Immunohistochemistry (IHC)
(Immunochemical staining of human USP32 in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human USP32 Polyclonal Antibody | anti-USP32 antibody
Anti-USP32 Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
USP32; Polyclonal Antibody; Anti-USP32 Antibody; Rabbit Polyclonal; USP32 Antibody; Rabbit PAb; Antigen Affinity Purified; ubiquitin specific peptidase 32; Anti-NY-REN-60 Antibody; Anti-USP10 Antibody; anti-USP32 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human USP32
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-USP32 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:50-1:200
Immunogen
E Coli-derived Human USP32 fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human USP32 fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human USP32 in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human USP32 in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human USP32 in human testis with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human USP32 in human testis with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-USP32 antibody
Ubiquitin specific protease 32 (USP32), on chromosomal band 17q23.1-17q23.2, is a highly conserved but uncharacterized gene that gave rise during evolution to a well-known hominoid-specific proto-oncogene, USP6. USP is a family of deubiquitinating enzymes essential to the functioning of the ubiquitin-proteasome system. In mammals, USP32 is known to be associated with cancer and immunity. USP32, a member of the ubiquitin-specific proteases family, has been implicated in the development of breast cancer and small lung cancer. USP32 is important for small cell lung cancer (SCLC) progression and might be a potential target for molecular therapy of SCLC. Loss of USP32 inhibits late endosome (LE) transport and recycling of LE cargos, resulting in dispersion and swelling of the late compartment.
References
Sun YL, et al. (2020) Pol-mir-363-3p plays a significant role in the immune defense of japanese flounder paralichthys olivaceus against bacterial and viral infection. Fish Shellfish Immunol 104 439-446.Hu W, et al. (2017) Downregulation of usp32 inhibits cell proliferation, migration and invasion in human small cell lung cancer. Cell Prolif 50 (4): e12343.Akhavantabasi S, et al. (2010) Usp32 is an active, membrane-bound ubiquitin protease overexpressed in breast cancers. Mamm Genome 21 (7-8): 388-397.
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Product Notes
The USP32 (Catalog #AAA8109309) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-USP32 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's USP32 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:50-1:200. Researchers should empirically determine the suitability of the USP32 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "USP32, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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