Western Blot (WB)
(WFIKKN2 Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the WFIKKN2 Antibody detected the WFIKKN2 protein (arrow).)
Rabbit anti-Human, mouse WFIKKN2 Polyclonal Antibody | anti-WFIKKN2 antibody
WFIKKN2 Antibody (C-term)
Western Blot (WB)
(WFIKKN2 Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the WFIKKN2 Antibody detected the WFIKKN2 protein (arrow).)
Western Blot (WB)
(WFIKKN2 Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the WFIKKN2 Antibody detected the WFIKKN2 protein (arrow).)
domain, immunoglobulin domain, two tandem Kunitz domains, and an
NTR domain. This gene encodes a WFIKKN1-related protein which has
the same domain organization as the WFIKKN1 protein. The WAP-type,
follistatin type, Kunitz-type, and NTR-type protease inhibitory
domains may control the action of multiple types of proteases.
Kondas, K., et al. J. Biol. Chem. 283(35):23677-23684(2008)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Hill, J.J., et al. Mol. Endocrinol. 17(6):1144-1154(2003)
Nagy, A., et al. Eur. J. Biochem. 270(9):2101-2107(2003)
NCBI and Uniprot Product Information
NCBI Description
The WFIKKN1 protein contains a WAP domain, follistatin domain, immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. This gene encodes a WFIKKN1-related protein which has the same domain organization as the WFIKKN1 protein. The WAP-type, follistatin type, Kunitz-type, and NTR-type protease inhibitory domains may control the action of multiple types of proteases. [provided by RefSeq, Jul 2008]
Uniprot Description
WFIKKN2: Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity. Inhibits the biological activity of mature myostatin, but not activin. Belongs to the WFIKKN family.
Protein type: Secreted, signal peptide; Secreted; Inhibitor
Chromosomal Location of Human Ortholog: 17q21.33
Cellular Component: extracellular region
Molecular Function: serine-type endopeptidase inhibitor activity; metalloendopeptidase inhibitor activity
Biological Process: transforming growth factor beta receptor signaling pathway; palate development; negative regulation of protein binding; muscle fiber development; skeletal development; negative regulation of DNA binding
Research Articles on WFIKKN2
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Product Notes
The WFIKKN2 wfikkn2 (Catalog #AAA9205555) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 535-564. The WFIKKN2 Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's WFIKKN2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the WFIKKN2 wfikkn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "WFIKKN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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