ion into cytosol; inflammatory response; negative regulation of myoblast differentiation; defense response to virus; positive regulation of cell migration

Research Articles on IP-10

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Product Notes

The IP-10 cxcl10 (Catalog #AAA696103) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Murine IP-10 (CXCL10) reacts with Species Reactivity: Mouse Cross Reactivity: Bacteria, Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: IPLARTVRC NCIHIDDGP VRMRAIGKL EIIPASLSC PRVEIIATM KKNDEQRCL NPESKTIKN LMKAFSQKR SKRAP. It is sometimes possible for the material contained within the vial of "IP-10, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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