Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 860982(RERE Antibody) at dilution 1/20.(Original magnification: ×200))
Rabbit RERE Polyclonal Antibody | anti-RERE antibody
RERE Rabbit pAb
IHC: 1:25-1:100
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 860982(RERE Antibody) at dilution 1/20.(Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 860982(RERE Antibody) at dilution 1/20.(Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 860982(RERE Antibody) at dilution 1/20. (Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 860982(RERE Antibody) at dilution 1/20. (Original magnification: ×200))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. The encoded protein co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in mouse associates with histone deacetylase and is thought to function as a transcriptional co-repressor during embryonic development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Uniprot Description
RERE: Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death. A chromosomal aberration involving RERE is found in the neuroblastoma cell line. Translocation t(1;15)(p36.2;q24). 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nuclear receptor co-regulator; Transcription factor
Chromosomal Location of Human Ortholog: 1p36.23
Cellular Component: histone deacetylase complex; nucleus
Molecular Function: protein binding; zinc ion binding; sequence-specific DNA binding; poly-glutamine tract binding; chromatin binding; transcription factor activity
Biological Process: chromatin remodeling; regulation of transcription, DNA-dependent; transcription, DNA-dependent; multicellular organismal development; NLS-bearing substrate import into nucleus
Research Articles on RERE
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Product Notes
The RERE rere (Catalog #AAA4758337) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RERE Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RERE can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P). ELISA: 1:2000-1:5000 IHC: 1:25-1:100. Researchers should empirically determine the suitability of the RERE rere for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RERE, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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