RAB11B recombinant protein

RAB11B Protein, Human, Recombinant (His Tag)

Cat. Num. AAA8121920

• Gene Names: RAB11B; H-YPT3
• Purity: >95% as determined by SDS-PAGE
• Synonyms: RAB11B; RAB11B Protein; Human; Recombinant (His Tag); Human RAB11B Protein (His Tag); H-YPT3 Protein; member RAS oncogene family; RAB11B recombinant protein

• Host: HEK293 Cells
• Purity/Purification: >95% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Gly2-Cys215

• Species: Human
• Endotoxin: <1.0EU per ug protein as determined by the LAL method.
• Predicted N Terminal: His
• Tag: N-His
• Protein Construction: A DNA sequence encoding the human RAB11B (ABQ59034.1)(Gly2-Cys215) was expressed with a polyhistidine tag at the N-terminus.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

SDS-Page

Related Product Information for RAB11B recombinant protein

Background: The two recurrent dominant mutations in RAB11B leading to a neurodevelopmental syndrome, likely caused by altered GDP/GTP binding that inactivate the protein and induce GEF binding and protein mislocalization.

Product Categories/Family for RAB11B recombinant protein

Autophagy Pathway

NCBI and Uniprot Product Information

• NCBI GI #: 148342496
• NCBI GeneID: 9230
• Molecular Weight: 19,971 Da
• NCBI Official Full Name: RAB11B protein
• NCBI Official Synonym Full Names: RAB11B, member RAS oncogene family
• NCBI Official Symbol: RAB11B
• NCBI Official Synonym Symbols: H-YPT3
• NCBI Protein Information: ras-related protein Rab-11B
• Protein Family: Ras-related protein

NCBI Description

The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010]