Human RAS guanyl releasing protein 3 (calcium and DAG-regulated) ELISA Kit | RASGRP3 elisa kit
Human Ras guanyl-releasing protein 3, RASGRP3 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008]
Uniprot Description
RASGRP3: Guanine nucleotide exchange factor (GEF) for Ras and Rap1. Belongs to the RASGRP family.
Protein type: GEFs; GEFs, Ras
Chromosomal Location of Human Ortholog: 2p25.1-p24.1
Cellular Component: integral to plasma membrane; perinuclear region of cytoplasm; plasma membrane
Molecular Function: diacylglycerol binding; signal transducer activity; Ras GTPase binding; guanyl-nucleotide exchange factor activity; calcium ion binding; kinase binding; Ras guanyl-nucleotide exchange factor activity
Biological Process: small GTPase mediated signal transduction; Ras protein signal transduction; MAPKKK cascade; positive regulation of GTPase activity
Research Articles on RASGRP3
Similar Products
Product Notes
The Human RASGRP3 rasgrp3 (Catalog #AAA9338889) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9338889 ELISA Kit recognizes Human RASGRP3. It is sometimes possible for the material contained within the vial of "RAS guanyl releasing protein 3 (calcium and DAG-regulated), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
