Rabbit RAB11B Polyclonal Antibody | anti-RAB11B antibody

RAB11B-Specific Rabbit Polyclonal

Cat. Num. AAA7603222

• Gene Names: RAB11B; H-YPT3
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: RAB11B; Polyclonal Antibody; RAB11B-Specific Rabbit Polyclonal; anti-RAB11B antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 218

• Applicable Applications for anti-RAB11B antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen: RAB11B, member RAS oncogene family
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human lung using MBS7603222 (RAB11B-Specific antibody) at dilution of 1:100)

Western Blot (WB)

(human brain tissue were subjected to SDS PAGE followed by western blot with MBS7603222 (RAB11B-Specific antibody) at dilution of 1:300)

NCBI and Uniprot Product Information

• NCBI GI #: 49456343
• NCBI GeneID: 9230
• UniProt Accession #: Q6FHR0; Q2YDT2; Q5U0I1; Q6FI42; Q8NI07; A5YM50; B2R7I4; B4DMK0; D6W671; Q15907
• Molecular Weight: 19,971 Da
• NCBI Official Full Name: RAB11B, partial
• NCBI Official Synonym Full Names: RAB11B, member RAS oncogene family
• NCBI Official Symbol: RAB11B
• NCBI Official Synonym Symbols: H-YPT3
• NCBI Protein Information: ras-related protein Rab-11B
• UniProt Protein Name: Ras-related protein Rab-11B
• Protein Family: Ras-related protein
• UniProt Gene Name: RAB11B
• UniProt Synonym Gene Names: YPT3
• UniProt Entry Name: RB11B_HUMAN

NCBI Description

The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010]

Uniprot Description

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab plays a role in endocytic recycling, regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR, epithelial sodium channel/ENaC, potassium voltage-gated channel, and voltage-dependent L-type calcium channel. May also regulate constitutive and regulated secretion, like insulin granule exocytosis. Required for melanosome transport and release from melanocytes. Also regulates V-ATPase intracellular transport in response to extracellular acidosis.