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Western Blot (WB) (WFIKKN2 Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the WFIKKN2 Antibody detected the WFIKKN2 protein (arrow).)

Rabbit anti-Human, Mouse WFIKKN2 Polyclonal Antibody | anti-WFIKKN2 antibody

WFIKKN2, CT (WFIKKN2, GASP1, WFIKKNRP, WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 2, Growth and differentiation factor-associated serum protein 1, WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing-related protein

Gene Names
WFIKKN2; GASP-1; WFDC20B; hGASP-1; WFIKKNRP
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
WFIKKN2; Polyclonal Antibody; CT (WFIKKN2; GASP1; WFIKKNRP; WAP; kazal; immunoglobulin; kunitz and NTR domain-containing protein 2; Growth and differentiation factor-associated serum protein 1; follistatin; kunitz and NTR domain-containing-related protein; WFIKKN-related protein; anti-WFIKKN2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
Applicable Applications for anti-WFIKKN2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
WFIKKN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 534-564 amino acids from the C-terminal region of human WFIKKN2.
Conjugate
HRP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(WFIKKN2 Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the WFIKKN2 Antibody detected the WFIKKN2 protein (arrow).)

Western Blot (WB) (WFIKKN2 Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the WFIKKN2 Antibody detected the WFIKKN2 protein (arrow).)
Related Product Information for anti-WFIKKN2 antibody
The WFIKKN1 protein contains a WAP domain, follistatin domain, immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. This gene encodes a WFIKKN1-related protein which has the same domain organization as the WFIKKN1 protein. The WAP-type, follistatin type, Kunitz-type, and NTR-type protease inhibitory domains may control the action of multiple types of proteases.
Product Categories/Family for anti-WFIKKN2 antibody
References
Saremi, A., et al. Mol. Cell. Endocrinol. 317 (1-2), 25-30 (2010): Kondas, K., et al. J. Biol. Chem. 283(35):23677-23684(2008). Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003). Hill, J.J., et al. Mol. Endocrinol. 17(6):1144-1154(2003). Nagy, A., et al. Eur. J. Biochem. 270(9):2101-2107(2003).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
63,941 Da
NCBI Official Full Name
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2
NCBI Official Synonym Full Names
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
NCBI Official Symbol
WFIKKN2
NCBI Official Synonym Symbols
GASP-1; WFDC20B; hGASP-1; WFIKKNRP
NCBI Protein Information
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2; WFIKKN-related protein; WAP four-disulfide core domain 20B; multivalent protease inhibitor protein; WAP, FS, Ig, two KU and NTR module related protein; growth and differentiation fact
UniProt Protein Name
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2
UniProt Gene Name
WFIKKN2
UniProt Synonym Gene Names
GASP1; WFIKKNRP; GASP-1; hGASP-1
UniProt Entry Name
WFKN2_HUMAN

NCBI Description

The WFIKKN1 protein contains a WAP domain, follistatin domain, immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. This gene encodes a WFIKKN1-related protein which has the same domain organization as the WFIKKN1 protein. The WAP-type, follistatin type, Kunitz-type, and NTR-type protease inhibitory domains may control the action of multiple types of proteases. [provided by RefSeq, Jul 2008]

Uniprot Description

WFIKKN2: Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity. Inhibits the biological activity of mature myostatin, but not activin. Belongs to the WFIKKN family.

Protein type: Secreted, signal peptide; Inhibitor; Secreted

Chromosomal Location of Human Ortholog: 17q21.33

Cellular Component: extracellular region

Molecular Function: serine-type endopeptidase inhibitor activity; metalloendopeptidase inhibitor activity

Biological Process: transforming growth factor beta receptor signaling pathway; palate development; muscle fiber development; negative regulation of protein binding; skeletal development; negative regulation of DNA binding

Research Articles on WFIKKN2

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Product Notes

The WFIKKN2 wfikkn2 (Catalog #AAA6363559) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The WFIKKN2, CT (WFIKKN2, GASP1, WFIKKNRP, WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 2, Growth and differentiation factor-associated serum protein 1, WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing-related protein reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's WFIKKN2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the WFIKKN2 wfikkn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "WFIKKN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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