Immunohistochemistry (IHC)
(Immunochemical staining of human EPB41L3 in human testis with rabbit polyclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human EPB41L3 Polyclonal Antibody | anti-EPB41L3 antibody
Anti-EPB41L3 Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
EPB41L3; Polyclonal Antibody; Anti-EPB41L3 Antibody; Rabbit Polyclonal; EPB41L3 Antibody; Rabbit PAb; Antigen Affinity Purified; anti-EPB41L3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human EPB41L3
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-EPB41L3 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:500-1:3000
Immunogen
E Coli-derived Human EPB41L3 fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human EPB41L3 fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human EPB41L3 in human testis with rabbit polyclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human EPB41L3 in human testis with rabbit polyclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human EPB41L3 in human small intestine with rabbit polyclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human EPB41L3 in human small intestine with rabbit polyclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-EPB41L3 antibody
Erythrocyte membrane protein band 4.1 like 3 (EPB41L3, also known as DAL-1 and 4.1B)) may play a role as a metastasis suppressor by supporting regular arrangements of actin stress fibres and alleviating the increase in cell motility associated with enhanced metastatic potential. EPB41L3 is a candidate tumor suppressor gene (TSG) in various cancers, including ovarian cancer, esophageal squamous cell carcinoma (ESCC) and non-small-cell lung carcinoma. EPB41L3 may serve a potential therapeutic target and a prognostic indicator in these cancers.
References
Zeng R, et al. (2016) Epb41l3 suppresses esophageal squamous cell carcinoma invasion and inhibits mmp2 and mmp9 expression. Cell Biochem Funct 34 (3): 133-141.Huisman C, et al. (2015) Prolonged re-expression of the hypermethylated gene epb41l3 using artificial transcription factors and epigenetic drugs. Epigenetics 10 (5): 384-396.Dafou D, et al. (2010) Microcell-mediated chromosome transfer identifies epb41l3 as a functional suppressor of epithelial ovarian cancers. Neoplasia 12 (7): 579-589.
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Product Notes
The EPB41L3 (Catalog #AAA8110414) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-EPB41L3 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's EPB41L3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:500-1:3000. Researchers should empirically determine the suitability of the EPB41L3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EPB41L3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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