Rabbit anti-Human CD163L1 Polyclonal Antibody | anti-CD163L1 antibody

CD163L1, CT (CD163L1, CD163B, M160, Scavenger receptor cysteine-rich type 1 protein M160, CD163 antigen-like 1, CD163b) (FITC)

Cat. Num. AAA6282820

• Gene Names: CD163L1; M160; CD163B
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A and Peptide Affinity Chromatography.
• Synonyms: CD163L1; Polyclonal Antibody; CT (CD163L1; CD163B; M160; Scavenger receptor cysteine-rich type 1 protein M160; CD163 antigen-like 1; CD163b) (FITC); CD163b; anti-CD163L1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human CD163L1.
• Purity/Purification: Purified by Protein A and Peptide Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-CD163L1 antibody: Western Blot (WB), FLISA
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1401-1430 in the C-terminal region of human CD163L1, UniProt Accession #Q9NR16.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis in NCI-H292 cell line lysates (35ug/lane) usingMBS6005334. This demonstrates that MBS6005334 detected the CD163L1 protein (arrow).)

Related Product Information for anti-CD163L1 antibody

This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. The SRCR family is defined by a 100-110 amino acid SRCR domain, which may mediate protein-protein interaction and ligand binding. The encoded protein contains twelve SRCR domains, a transmembrane region and a cytoplasmic domain. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has not been determined.

Product Categories/Family for anti-CD163L1 antibody

Antibodies; Receptors; Scavenger

References

1. Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010). 2. Davila, S., et al. Genes Immun. 11(3):232-238(2010). 3. Van Gorp, H., et al. J. Virol. 84(6):3101-3105(2010). 4. Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004). 5. Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003).

NCBI and Uniprot Product Information

• NCBI GI #: 50659091
• NCBI GeneID: 283316
• NCBI Accession #: NP_777601.2
• NCBI GenBank Nucleotide #: NM_174941.5
• UniProt Accession #: Q9NR16; Q2M3B7; Q6UWC2; B4E0G7; C9JHR7; E7EVK4
• Molecular Weight: 159,239 Da
• NCBI Official Full Name: scavenger receptor cysteine-rich type 1 protein M160 isoform 2
• NCBI Official Synonym Full Names: CD163 molecule-like 1
• NCBI Official Symbol: CD163L1
• NCBI Official Synonym Symbols: M160; CD163B
• NCBI Protein Information: scavenger receptor cysteine-rich type 1 protein M160; CD163 antigen B; CD163 antigen-like 1
• UniProt Protein Name: Scavenger receptor cysteine-rich type 1 protein M160
• Protein Family: Scavenger receptor cysteine-rich type 1 protein
• UniProt Gene Name: CD163L1
• UniProt Synonym Gene Names: CD163B; M160; UNQ6434/PRO23202
• UniProt Entry Name: C163B_HUMAN

NCBI Description

This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. The SRCR family is defined by a 100-110 amino acid SRCR domain, which may mediate protein-protein interaction and ligand binding. The encoded protein contains twelve SRCR domains, a transmembrane region and a cytoplasmic domain. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

Uniprot Description

CD163L1: a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. The SRCR family is defined by a 100-110 amino acid SRCR domain, which may mediate protein-protein interaction and ligand binding. The encoded protein contains twelve SRCR domains, a transmembrane region and a cytoplasmic domain. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13.3

Cellular Component: integral to membrane; extracellular region; plasma membrane

Molecular Function: scavenger receptor activity

Biological Process: receptor-mediated endocytosis