Human POU domain, class 3, transcription factor 4 ELISA Kit | POU3F4 elisa kit
Human POU domain, class 3, transcription factor 4 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the POU-III class of neural transcription factors. This family member plays a role in inner ear development. The protein is thought to be involved in the mediation of epigenetic signals which induce striatal neuron-precursor differentiation. Mutations in this gene are associated with X chromosome-linked nonsyndromic mixed deafness. [provided by RefSeq, Dec 2012]
Uniprot Description
Oct9: Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain. Defects in POU3F4 are a cause of deafness X-linked type 2 (DFNX2). A mixed type of deafness characterized by both conductive hearing loss resulting from stapes (perilymphatic gusher) fixation and progressive sensorineural deafness. Belongs to the POU transcription factor family. Class- 3 subfamily.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: Xq21.1
Cellular Component: nucleus
Molecular Function: AT DNA binding; transcription factor activity
Biological Process: forebrain neuron differentiation; regulation of transcription from RNA polymerase II promoter; sensory perception of sound; transcription from RNA polymerase II promoter
Disease: Deafness, X-linked 2
Research Articles on POU3F4
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Product Notes
The Human POU3F4 pou3f4 (Catalog #AAA2882903) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2882903 ELISA Kit recognizes Human POU3F4. It is sometimes possible for the material contained within the vial of "POU domain, class 3, transcription factor 4, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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