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SDS-PAGE

EphA3 recombinant protein

Recombinant Mouse EphA3 Protein (His tag)

Gene Names
Relt; Tnfrsf19l; E430021K24Rik
Purity
> 95 % as determined by SDS-PAGE
Synonyms
EphA3; Recombinant Mouse EphA3 Protein (His tag); EPHA3; EphA3 recombinant protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
> 95 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
436
Application Notes
The recombinant mouse EPHA3 comprises 532 amino acids and has a predicted molecular mass of 60.2 kDa. The apparent molecular mass of the protein is approximately 67.8 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Predicted N Terminal
Glu 21
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C

SDS-PAGE

SDS-PAGE
Related Product Information for EphA3 recombinant protein
Background: EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.

Description: A DNA sequence encoding the mouse EPHA3 (NP_796047.2) (Met1-His541) was expressed with a C-terminal polyhistidine tag.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,518 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 19L
NCBI Official Synonym Full Names
RELT tumor necrosis factor receptor
NCBI Official Symbol
Relt
NCBI Official Synonym Symbols
Tnfrsf19l; E430021K24Rik
NCBI Protein Information
tumor necrosis factor receptor superfamily member 19L
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 19L
Protein Family
UniProt Gene Name
Relt
UniProt Synonym Gene Names
Tnfrsf19l

Uniprot Description

RELT: Mediates activation of NF-kappa-B. May play a role in T- cell activation. Belongs to the RELT family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 7|7 E2

Cellular Component: integral to plasma membrane

Molecular Function: tumor necrosis factor receptor activity

Biological Process: immune response; inflammatory response; multicellular organismal development; positive regulation of MAPKKK cascade; programmed cell death; regulation of apoptosis; regulation of cell proliferation; response to lipopolysaccharide

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Product Notes

The EphA3 relt (Catalog #AAA2546618) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant mouse EPHA3 comprises 532 amino acids and has a predicted molecular mass of 60.2 kDa. The apparent molecular mass of the protein is approximately 67.8 kDa in SDS-PAGE under reducing conditions due to glycosylation. Researchers should empirically determine the suitability of the EphA3 relt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EphA3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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